Hotels in Seneca

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Check prices for these dates

Tonight
Oct 26 - Oct 27
Tomorrow
Oct 27 - Oct 28
This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Where to stay in Seneca?

An outdoor patio area with a fire pit, seating, and string lights.
A food court with a beverage display, seating area, and a Clemson University sign.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern restaurant with a central counter, seating area, and a TV displaying news.

1. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
$102
$112 total
includes taxes & fees
Nov 19 - Nov 20
Tru by Hilton Seneca Clemson
A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lobby with a reception desk, seating area, and a vending machine.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

2. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
$120
$132 total
includes taxes & fees
Nov 1 - Nov 2
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

3. Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
$94
$103 total
includes taxes & fees
Oct 28 - Oct 29
Best Western Seneca-Clemson
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A reception area with a counter, chairs, and a patterned rug.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

4. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
$135
$149 total
includes taxes & fees
Nov 24 - Nov 25
Hampton Inn & Suites Seneca-Clemson Area
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

5. Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
$85
$99 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn Seneca US-123
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.
A spacious dining area with a long wooden table and patterned upholstered chairs.

6. Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
$109
$135 total
includes taxes & fees
Oct 27 - Oct 28
Lakeside Lodge Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A Days Inn reception area with a view of the parking lot and trees.
A swimming pool with lounge chairs and a fence, surrounded by trees.

7. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
$75
$82 total
includes taxes & fees
Oct 28 - Oct 29
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A cabin in a forest with a small deck and outdoor seating area.
A forested area with a cabin and a vehicle parked on a gravel path.
A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.

8. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
$93
$146 total
includes taxes & fees
Nov 3 - Nov 4
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A modern bar area with a menu board, bar stools, and a countertop with various items.
A modern dining area with a bar, bar stools, and a patterned rug.
An outdoor patio with a circular fire pit surrounded by wicker furniture and a pergola overhead.
A Courtyard Marriott hotel with a brick facade, multiple floors, and a covered entrance area.

9. Courtyard Marriott Clemson

Courtyard Marriott Clemson
Clemson
$103
$115 total
includes taxes & fees
Nov 22 - Nov 23
Courtyard Marriott Clemson
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.
A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.
A bar area with a counter, multiple chairs, and a display of bottles and glasses.
A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.

10. The Abernathy of Clemson

The Abernathy of Clemson
Clemson
$152
$169 total
includes taxes & fees
Nov 16 - Nov 17
The Abernathy of Clemson
A modern kitchen area with a bar counter and seating.
A Hampton Inn with a modern design, featuring a prominent entrance and outdoor seating area.
A vending area with snacks and beverages, including chips and soda.
A modern living room with a grey sofa, purple and orange cushions, a coffee table with magazines, and a large window with patterned curtains.

11. Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
Clemson
$97
$108 total
includes taxes & fees
Nov 22 - Nov 23
Hampton Inn Clemson-University Area
A golf course with a water body, trees, and a distant view of a bridge.
A large, curved swimming pool with lounge chairs and umbrellas, surrounded by landscaped areas and a building in the background.
An outdoor patio with tables and chairs, surrounded by trees and a view of a body of water.
A modern building with a central entrance, surrounded by a well-maintained lawn and trees.

12. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
Clemson
$149
$165 total
includes taxes & fees
Oct 27 - Oct 28
Clemson University's James F. Martin Inn
A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.
A dining area with a brick floor, wooden tables, and chairs, a kitchen counter with appliances, and large windows offering a view of the outside.
A hotel room with two beds, a desk, a television, and a clock on the wall.
A tiger mascot holding a sign with "HOWARD'S ROCK" text, a staircase, and a desk with a computer.

