Hotels in Jackson

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A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

A hotel room with two beds, a brick wall, and a wooden headboard.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

1. Drury Inn & Suites Jackson MO

Jackson

$82

$87 total

includes taxes & fees

Nov 1 - Nov 2

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

A hotel room with two beds, a nightstand, a lamp, and a chair.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

2. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

$81

$87 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

3. Comfort Suites Jackson-Cape Girardeau

Jackson

$76

$82 total

includes taxes & fees

Oct 25 - Oct 26

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

4. Town House Inn

Jackson

$71

$77 total

includes taxes & fees

Oct 5 - Oct 6

A modern retail area with a display of local items and snacks.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

5. Tru By Hilton Cape Girardeau

Cape Girardeau

$89

$102 total

includes taxes & fees

Oct 8 - Oct 9

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

6. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

$100

$113 total

includes taxes & fees

Oct 5 - Oct 6

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

7. Drury Inn & Suites Cape Girardeau

Cape Girardeau

$91

$103 total

includes taxes & fees

Oct 14 - Oct 15

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

8. Pear Tree Inn Cape Girardeau West

Cape Girardeau

$72

$81 total

includes taxes & fees

Oct 11 - Oct 12

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

9. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

$101

$114 total

includes taxes & fees

Oct 8 - Oct 9

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

10. Quality Inn Cape Girardeau North

Cape Girardeau

$59

$67 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

A hotel room with a bed, desk, chair, TV, and a small kitchenette area.

11. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

$101

$115 total

includes taxes & fees

Oct 4 - Oct 5

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A hotel room with two beds, a desk, a chair, and a view of the city.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

12. The Riverview

Cape Girardeau

$114

$129 total

includes taxes & fees

Oct 5 - Oct 6

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

An outdoor patio with stone walls, wicker furniture, and large windows.

A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

13. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

$106

$119 total

includes taxes & fees

Oct 8 - Oct 9

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A lobby with seating areas, a reception desk, and a bar.

A spacious living room with a sofa set, a coffee table, and a dining area.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

14. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

$125

$142 total

includes taxes & fees

Oct 12 - Oct 13

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

A hotel room with a bed, a TV, a desk, and a chair.

15. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

$85

$101 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.

A motel with multiple floors, a parking lot, and a staircase leading to the upper floors.

A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

16. Town House Inn Cape Giradreau

Cape Girardeau

$70

$82 total

includes taxes & fees

Oct 2 - Oct 3

A living room with a blue wall, a fireplace, a sofa, and a chair.

A brick building with a sign reading "Mercantile & Hotel".

A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.

A bar area with stools and a counter where a bartender is serving drinks.

17. EC Reed's Mercantile and Hotel

Marble Hill

$117

$127 total

includes taxes & fees

Oct 4 - Oct 5

A rustic cabin-style lodging with a covered porch, picnic tables, and a fire pit.

A lakeside RV resort with wooden cabins, a picnic area, and a reflection in the water.

A swimming pool with a small water slide, surrounded by lounge chairs and umbrellas.

A cabin interior with a kitchenette, a ceiling fan, a television, a sofa, and a window with blinds.

18. Perryville RV Resort

Perryville

$66

$76 total

includes taxes & fees

Oct 6 - Oct 7

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

A fireplace with a decorative mantel, a framed sign, and a small table with plants.

A building with a sign that reads "The Atrium Boutique Hotel".

A bedroom with a brick wall, a bed with patterned bedding, and a shelf with decorative items.

19. The Atrium - A Boutique Hotel

Perryville

$84

$170 total

includes taxes & fees

Oct 2 - Oct 3

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

A hotel room with a kitchenette, a large mirror, a sofa, and a patterned carpet.

A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

20. Super 8 by Wyndham Perryville

Perryville

$70

$80 total

includes taxes & fees

Oct 11 - Oct 12

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Go beyond your typical stay in Jackson

Pet friendly

Pool

Family friendly

Our prices for hotels in Jackson are cheapest in December

Top landmarks in Jackson

Litz Park

8.6/10 (14 reviews)

Litz Park is worth a visit, located 0.8 mi (1.3 km) from central Jackson.

