Hotels in Mesa

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Where to stay in Mesa?

A restaurant interior with wooden beams, antler decorations, and a long wooden bench.

A building with a porch, wooden steps, and two large wheels on the facade.

A bar area with wooden bar stools, a central bar counter, and shelves stocked with bottles and glasses.

A bedroom with a wooden headboard, a bed with a green bedspread, two bedside tables with lamps, and a small wooden desk with a plant.

1. Wagon Wheel Restaurant Bar and Motel

Mesa

$170

$179 total

includes taxes & fees

Sep 10 - Sep 11

A hotel with a swimming pool, lounge chairs, and a view of a mountain.

A formal dining setting with a table set for four, including wine glasses and a vase of red roses.

A house with a covered porch, a stone wall, and a mountain in the background.

A covered porch with white rocking chairs, a wooden barrel, and a view of a mountain.

2. Wine Country Inn Palisade

Palisade

$160

$178 total

includes taxes & fees

Sep 10 - Sep 11

A wooden deck with a view of a forest and a lake.

Two wooden cabins surrounded by a snowy forest.

A cozy cabin interior with a wooden dining table, a sofa, and a kitchen area including a stove and cabinets.

A spacious restaurant with wooden tables and chairs, a chandelier, and a mural on the wall.

3. Grand Mesa Lodge

Cedaredge

$122

$133 total

includes taxes & fees

Sep 14 - Sep 15

A spacious living area with a high ceiling, a wooden coffee table, a leather sofa, and a staircase leading to an upper level.

A spacious living room with a stone fireplace, a leather sofa, a desk with a computer, and a large mirror.

A hotel room with a large bed, a TV, a dresser, and a door.

4. Best Western Grande River Inn & Suites

Clifton

$118

$126 total

includes taxes & fees

Sep 28 - Sep 29

A sign for the Spoke and Vine Motel with a bicycle symbol, set against a mountainous backdrop.

A covered outdoor seating area with wooden benches and a round table.

A bar area with a bicycle wheel decoration, a bar menu, and shelves with bottles and snacks.

A dining area with a wooden table and chairs, a patterned rug, and pendant lighting.

5. Spoke and Vine Motel

Palisade

$161

$179 total

includes taxes & fees

Oct 5 - Oct 6

Two people sitting on chairs outside a building with green doors, one holding a bottle.

A room with a sofa, a dining table, chairs, a potted plant, a wall-mounted plant, and a framed picture.

Two people sitting on a bed with a laptop and a book.

A green door with the number 3, two brown chairs, and a potted plant.

6. The Alpine Motel

Collbran

$122

$131 total

includes taxes & fees

Sep 18 - Sep 19

A reception desk at the Grand River Hotel with a stone wall backdrop and a large illuminated sign.

A cozy living room with a stone accent wall, leather sofa, patterned chairs, and horse-themed artwork.

A Grand River Hotel with a modern design, featuring a prominent entrance and a parking lot.

A cozy living room with a fireplace, leather sofa, and horse-themed artwork.

7. Grand River Hotel

Parachute

$70

$79 total

includes taxes & fees

Sep 11 - Sep 12

A parking lot with a red SUV, a blue truck, and a white car.

A gym with treadmills, weight machines, and exercise balls.

A hotel room with a wooden dining table, chairs, a TV, a desk, and a window with curtains.

A reception area with a wooden counter, a coffee bar, and a large landscape painting on the wall.

8. Western Slope suites

Parachute

$75

$85 total

includes taxes & fees

Sep 10 - Sep 11

A rustic cabin with a garage, surrounded by a gravel driveway, a large tree with yellow leaves, and a rocky cliff in the background.

A patio with two lounge chairs and a wooden table, overlooking a grassy area with autumn foliage and distant mountains.

A modern bedroom with a large bed, a TV mounted on the wall, a bathroom with a shower curtain, and a small seating area with a chair.

A rustic building with a red exterior and white walls, a gravel driveway, and a large tree in front.

9. The Homestead

Palisade

$233

$245 total

includes taxes & fees

Sep 10 - Sep 11

A large indoor swimming pool with a hot tub, surrounded by lounge chairs and a tiled floor.

A hotel room with a large bed, two bedside tables with lamps, a window with curtains, and a view of mountains.

A hotel lobby with a reception desk, seating area, and fireplace.

A Grand Vista Hotel with a covered entrance, multiple windows, and a well-lit facade.