13. Inn @ Clemson

Inn @ Clemson
Clemson
$89
$99 total
includes taxes & fees
Oct 27 - Oct 28
Inn @ Clemson
A modern kitchen with a microwave, coffee maker, and bar stools.
A hotel room with a large flat-screen TV mounted on the wall, a desk with a chair, a bedside table, a lamp, and a wardrobe.
A hotel lobby with a reception desk, a large tiger mural, a TV, and a seating area with a blue sofa.
A hotel hallway with a carpeted floor, light-colored walls, and doors on both sides.

14. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
Clemson
$105
$117 total
includes taxes & fees
Nov 15 - Nov 16
Comfort Inn & Suites Clemson - University Area
A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.
A conference room with tables and chairs, a projector screen, and a carpeted floor.
A hotel breakfast area with a self-serve station, including a refrigerator, coffee machine, and fruit display.
A hotel room with a bed, a desk, a television, a lamp, and a sofa.

15. Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
Clemson
$129
$143 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express & Suites Clemson by IHG
A kitchen with a coffee maker, microwave, and refrigerator.
A red brick building with a white porch and columns, a door, and windows.
A hotel room with a large bed, a bedside table, a nightstand, and a wall-mounted lamp.
A hotel room with a bed, a desk with a chair, a television, a small table, and a microwave.

16. Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
Walhalla
$80
$89 total
includes taxes & fees
Nov 25 - Nov 26
Rodeway Inn & Suites Walhalla
A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.
A lobby with seating areas, a reception desk, and a patterned wall.
A spacious indoor area with multiple levels of balconies, seating areas, and a central open space.
A spacious indoor area with multiple seating arrangements, a ping pong table, and a bar area with purple accents.

17. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
Clemson
$105
$117 total
includes taxes & fees
Oct 28 - Oct 29
Best Western Plus Clemson Hotel & Conference Center
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.
A modern bar area with a wooden ceiling, green bar stools, and a bar counter.
An outdoor patio with wicker furniture, a round table, and a fountain.

18. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
$209
$232 total
includes taxes & fees
Oct 27 - Oct 28
The Shepherd Hotel Downtown Clemson
A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.
A gazebo with a tiled roof and wooden pillars, surrounded by a fence and potted plants.
A hotel room with two beds, a desk, a chair, a TV, and a painting on the wall.
A reception desk with a vase of flowers, framed pictures, and a printer.

19. Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson
Clemson
$80
$89 total
includes taxes & fees
Oct 27 - Oct 28
Days Inn by Wyndham Clemson
A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.
Private kitchen
A room with wooden sliding doors, a small black table with a potted plant, and a circular sign with the words "stay awhile".
A bedroom with a bed, bedside tables, a nightstand, a wooden floor, a door, and a wall-mounted shelf.

