Hotels in Santa Ana
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7.6 out of 10, Good, (55)
7.6/10
Good
(55)
The price is $25
$25
$28 total
includes taxes & fees
Jan 2 - Jan 3, 2026
6.6 out of 10, (182)
6.6/10
(182)
The price is $29
$29
$32 total
includes taxes & fees
Jan 24 - Jan 25, 2026
9.2 out of 10, Wonderful, (57)
9.2/10
Wonderful
(57)
The price is $83
$83
$91 total
includes taxes & fees
Jan 4 - Jan 5, 2026
7.2 out of 10, Good, (15)
7.2/10
Good
(15)
The price is $59
$59
$92 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Room-sofa Bed Stay Rooftop Pool & Gym, A
Room-sofa Bed Stay Rooftop Pool & Gym, A2.0 star property
Santa Ana
2.0 out of 10, (1)
2.0/10
(1)
The price is $146
$146
$161 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Radisson Hotel Panama Canal
Radisson Hotel Panama Canal4.5 star property
Amador, 2.3 km from Santa Ana
8.4 out of 10, Very Good, (1002)
8.4/10
Very Good
(1002)
The price is $80
$80
$88 total
includes taxes & fees
Jan 30 - Jan 31, 2026
8.8 out of 10, Excellent, (421)
8.8/10
Excellent
(421)
The price is $69
$69
$76 total
includes taxes & fees
Jan 11 - Jan 12, 2026
8.6 out of 10, Excellent, (109)
8.6/10
Excellent
(109)
The price is $74
$74
$82 total
includes taxes & fees
Jan 18 - Jan 19, 2026
7.4 out of 10, Good, (594)
7.4/10
Good
(594)
The price is $65
$65
$72 total
includes taxes & fees
Jan 28 - Jan 29, 2026
8.8 out of 10, Excellent, (276)
8.8/10
Excellent
(276)
9.4 out of 10, Exceptional, (258)
9.4/10
Exceptional
(258)
The price is $142
$142
$156 total
includes taxes & fees
Jan 4 - Jan 5, 2026
9.2 out of 10, Wonderful, (1013)
9.2/10
Wonderful
(1013)
The price is $82
$82
$90 total
includes taxes & fees
Jan 28 - Jan 29, 2026
9.0 out of 10, Wonderful, (4737)
9.0/10
Wonderful
(4737)
The price is $122
$122
$135 total
includes taxes & fees
Jan 12 - Jan 13, 2026
8.2 out of 10, Very Good, (914)
8.2/10
Very Good
(914)
The price is $51
$51
$56 total
includes taxes & fees
Jan 2 - Jan 3, 2026
9.0 out of 10, Wonderful, (1001)
9.0/10
Wonderful
(1001)
The price is $152
$152
$167 total
includes taxes & fees
Jan 30 - Jan 31, 2026
6.6 out of 10, (221)
6.6/10
(221)
The price is $24
$24
$27 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Hyatt Regency Panama City
Hyatt Regency Panama City4.5 star property
Campo Alegre, 3.3 km from Santa Ana
10.0 out of 10, Exceptional, (145)
10/10
Exceptional
(145)
The price is $157
$157
$172 total
includes taxes & fees
Jan 4 - Jan 5, 2026
7.6 out of 10, Good, (129)
7.6/10
Good
(129)
The price is $30
$30
$33 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Amarla Boutique Hotel Casco Viejo
Amarla Boutique Hotel Casco Viejo3.0 star property
San Felipe, 0.9 km from Santa Ana
9.6 out of 10, Exceptional, (108)
9.6/10
Exceptional
(108)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
When is the best time to visit Santa Ana?
When is the best time to visit Santa Ana?Our prices for hotels in Santa Ana are cheapest in September
When is the best time to visit Santa Ana?
When is the best time to visit Santa Ana?
Our prices for hotels in Santa Ana are cheapest in September
Price trends for hotels in Santa Ana
Pricing is based on two traveler single night rates
Currently viewing crowd sizes and weather for December.
Typical weather for Panama City
December
High crowds
High 29°C / low 24°C. Cloudy most days.
View properties in December 29°
December, High crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Cloudy most days.
24°
30°
January, Moderate crowds, average high temperature 30 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
30°
February, High crowds, average high temperature 30 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
31°
March, High crowds, average high temperature 31 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
31°
April, Low crowds, average high temperature 31 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
24°
30°
May, Low crowds, average high temperature 30 degrees Celsius, average low temperature 25 degrees Celsius. Rainy most days.
25°
29°
June, Low crowds, average high temperature 29 degrees Celsius, average low temperature 25 degrees Celsius. Rainy most days.
25°
29°
July, High crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
August, Moderate crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
September, Low crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
October, Moderate crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
29°
November, Moderate crowds, average high temperature 29 degrees Celsius, average low temperature 24 degrees Celsius. Rainy most days.
24°
Monthly weather averages (˚C)
Check out reviews of Santa Ana hotels guests love
Megapolis Hotel Panamá
10/10 Excellent
"Check in took over an hour! "
Crowne Plaza Panama Airport by IHG
10/10 Excellent
"The room was clean and had a good view of Panama which I appreciated. Although close to the airport, I was not unduly aware of aircraft flying overhead. I also was not disturbed by noise from others in the hotel. The breakfast buffet had a wide choice of dishes."
Hyatt Regency Panama City
10/10 Excellent
"The service was top notch. The room was very clean and the property was well maintained and in great conditions. The breakfast buffet was excellent. "
Plaza Paitilla Inn Hotel
10/10 Excellent
"Excelente todo! Ubicación, atención… limpieza, instalaciones… todo espectacular!!!!!"
Principe Hotel and Suites
10/10 Excellent
"This is probably the 20th time I've stayed here. Its always exactly what we need."
Las Americas Golden Tower Panama
10/10 Excellent
"Great hotel in Panama for both short and long stays, with super friendly, warm, and helpful staff who bring a lot of positive energy to the experience, and the colorful design makes the place feel lively and welcoming. I ended up here unexpectedly after getting stuck in Panama due to visa issues, and I was really lucky to find a hotel that recognized my VIP status, checked me in very early in the morning, and supported me when I needed it. Communication was easy since most of the staff speak some English, breakfast offered a nice mix of local and international options, and overall service was excellent. There’s still some room for improvement in room maintenance (like a few lights not working and the desk chair needing replacement), but the room itself was very spacious with great city views."
W Panama
10/10 Excellent
"staff and food are amazing "
Dreams Playa Bonita Panama - All Inclusive
10/10 Excellent
"Room was very nice, staff couldn't be friendlier, they were super nice 👍 "
Novotel Panama City
10/10 Excellent
"The hotel was very nice and the staff was great."
Find out more about Santa Ana