10. Grand Vista Hotel Parachute

Parachute

$84

$95 total

includes taxes & fees

Sep 10 - Sep 11

A rustic interior with a staircase, wooden beams, and potted plants.

A modern building with large windows, a staircase, and a solar panel.

A room with a bed, a desk, a chair, a table, and a view through a glass door to the outside.

A kitchen with wooden cabinets, a large island, stainless steel appliances, and a window providing natural light.

11. Maison de Terre

Cedaredge

$140

$179 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with a wooden floor, a sofa, a small table with a lamp, a bathroom with a bathtub, and a window with curtains.

A breakfast bar with a coffee machine, toaster, and microwave.

A circular fire pit surrounded by a brick border, set in a gravel area with a grassy background.

An indoor swimming pool with a tiled edge, a lifeguard chair, and a door with an exit sign.

12. Stay Wise Inn Cedaredge

Cedaredge

$107

$118 total

includes taxes & fees

Sep 10 - Sep 11

A spacious room with a large window, a red armchair, a wooden desk, and a lamp.

A buffet area with a wooden counter, a glass display case, and a Coca-Cola machine.

A reception desk with a wooden finish, a non-smoking sign, framed certificates on the wall, and a clock.

A hotel room with a bed, a desk with a computer, a mirror, a lamp, and a telephone.

13. Quality Inn Grand Junction near University

Horizon Drive District

$69

$79 total

includes taxes & fees

Oct 5 - Oct 6

A reception desk with a clock, a computer, and a potted plant.

A modern office space with a desk, office chair, and a large landscape painting on the wall.

A corridor with tiled flooring, several round tables with chairs, and a black refrigerator.

A hotel hallway with a patterned carpet, doors on both sides, and a tiled ceiling.

14. Ramada by Wyndham Grand Junction

Horizon Drive District

$70

$80 total

includes taxes & fees

Sep 13 - Sep 14

A breakfast bar with a variety of food items, including fruits, pastries, and dairy products.

A hotel room with two beds, a desk, and a window with curtains.

A hot tub surrounded by lounge chairs and a pool, with a building in the background.

A reception area with a large mural of a desert landscape, two reception desks with modern design, and a patterned wall to the left.

15. La Quinta Inn & Suites by Wyndham Grand Junction

Horizon Drive District

$108

$124 total

includes taxes & fees

Sep 13 - Sep 14

A spacious living area with a staircase, two grey armchairs, a round coffee table, and a view of the outside.

A hotel room with a large bed, a desk, a chair, a small table, and a wall-mounted heater.

An indoor swimming pool with a lifeguard chair, pool ladder, and a seating area with tables and chairs.

A spacious dining area with multiple tables and chairs, a kitchen in the background, and a modern ceiling design.

16. Comfort Inn Grand Junction I-70

Horizon Drive District

$117

$134 total

includes taxes & fees

Oct 5 - Oct 6

A reception area with a wooden reception desk, a framed welcome sign, and a no-smoking sign.

A laundry area with stacked washers and dryers, a window with blinds, and wall-mounted artwork.

A rectangular swimming pool with a blue tiled edge, surrounded by white lounge chairs and a metal fence.

A hotel room with two beds, a nightstand with a lamp, and two framed pictures on the wall.

17. Super 8 by Wyndham Grand Junction Colorado

Horizon Drive District

$61

$70 total

includes taxes & fees

Sep 16 - Sep 17

A hotel room with a bed, a chair, a window with a view of a landscape, and a lamp.

A hotel room with a red accent wall, a sofa, a chair, a small table, and a lamp.

A golf course with a large green, sand bunkers, and a rocky hill in the background.

A white building with a central tower and a smaller attached structure, surrounded by a grassy area and mountains in the background.

18. Holiday Inn & Suites Grand Junction-Airport by IHG

Horizon Drive District

$122

$140 total

includes taxes & fees

Sep 13 - Sep 14

A restaurant with stone walls and large windows, outdoor wooden tables and chairs, and a garden with colorful flowers.

A bar area with a wooden interior, bar stools, and a sign for Cook's Goldblume beer.

An indoor swimming pool with a mural of a desert landscape, a ceiling with skylights, and a seating area with chairs.

A dining area with a wooden table and chairs, a kitchen counter with various items, and a view of trees through large windows.