20. Clemson Memorabilia House

Clemson Memorabilia House
Clemson
$89
$238 total
includes taxes & fees
Nov 1 - Nov 2
Clemson Memorabilia House
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A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
$94
per night
$110 total
includes taxes & fees
Quality Inn Seneca US-123
A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lobby with a reception desk, seating area, and a vending machine.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
$139
per night
$153 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
$110
per night
$121 total
includes taxes & fees
Best Western Seneca-Clemson
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A reception area with a counter, chairs, and a patterned rug.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
$155
per night
$171 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A Days Inn reception area with a view of the parking lot and trees.
A swimming pool with lounge chairs and a fence, surrounded by trees.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
$94
per night
$103 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.
A spacious dining area with a long wooden table and patterned upholstered chairs.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
$109
per night
$135 total
includes taxes & fees
Lakeside Lodge Clemson
An outdoor patio area with a fire pit, seating, and string lights.
A food court with a beverage display, seating area, and a Clemson University sign.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern restaurant with a central counter, seating area, and a TV displaying news.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
$147
per night
$162 total
includes taxes & fees
Tru by Hilton Seneca Clemson
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A cabin in a forest with a small deck and outdoor seating area.
A forested area with a cabin and a vehicle parked on a gravel path.
A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
$114
per night
$169 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
$94
per night
$110 total
includes taxes & fees
Quality Inn Seneca US-123
A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lobby with a reception desk, seating area, and a vending machine.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
$139
per night
$153 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A reception area with a counter, chairs, and a patterned rug.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
$155
per night
$171 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
$110
per night
$121 total
includes taxes & fees
Best Western Seneca-Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A Days Inn reception area with a view of the parking lot and trees.
A swimming pool with lounge chairs and a fence, surrounded by trees.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
$9 off
$82
per night
$90 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.
A spacious dining area with a long wooden table and patterned upholstered chairs.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
$109
per night
$135 total
includes taxes & fees
Lakeside Lodge Clemson
An outdoor patio area with a fire pit, seating, and string lights.
A food court with a beverage display, seating area, and a Clemson University sign.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern restaurant with a central counter, seating area, and a TV displaying news.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
$139
per night
$153 total
includes taxes & fees
Tru by Hilton Seneca Clemson
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A cabin in a forest with a small deck and outdoor seating area.
A forested area with a cabin and a vehicle parked on a gravel path.
A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
$114
per night
$169 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.
A spacious dining area with a long wooden table and patterned upholstered chairs.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
$109
per night
$271 total
includes taxes & fees
Lakeside Lodge Clemson
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
$105
per night
$232 total
includes taxes & fees
Best Western Seneca-Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
$85
per night
$199 total
includes taxes & fees
Quality Inn Seneca US-123
An outdoor patio area with a fire pit, seating, and string lights.
A food court with a beverage display, seating area, and a Clemson University sign.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern restaurant with a central counter, seating area, and a TV displaying news.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
$116
per night
$254 total
includes taxes & fees
Tru by Hilton Seneca Clemson
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A reception area with a counter, chairs, and a patterned rug.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
$182
per night
$401 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A Days Inn reception area with a view of the parking lot and trees.
A swimming pool with lounge chairs and a fence, surrounded by trees.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
$27 off
$77
per night
$170 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A cabin in a forest with a small deck and outdoor seating area.
A forested area with a cabin and a vehicle parked on a gravel path.
A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
$60 off
$169
per night
$460 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A modern kitchen with wooden cabinets, a stainless steel dishwasher, and a granite countertop.
A gym with various exercise equipment, including treadmills and weight machines, and a large mirror reflecting the space.
A rectangular swimming pool with a stone wall on one side and a wooden deck with lounge chairs on the other.
A white door with a glass panel, a wooden deck, and a house in the background.

Condo on Lake Hartwell 3 Mi to Clemson Stadium

Condo on Lake Hartwell 3 Mi to Clemson Stadium
Seneca
$176
per night
$622 total
includes taxes & fees
Condo on Lake Hartwell 3 Mi to Clemson Stadium
A cozy bedroom with a bed, a nightstand, a lamp, a small table, a window, and a Christmas tree.
A kitchen with wooden cabinets, a microwave, a stove, and a refrigerator.
A home interior with a metal shelf unit displaying various items, a hallway with wooden flooring, and a door leading to another room.
A living room with a sofa, ottoman, and a leather chair with a 'Family' pillow. There is a ceiling fan, a plant, and a window with curtains.

8 Mi to Clemson: Peaceful Family Home w/ Yard

8 Mi to Clemson: Peaceful Family Home w/ Yard
Seneca
$212
per night
$668 total
includes taxes & fees
8 Mi to Clemson: Peaceful Family Home w/ Yard
A clear lake with a rocky shoreline and a tree branch overhanging the water.
A two-story building with a garage, a staircase, and a view of the water.
A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a dishwasher.
A wooden deck with a view of a forested area and a building with a sloped roof.

6 Mi to South Cove Boat Ramp! Lake Keowee Escape

6 Mi to South Cove Boat Ramp! Lake Keowee Escape
Seneca
$215
per night
$704 total
includes taxes & fees
6 Mi to South Cove Boat Ramp! Lake Keowee Escape
A round wooden table with a flower vase and a WiFi sign, surrounded by blue cushioned benches, in a room with large windows and a hanging light fixture.
A two-story house with a covered porch, surrounded by a well-maintained lawn and trees.
Interior
A covered porch with a ceiling fan, a wooden bench, a cushioned sofa, and a small table.

