Hotels in Santa Cruz

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Apr 11 - Apr 12
Tomorrow
Apr 12 - Apr 13
Next weekend
Apr 17 - Apr 19
In two weeks
Apr 24 - Apr 26

Where to stay in Santa Cruz?

Outdoor pool
Sun Hotel
Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (361 reviews)
  • cleanliness
    Santa Cruz hotel with airport shuttle, pool, and spa treatments awaits your stay.
The price is $97
$97 total
Apr 12 - Apr 13
Sun Hotel
Standard Suite, 1 Queen Bed | Hypo-allergenic bedding, down comforters, desk, laptop workspace
Equipetrol Suites Apart Hotel
Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (13 reviews)
  • cleanliness
    Enjoy a central stay with kitchenette-equipped suites near Cine Center.
The price is $50
$50 total
Apr 12 - Apr 13
Equipetrol Suites Apart Hotel
Outdoor pool
Mirador del Cielo
Mirador del Cielo
3.0 star property
Santa Cruz
4.0 out of 10, (1 review)
The price is $25
$25 total
Apr 12 - Apr 13
Mirador del Cielo
Seasonal outdoor pool
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (365 reviews)
  • cleanliness
    Enjoy luxury in this Santa Cruz hotel with 2 restaurants and poolside bar.
The price is $131
$131 total
May 8 - May 9
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Bar (on property)
Terranova Suites
Terranova Suites
3.5 star property
Santa Cruz
8.0 out of 10, Very Good, (90 reviews)
  • cleanliness
    Experience tranquility in Santa Cruz with a refreshing outdoor pool and premium comforts.
The price is $52
$52 total
Apr 13 - Apr 14
Terranova Suites
Outdoor pool, pool umbrellas, sun loungers
Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (227 reviews)
  • cleanliness
    Admire Bolivian cityscape from a rooftop terrace with poolside views and spa access.
The price is $119
$119 total
Apr 12 - Apr 13
Marriott Santa Cruz de la Sierra Hotel
Dining room
Hotel BY Armonia SCZ
Hotel BY Armonia SCZ
3.0 star property
Santa Cruz
8.4 out of 10, Very Good, (7 reviews)
  • cleanliness
    Colonial-style hotel with outdoor pool, sauna, and complimentary perks in Santa Cruz.
The price is $85
$85 total
Apr 12 - Apr 13
Hotel BY Armonia SCZ
Outdoor pool, sun loungers
Hotel Cortez
Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (132 reviews)
The price is $138
$138 total
Apr 12 - Apr 13
Hotel Cortez
Premium Room, 1 Queen Bed, Bathtub | Minibar, in-room safe, individually decorated, individually furnished
Cosmopolitano Hotel Boutique
Cosmopolitano Hotel Boutique
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (128 reviews)
  • cleanliness
    Poolside relaxation and cultural attractions await at this boutique Santa Cruz hotel.
The price is $71
$71 total
Apr 18 - Apr 19
Cosmopolitano Hotel Boutique
Living area
Posada Express Fast Check
Posada Express Fast Check
3.0 star property
Santa Cruz
6.8 out of 10, (5 reviews)
  • cleanliness
    Modern inn in Santa Cruz offers a comfortable stay, just minutes from Play Land.
The price is $50
$55 total
Apr 12 - Apr 13
Posada Express Fast Check
Reception
Camino Real Hotel
Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (423 reviews)
  • cleanliness
    Experience luxurious comfort close to Santa Cruz's top attractions and amenities.
The price is $130
$130 total
May 5 - May 6
Camino Real Hotel
Outdoor pool, open 9:00 AM to 8:00 PM, sun loungers
Premium Suites Deluxe Aparthotel Equipetrol
Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (92 reviews)
The price is $39
$39 total
Apr 13 - Apr 14
Premium Suites Deluxe Aparthotel Equipetrol
Exterior
Surbackpackers
Surbackpackers
3.0 star property
Santa Cruz
The price is $23
$23 total
Apr 12 - Apr 13
Surbackpackers
Junior Room, 1 King Bed | Egyptian cotton sheets, premium bedding, pillowtop beds, minibar
HOTEL OSHO
HOTEL OSHO
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (48 reviews)
  • cleanliness
    Rejuvenate in a tranquil spa hotel with pool oasis near Santa Cruz's cultural heart.
The price is $55
$55 total
Apr 22 - Apr 23
HOTEL OSHO
View from property
Hotel Continental Park
Hotel Continental Park
3.0 star property
Santa Cruz
8.8 out of 10, Excellent, (25 reviews)
  • cleanliness
    Explore Bolivia with free breakfast and an outdoor pool near Guarani art center.
The price is $69
$69 total
Apr 12 - Apr 13
Hotel Continental Park
Massages
Swissôtel Santa Cruz De La Sierra
Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (87 reviews)
  • cleanliness
    Luxury oasis in Santa Cruz with spa treatments and poolside relaxation.
The price is $148
$148 total
Apr 26 - Apr 27
Swissôtel Santa Cruz De La Sierra
Double Room, 1 Queen Bed | Premium bedding, down comforters, minibar, blackout drapes
Hotel G
Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (106 reviews)
  • cleanliness
    Hotel G in Santa Cruz offers comfortable accommodations near popular attractions.
The price is $36
$36 total
May 10 - May 11
Hotel G
Outdoor pool
AMERICA APARTMENTS
AMERICA APARTMENTS
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
  • cleanliness
    Cozy Santa Cruz apartments with outdoor pool and private patios.
The price is $55
$55 total
Apr 12 - Apr 13
AMERICA APARTMENTS
Lobby sitting area
Hotel Arenal
Hotel Arenal
3.5 star property
Santa Cruz
7.6 out of 10, Good, (62 reviews)
  • cleanliness
    Lush pool oasis in Santa Cruz with massage services and fitness amenities nearby.
The price is $60
$60 total
Apr 12 - Apr 13
Hotel Arenal
Reception
Urban Suites
Urban Suites
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
  • cleanliness
    Tranquil urban escape with a refreshing pool in the heart of Santa Cruz.
The price is $55
$55 total
May 3 - May 4
Urban Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Get last-minute hotel deals in Santa Cruz and save more