19. Grand Vista Hotel

Horizon Drive District

$89

$102 total

includes taxes & fees

Oct 4 - Oct 5

An indoor swimming pool with a hot tub, surrounded by white chairs and a brick wall.

A patio area with outdoor seating, a brick building, and a well-maintained lawn.

A bar area with a counter, bar stools, and a television screen.

A modern lounge area with leather armchairs, a round coffee table, and a bookshelf.

20. Clarion Inn Grand Junction

Horizon Drive District

$101

$116 total

includes taxes & fees

Sep 13 - Sep 14

View all properties

Go beyond your typical stay in Mesa

Pet friendly

Pool

Hot tub

Family friendly

Our prices for hotels in Mesa are cheapest in September

Top landmarks in Mesa

Powderhorn Resort

8.6/10 (106 reviews)

Skiers and snowboarders might want to test out the slopes at Powderhorn Resort, a skiing spot located 6.7 mi (10.8 km) from central Mesa.

See properties

Learn more about Mesa

Mesa is well-known for its attractions such as Powderhorn Resort and Grand Mesa National Forest.

See all hotels in Mesa

A leafless tree on a rocky hillside with a vast landscape in the background.

Check out reviews of Mesa hotels guests love

Super 8 by Wyndham Grand Junction Colorado

8/10 Good

"The room was very clean. Beds and pillows were comfortable. Towels were not thick but they were clean. The staff were friendly. Unfortunately, guests that stayed before had zero home training and wrote on furniture and the mirror in permanent marker. The hotel needs some renovating but a clean, decent place to sleep for a night."

Ramada by Wyndham Grand Junction

10/10 Excellent

"Nice place to stay and price good"

Grand Vista Hotel

8/10 Good

"Need to update charging ports not very good access to outlets to plug into"

Grand Vista Hotel Parachute

10/10 Excellent

"Very nice place to stay"

Quality Inn Grand Junction near University

10/10 Excellent

"Standard room. Clean. Great breakfast. 1 night stay."

Wagon Wheel Restaurant Bar and Motel

10/10 Excellent

"Quaint motel in Mesa with friendly staff. Restaurant and bar was great!"

Powderhorn Lodging

10/10 Excellent

"The tiny homes were a perfect place to recconet with family."

Frequently asked questions

What accommodations do travelers like in Mesa?

Guests like Wagon Wheel Restaurant Bar and Motel and Powderhorn Lodging.

Can I book a refundable hotel in Mesa?

If you need the flexibility to change your travel plans to Mesa, most properties offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where can I stay in Mesa if I want a vacation home instead of a hotel?

Browse 10 vacation homes on our site. You can also book one of the 13 cabins for your stay.

What will the weather in Mesa be like during my vacation?

July and August are typically the warmest months in Mesa when the average temp is 69°F. January and December are the coldest months when the average temperature is 27°F. March and December are the months with the most rain.

Why should I book my Mesa hotel with Hotels.com?

There are lots of reasons to book your Mesa trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring

More ways to book

Book Hotels in Mesa on Hotels.com

Hotels in Mesa

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Mesa?

1. Wagon Wheel Restaurant Bar and Motel

2. Wine Country Inn Palisade

3. Grand Mesa Lodge

4. Best Western Grande River Inn & Suites

5. Spoke and Vine Motel

6. The Alpine Motel

7. Grand River Hotel

8. Western Slope suites

9. The Homestead

10. Grand Vista Hotel Parachute

11. Maison de Terre

12. Stay Wise Inn Cedaredge

13. Quality Inn Grand Junction near University

14. Ramada by Wyndham Grand Junction

15. La Quinta Inn & Suites by Wyndham Grand Junction

16. Comfort Inn Grand Junction I-70

17. Super 8 by Wyndham Grand Junction Colorado

18. Holiday Inn & Suites Grand Junction-Airport by IHG

19. Grand Vista Hotel

20. Clarion Inn Grand Junction

Go beyond your typical stay in Mesa

Price trends for hotels in Mesa

Typical weather for Mesa

Top landmarks in Mesa

Powderhorn Resort

Learn more about Mesa

Check out reviews of Mesa hotels guests love

Super 8 by Wyndham Grand Junction Colorado

Ramada by Wyndham Grand Junction

Grand Vista Hotel

Grand Vista Hotel Parachute

Quality Inn Grand Junction near University

Wagon Wheel Restaurant Bar and Motel

Powderhorn Lodging

Frequently asked questions

Keep exploring