Screened Patio & Yard: Clemson Weekends/lakes Stay

Screened Patio & Yard: Clemson Weekends/lakes Stay
Seneca
$242
per night
$835 total
includes taxes & fees
Screened Patio & Yard: Clemson Weekends/lakes Stay
A spacious living room with a fireplace, comfortable seating, and large windows.
A bedroom with a bed, two chairs, a window with curtains, a ceiling light, and a door.
A two-story house with a balcony, a front porch, and a well-maintained lawn.
A modern kitchen with a dishwasher, coffee maker, and a dining area with a round table and chairs.

Clemson Basecamp! Lake Keowee Hideaway

Clemson Basecamp! Lake Keowee Hideaway
Seneca
$340
per night
$1,125 total
includes taxes & fees
Clemson Basecamp! Lake Keowee Hideaway
A bedroom with a wooden bed, a nightstand, a chair, and a view of the outside through a window.
A spacious kitchen with wooden flooring, white cabinets, and a dining area with a table and chairs.
A modern kitchen with stainless steel appliances, white cabinetry, and a central island.
Interior

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar
Seneca
$181
per night
$634 total
includes taxes & fees
Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar
A house with a front porch, a door, and two chairs.
A living room with a sofa, a coffee table, a television, a lamp, a bookshelf, and a ceiling fan.
A two-story house with a garage, surrounded by trees and a well-maintained lawn.
A dining area with a wooden table, chairs, a ceiling fan, and a view of the kitchen through a window.

Clemson Weekends 3 Mi From Memorial Stadium

Clemson Weekends 3 Mi From Memorial Stadium
Seneca
$248
per night
$848 total
includes taxes & fees
Clemson Weekends 3 Mi From Memorial Stadium
A wooden deck with a view of a forest and a lake.
A deck with outdoor seating overlooking a forested area and a body of water.
A modern kitchen with a large island, a stone fireplace, and a cozy seating area with a view of the outdoors.
A forested campsite with a dirt path, a fire pit, and a lake in the background.

Lake Hartwell Home w/ Dock < 10 Miles to Clemson!

Lake Hartwell Home w/ Dock < 10 Miles to Clemson!
Seneca
$268
per night
$791 total
includes taxes & fees
Lake Hartwell Home w/ Dock < 10 Miles to Clemson!

Check out pet-friendly hotels in Seneca

A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
$85
$99 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn Seneca US-123
An outdoor patio area with a fire pit, seating, and string lights.
A food court with a beverage display, seating area, and a Clemson University sign.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern restaurant with a central counter, seating area, and a TV displaying news.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
$102
$112 total
includes taxes & fees
Nov 19 - Nov 20
Tru by Hilton Seneca Clemson
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.
A spacious dining area with a long wooden table and patterned upholstered chairs.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
$109
$135 total
includes taxes & fees
Oct 27 - Oct 28
Lakeside Lodge Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A Days Inn reception area with a view of the parking lot and trees.
A swimming pool with lounge chairs and a fence, surrounded by trees.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
$75
$82 total
includes taxes & fees
Oct 28 - Oct 29
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A cabin in a forest with a small deck and outdoor seating area.
A forested area with a cabin and a vehicle parked on a gravel path.
A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
$93
$146 total
includes taxes & fees
Nov 3 - Nov 4
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
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You can also stay at hotels with a pool in Seneca

