Hotels in Santa Ana
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in Santa Ana?

Hostal Casa Buho
Hostal Casa BuhoSanta Ana
8.6 out of 10, Excellent, (22 reviews)
The price is $48
$58 total
includes taxes & fees
Mar 7 - Mar 8

Casa Buho B&B
Casa Buho B&BSanta Ana
9.2 out of 10, Wonderful, (50 reviews)
The price is $66
$80 total
includes taxes & fees
Feb 22 - Feb 23

La Capitania de San Pedro
La Capitania de San Pedro2.9 km from Santa Ana
9.6 out of 10, Exceptional, (14 reviews)
The price is $74
$90 total
includes taxes & fees
Feb 22 - Feb 23

El Carmen Hotel
El Carmen HotelHistoric Center, 1.3 km from Santa Ana
9.0 out of 10, Wonderful, (738 reviews)
The price is $111
$136 total
includes taxes & fees
Mar 17 - Mar 18

Santo Cielo by Casa Santo Domingo
Santo Cielo by Casa Santo Domingo0.9 km from Santa Ana
9.4 out of 10, Exceptional, (529 reviews)
The price is $212
$271 total
includes taxes & fees
Feb 22 - Feb 23

Mestizo Cortijo
Mestizo Cortijo4.3 km from Santa Ana
9.0 out of 10, Wonderful, (108 reviews)
The price is $132
$161 total
includes taxes & fees
Mar 22 - Mar 23

Yes Please Hostel
Yes Please Hostel0.7 km from Santa Ana
8.0 out of 10, Very Good, (22 reviews)
The price is $46
$57 total
includes taxes & fees
Feb 25 - Feb 26

Hotel Museo Spa Casa Santo Domingo
Hotel Museo Spa Casa Santo DomingoBarrio de La Concepción, 1.1 km from Santa Ana
9.2 out of 10, Wonderful, (1,043 reviews)
The price is $266
$337 total
includes taxes & fees
Feb 25 - Feb 26

Hotel Posada de Don Rodrigo Antigua
Hotel Posada de Don Rodrigo AntiguaHistoric Center, 1.5 km from Santa Ana
9.4 out of 10, Exceptional, (688 reviews)
The price is $158
$217 total
includes taxes & fees
Mar 1 - Mar 2

Hotel Posada del Angel
Hotel Posada del Angel1 km from Santa Ana
9.6 out of 10, Exceptional, (285 reviews)

Hotel Casa Carmina
Hotel Casa Carmina1.2 km from Santa Ana
8.8 out of 10, Excellent, (233 reviews)
The price is $162
$198 total
includes taxes & fees
Mar 7 - Mar 8

Las Cruces Boutique Hotel
Las Cruces Boutique HotelHistoric Center, 1.4 km from Santa Ana
9.8 out of 10, Exceptional, (231 reviews)
The price is $250
$305 total
includes taxes & fees
Feb 24 - Feb 25

Meson Panza Verde
Meson Panza Verde1.1 km from Santa Ana
9.2 out of 10, Wonderful, (448 reviews)
The price is $146
$178 total
includes taxes & fees
Mar 8 - Mar 9

Good Hotel Antigua Guatemala, a Member of Design Hotels
Good Hotel Antigua Guatemala, a Member of Design Hotels0.8 km from Santa Ana
9.2 out of 10, Wonderful, (536 reviews)
The price is $177
$215 total
includes taxes & fees
Feb 28 - Mar 1

Mestizo Antigua
Mestizo AntiguaHistoric Center, 1.5 km from Santa Ana
9.4 out of 10, Exceptional, (163 reviews)
The price is $131
$160 total
includes taxes & fees
Feb 25 - Feb 26

Naif Boutique Hotel
Naif Boutique HotelHistoric Center, 1.4 km from Santa Ana
9.0 out of 10, Wonderful, (400 reviews)

Hotel Posada San Vicente
Hotel Posada San VicenteHistoric Center, 1.4 km from Santa Ana
8.0 out of 10, Very Good, (221 reviews)
The price is $53
$64 total
includes taxes & fees
Feb 23 - Feb 24

Hotel Casa Anturio
Hotel Casa AnturioHistoric Center, 1.7 km from Santa Ana
9.2 out of 10, Wonderful, (64 reviews)
The price is $64
$78 total
includes taxes & fees
Mar 18 - Mar 19
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check out reviews of Santa Ana hotels guests love

Wyndham Garden Guatemala City
10/10 Excellent
Find out more about Santa Ana






































































