Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
December, Low crowds, average high temperature 7 degrees Celsius, average low temperature 0 degrees Celsius. Partly sunny.
0°
4°
weather_cloudy
January, Low crowds, average high temperature 4 degrees Celsius, average low temperature -4 degrees Celsius. Cloudy most days.
-4°
6°
weather_partly_sunny
February, Low crowds, average high temperature 6 degrees Celsius, average low temperature -3 degrees Celsius. Partly sunny.
-3°
13°
weather_partly_sunny
March, Moderate crowds, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Partly sunny.
4°
19°
weather_sun
April, Moderate crowds, average high temperature 19 degrees Celsius, average low temperature 8 degrees Celsius. Sunny most days.
8°
24°
weather_sun
May, High crowds, average high temperature 24 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
14°
30°
weather_sun
June, High crowds, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
31°
weather_sun
July, High crowds, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
30°
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August, High crowds, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
27°
weather_sun
September, Moderate crowds, average high temperature 27 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
20°
weather_sun
October, Moderate crowds, average high temperature 20 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
13°
weather_partly_sunny
November, Low crowds, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Partly sunny.
4°
Monthly weather averages (˚C)
Top landmarks in Wydown Skinker
Mildred Lane Kemper Art Museum
Mildred Lane Kemper Art Museum is just one of the attractions in Wydown Skinker, St. Louis so you might want to stop by during your trip. If you want to experience more of the culture St. Louis has to offer, head to Washington University in St. Louis, St. Louis Art Museum, and St. Louis Zoo.
"This was absolutely great! Wish I could have stayed longer. A true luxury feel. Wish parking a little better, but that is what happened you are in a true older fine hotel. Would definitely stay here again!"
"Hotel was very clean! They have a lot of extras like the kick back! We basically had dinner every night. Staff was friendly and kind! Its location was great and easy to access. "
"If you have ever wanted to step inside a Wes Anderson film—complete with the perfect symmetry, whimsical color palettes, and that distinct feeling of curated reality—the 21c Museum Hotel in St. Louis is it.
The rooms are the true showstopper. Opening the door felt less like entering a hotel room and more like being transported to a high-end, 1960s Mad Men-inspired apartment. The attention to detail is staggering. The aesthetic is a masterclass in mid-century modern design, featuring rich wood paneling, deep jewel tones, and opulent finishings that scream Don Draper excellence. The furniture feels substantial and curated, not mass-produced, with tactile fabrics and silhouettes that anchor the space in that golden era of design.
And then, there is the bathroom.
I can say, without hyperbole, that this is the best bathroom of any hotel we’ve ever stayed at. It is an absolute sanctuary. The design continues that opulent, retro-modern theme with stunning tiling and heavy, brushed brass fixtures that feel incredible to use. It’s spacious and bright, featuring a vanity area that actually allows you to spread out. The shower pressure was perfect, and the high-end amenities (Malin+Goetz) were the cherry on top. It’s the kind of bathroom that makes you want to renovate your own home the second you leave.
The 21c St. Louis manages to thread the needle between a serious art gallery and a cozy, nostalgic retreat."