Sign in to unlock great savings.
Showing deals for:Apr 17 - Apr 19
Lobby sitting area
Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (110 reviews)
The price is $118
per night
$236 total
MOD
Sign in for extra savings
Novotel Santa Cruz De La Sierra
Showing deals for:May 11 - May 12
Premium Room, 1 Queen Bed, Bathtub | Minibar, in-room safe, individually decorated, individually furnished
Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (128 reviews)
$21 off
The price is $85
per night
$85 total
Cosmopolitano Hotel Boutique

Check out hotels with a pool in Santa Cruz

Outdoor pool
Mirador del Cielo

Mirador del Cielo

Mirador del Cielo
3.0 star property
Santa Cruz
4.0 out of 10, (1)
The price is $25
$25 total
Apr 12 - Apr 13
Mirador del Cielo
View all properties

You may also like hotels with spas in Santa Cruz

Outdoor pool, pool umbrellas, sun loungers
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (227)
The price is $119
$119 total
Apr 12 - Apr 13
Marriott Santa Cruz de la Sierra Hotel
View all properties

You can also stay at pet-friendly hotels in Santa Cruz

Outdoor pool
AMERICA APARTMENTS

AMERICA APARTMENTS

AMERICA APARTMENTS
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1)
The price is $55
$55 total
Apr 12 - Apr 13
AMERICA APARTMENTS
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

When is the best time to visit Santa Cruz?

Our prices for hotels in Santa Cruz are cheapest in February
Price trends for hotels in Santa Cruz
Pricing is based on two traveler single night rates
View properties in April
Currently viewing crowd sizes and weather for April.
Typical weather for Santa Cruz
April
High 28°C / low 20°C. Sunny most days.
View properties in April
28°
weather_sun
April, no crowd data, average high temperature 28 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
25°
weather_sun
May, no crowd data, average high temperature 25 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
18°
24°
weather_sun
June, no crowd data, average high temperature 24 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
25°
weather_sun
July, no crowd data, average high temperature 25 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
28°
weather_sun
August, no crowd data, average high temperature 28 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
18°
31°
weather_sun
September, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
32°
weather_sun
October, no crowd data, average high temperature 32 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
22°
32°
weather_sun
November, no crowd data, average high temperature 32 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
22°
31°
weather_sun
December, no crowd data, average high temperature 31 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
22°
31°
weather_sun
January, no crowd data, average high temperature 31 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
22°
29°
weather_cloudy
February, no crowd data, average high temperature 29 degrees Celsius, average low temperature 22 degrees Celsius. Cloudy most days.
22°
29°
weather_sun
March, no crowd data, average high temperature 29 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
Monthly weather averages (˚C)

Top neighborhoods in Santa Cruz

Top landmarks in Santa Cruz

Plaza 24 de Septiembre

4.4/5 (164 reviews)
The heart of Santa Cruz buzzes with locals sipping coffee under palms at Plaza 24 de Septiembre. Climb the Cathedral's bell tower for stunning city views while street performers create the soundtrack to your visit.
See properties

San Lorenzo Cathedral

4.5/5 (84 reviews)
Santa Cruz's San Lorenzo Cathedral captivates with its neoclassical grandeur and towering spires. Climb the bell tower at sunset for panoramic views and enjoy local musicians in the vibrant plaza below.
See properties

Learn more about Santa Cruz

Santa Cruz is applauded for its cultural attractions such as Cine Center and Sacred Art Museum.

See all hotels in Santa Cruz

Check out reviews of Santa Cruz hotels guests love

Prince Hotel

Prince Hotel

10/10 Excellent
"Very inexpensive and clean "
Carlos 7-night trip
Posted 19 hours ago
Prince Hotel

Frequently asked questions

What hotels do travelers recommend in Santa Cruz?
Guests like Camino Real Hotel, Ibis Santa Cruz DE LA Sierra and Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel.
Where can I find free parking at my hotel in Santa Cruz?
These hotels offer the perk of free parking: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Hotel LP Equipetrol and Swissôtel Santa Cruz De La Sierra. There are 8 options you may want to check out on our site.
Can I book refundable hotels in Santa Cruz?
If you want the flexibility to change your plans to Santa Cruz, most accommodations offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Santa Cruz if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, browse our selection of 21 vacation homes. In addition, you can choose from 182 apartments.
What will the weather in Santa Cruz be like during my trip?
Santa Cruz is a great place to visit to enjoy the sunshine any time of year with an average temp of 70°F.
Why should I book my Santa Cruz accommodation with Hotels.com?
There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.