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Lake Boutin

Lake Boutin is 11 mi (17.6 km) from central Jackson, why not stop by during your stay.

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Indian Creek Wild Area

Indian Creek Wild Area is 11.2 mi (18 km) from central Jackson, why not stop by during your stay.

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Vancill Hollow Natural Area

Vancill Hollow Natural Area is 11.6 mi (18.7 km) from central Jackson, why not stop by during your stay.

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Learn more about Jackson

Jackson is well-known for its attractions such as Trail of Tears State Park and Mississippi River. This family-friendly city has something for everyone including restaurants as well as sights like Lake Boutin and Indian Creek Wild Area. All are within a rural setting.

See all hotels in Jackson

A historic building with a dome and columns, surrounded by trees and a paved walkway.

Check out reviews of Jackson hotels guests love

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"No complaints"

Drury Inn & Suites Jackson MO

10/10 Excellent

"One of the best hotels I have stayed in."

Quality Inn Cape Girardeau North

10/10 Excellent

"Great place great breakfast great room staff was great"

Candlewood Suites Cape Girardeau by IHG

10/10 Excellent

"trodo estubo excelente gracias por sus servicios"

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Clean rooms. Nice breakfast. Very nice staff."

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"Upgraded to a 2 room suite. Rey nice room lots of storage. Would definitely stay here again."

Holiday Inn Express & Suites Perryville by IHG

10/10 Excellent

"Check in and check out for 25 rooms was a breeze. Hotel room cards were ready as soon as we approached the hotel counter."

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"Very nice! Bed was comfortable and room had a very large bathroom and shower. Towels were thick and fluffy. Enjoyed having a bar downstairs with a fun friendly staff. Will stay there again when I’m coming through."

Frequently asked questions

What accommodations do travelers like in Jackson?

Guests like La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Drury Inn & Suites Jackson MO and Comfort Suites Jackson-Cape Girardeau.

Can I book a refundable hotel in Jackson?

If you need the flexibility to change your travel plans to Jackson, most properties offer refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where should I consider staying in Jackson if I'm looking for a budget-friendly accommodation?

Comfort Suites Jackson-Cape Girardeau is an accommodation you might want to consider that'll save you money.

Where can I stay in Jackson if I want a vacation home instead of a hotel?

Browse 5 vacation homes on our site.

What will the weather in Jackson be like during my visit?

July and August are typically the warmest months in Jackson when the average temp is 76°F. January and February are the coldest months when the average temperature is 40°F. April and March are the months with the most rain.

Why should I book my Jackson hotel through Hotels.com?

There are lots of reasons to book your Jackson trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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Hotels in Jackson

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Jackson?

1. Drury Inn & Suites Jackson MO

2. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3. Comfort Suites Jackson-Cape Girardeau

4. Town House Inn

5. Tru By Hilton Cape Girardeau

6. Drury Plaza Hotel Cape Girardeau Conference Center

7. Drury Inn & Suites Cape Girardeau

8. Pear Tree Inn Cape Girardeau West

9. Fairfield Inn & Suites by Marriott Cape Girardeau

10. Quality Inn Cape Girardeau North

11. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

12. The Riverview

13. Hampton Inn Cape Girardeau I 55 East

14. Courtyard by Marriott Cape Girardeau Downtown

15. Candlewood Suites Cape Girardeau by IHG

16. Town House Inn Cape Giradreau

17. EC Reed's Mercantile and Hotel

18. Perryville RV Resort

19. The Atrium - A Boutique Hotel

20. Super 8 by Wyndham Perryville

Go beyond your typical stay in Jackson

Price trends for hotels in Jackson

Typical weather for Jackson

Top landmarks in Jackson

Litz Park

Lake Boutin

Indian Creek Wild Area

Vancill Hollow Natural Area

Learn more about Jackson

Check out reviews of Jackson hotels guests love

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Jackson MO

Quality Inn Cape Girardeau North

Candlewood Suites Cape Girardeau by IHG

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Inn & Suites Cape Girardeau

Holiday Inn Express & Suites Perryville by IHG

Courtyard by Marriott Cape Girardeau Downtown

Frequently asked questions

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