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
$94
$103 total
includes taxes & fees
Oct 28 - Oct 29
Best Western Seneca-Clemson
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A reception area with a counter, chairs, and a patterned rug.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
$135
$149 total
includes taxes & fees
Nov 24 - Nov 25
Hampton Inn & Suites Seneca-Clemson Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.
A spacious dining area with a long wooden table and patterned upholstered chairs.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
$109
$135 total
includes taxes & fees
Oct 27 - Oct 28
Lakeside Lodge Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
$85
$99 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn Seneca US-123
A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lobby with a reception desk, seating area, and a vending machine.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
$120
$132 total
includes taxes & fees
Nov 1 - Nov 2
Fairfield Inn & Suites Seneca Clemson Univ Area
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A Days Inn reception area with a view of the parking lot and trees.
A swimming pool with lounge chairs and a fence, surrounded by trees.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
$75
$82 total
includes taxes & fees
Oct 28 - Oct 29
Days Inn by Wyndham Seneca / Clemson Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our prices for hotels in Seneca are cheapest in December
Price trends for hotels in Seneca
Pricing is based on two traveler single night rates
View properties in October
Typical weather for Seneca
October
High 23°C / low 12°C. Sunny most days.
View properties in October
23°
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17°
6°
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4°
10°
1°
13°
3°
17°
6°
22°
10°
26°
15°
31°
19°
32°
21°
31°
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Monthly weather averages (˚C)

Top neighborhoods in Seneca

A lakeside scene with autumn foliage, a clear sky, and a sunset.
A large lake surrounded by dense forests.

Downtown

Downtown Seneca charms visitors with well-preserved historical buildings that tell the story of its railroad heritage. The tree-lined Ram Cat Alley showcases local history through colorful murals, while the old courthouse square hosts seasonal farmers markets and community events. You can explore the Bertha Lee Strickland Cultural Museum or browse antique shops filled with Southern treasures. Family-owned cafes serve up delicious Southern comfort food like fried green tomatoes and barbecue. Accommodations range from historic bed & breakfasts in Victorian homes to budget-friendly motels. The entire downtown is walkable with wide sidewalks, making it easy to discover this authentic slice of small-town America at your own pace.

A sunset over a lake surrounded by dense forests and residential areas.

Serenity Bay

Lake Keowee beckons from this peaceful coastal retreat nestled in Saxony Forest. Serenity Bay lives up to its name with tree-lined streets perfect for contemplative walks. Nearby Keowee Key Golf Course offers tee times for enthusiasts, while South Beach provides sandy relaxation without the crowds. The natural setting creates an ideal escape for bird watchers and nature photographers. Vacation rentals with weathered wood siding and muted earth tones blend seamlessly into the forest canopy. Getting around requires your own wheels since public transit is limited. The neighborhood trades bustling nightlife for cricket choruses and ocean breezes filtering through pine trees—exactly what makes this hidden gem worth finding.

A sunset over a calm lake with a kayaker and a large tree on the shore.

Pine Ridge Point

Lake Keowee sparkles as the crown jewel of Pine Ridge Point, a peaceful residential haven in Seneca. Waterfront vacation homes nestle among tall pines, offering private docks and stunning views. Visitors spend days swimming in crystal-clear waters, boating across the lake, or simply unwinding on expansive decks beneath Carolina blue skies. This neighborhood is all about authentic lakeside living without commercial distractions. Most travelers cook in well-equipped rental kitchens or drive 15 minutes to Seneca for restaurants. Personal vehicles are essential for getting around, though scenic paths along the shoreline make for perfect evening strolls.

Indian Oaks

Indian Oaks gives you all the peaceful vibes of suburban life with none of the tourist chaos. This leafy neighborhood in Seneca lets you live like a local under a canopy of mature oak trees. The curved streets and manicured lawns create a park-like setting that's perfect for morning walks. Lake Keowee is just a short drive away when you need a water fix. You'll need wheels to get around since public transit is limited and restaurants aren't within walking distance. Most visitors stay in vacation rental homes with private yards and driveways. The neighborhood gets incredibly quiet after dark—ideal for travelers who want to experience authentic suburban living while having Seneca's attractions nearby.

Top landmarks in Seneca

A waterfall surrounded by autumn foliage.

High Falls County Park

High Falls County Park is worth a visit, located 7.8 mi (12.5 km) from central Seneca.
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A grassy field with yellow flowers and trees in the foreground, with mountains in the background.

Blue Ridge Field

Blue Ridge Field is worth a visit, located 0.8 mi (1.2 km) from central Seneca.
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World of Energy

If museums are on your list of things to see in Seneca, then you might want to head to World of Energy. If you want to experience more of the culture Seneca has to offer, head to Lake Keowee, Keowee Key Golf Course, and High Falls County Park.
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Highpointe Field

Highpointe Field is worth a visit, located 5.6 mi (8.9 km) from central Seneca.
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South Cove Park

South Cove Park is worth a visit, located 2 mi (3.3 km) from central Seneca.
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Highpointe Lower Field

Highpointe Lower Field is worth a visit, located 5.7 mi (9.1 km) from central Seneca.
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Oconee County Library Seneca Branch

Oconee County Library Seneca Branch is worth a pic or two when discovering Downtown.
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Friendship Recreation Area

Friendship Recreation Area is worth a visit, located 6.5 mi (10.5 km) from central Seneca.
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Learn more about Seneca

Between the crystal waters of Lake Keowee and the misty cascade of Isaqueena Falls lies a playground for outdoor enthusiasts. Kayak across the lake while keeping an eye out for bald eagles soaring overhead and blue herons stalking the shallows. The lush forests of Oconee State Park offer hiking trails for every skill level, with shade-dappled paths winding through ancient trees. Twin Lakes Recreation Area provides family-friendly spots to picnic after a morning on the water. Dog owners shouldn't miss The Pier Dog Park, where four-legged friends can splash along the shoreline. After a day of adventure, the coffeehouses in the historic downtown offer the perfect place to recharge while planning tomorrow's excursion to Keowee Key Golf Course or Lake Hartwell.

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A sunset over a lake surrounded by dense forests and residential areas.

Check out reviews of Seneca hotels guests love

Best Western Seneca-Clemson

Best Western Seneca-Clemson

10/10 Excellent
"update rooms"
Valerie 2-night trip
Posted 15 hours ago
Best Western Seneca-Clemson
Lakeside Lodge Clemson

Lakeside Lodge Clemson

10/10 Excellent
"Absolutely amazing! We can't wait to go back!! The bar staff was top notch!!"
Lakin 3-night trip
Posted 2 days ago
Lakeside Lodge Clemson
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

10/10 Excellent
"Room was clean and staff was friendly and helpful."
Sasha 1-night trip
Posted 6 days ago
Hampton Inn & Suites Seneca-Clemson Area
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

8/10 Good
"A nice variety for breakfast."
Angela 2-night trip
Posted 8 days ago
Fairfield Inn & Suites Seneca Clemson Univ Area
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

10/10 Excellent
"The staff were very friendly and everything was nice and clean! A great selection for breakfast!"
Alexis 2-night trip
Posted 11 days ago
Tru by Hilton Seneca Clemson

Frequently asked questions

What accommodations do travelers like in Seneca?
Guests like Lakeside Lodge Clemson, Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy and Quality Inn Seneca US-123.
Can I book refundable accommodations in Seneca?
If you want the flexibility to change your travel plans to Seneca, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Seneca if I want a budget-friendly accommodation?
Lakeside Lodge Clemson, Quality Inn Seneca US-123 and Hampton Inn & Suites Seneca-Clemson Area are a few accommodations you might want to consider that'll save you money.
Where can I stay in Seneca if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, review our selection of 217 vacation homes. In addition, there are 24 apartments and 13 condos.
What will the weather in Seneca be like during my visit?
The warmest months in Seneca are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 46°F. The rainiest months are December and January.
Why should I book my Seneca hotel with Hotels.com?
There are plenty of reasons to book your Seneca travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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