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Hotels in South San Francisco

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DoubleTree by Hilton San Francisco South Airport Blvd
DoubleTree by Hilton San Francisco South Airport Blvd
4.0 star property
South San Francisco
8.4 out of 10, Very Good, (2,113 reviews)
Escape the busy travel hustle in this serene hotel just 7 minutes from SFO. Free airport shuttle, comfortable beds, and helpful staff create a peaceful retreat. Unwind at the bar or maintain your routine in the fitness center after exploring nearby attractions.
The price is $103
$122 total
includes taxes & fees
Feb 20 - Feb 21
DoubleTree by Hilton San Francisco South Airport Blvd
Sonesta Select San Francisco Airport Oyster Point Waterfront
Sonesta Select San Francisco Airport Oyster Point Waterfront
3.0 star property
Oyster Point
8.6 out of 10, Excellent, (1,968 reviews)
Wake up to stunning San Francisco Bay views at this South San Francisco hotel offering a free airport shuttle and American cuisine at The Commons. Just 9 minutes from SFO with easy access to Moscone Convention Center, guests praise the spotless rooms and attentive staff.
The price is $106
$126 total
includes taxes & fees
Feb 13 - Feb 14
Sonesta Select San Francisco Airport Oyster Point Waterfront
Travelodge by Wyndham San Francisco Airport North
Travelodge by Wyndham San Francisco Airport North
2.0 star property
South San Francisco
5.8 out of 10, (3,149 reviews)
Splash in the outdoor pool or grab a bite at the on-site restaurant. Free WiFi and airport shuttle make travel seamless. Just a short drive from Oracle Park, Chase Center, and San Francisco Bay, with SFO Museum nearby.
The price is $51
$61 total
includes taxes & fees
Feb 10 - Feb 11
Travelodge by Wyndham San Francisco Airport North
Hilton Garden Inn San Francisco Arpt North
Hilton Garden Inn San Francisco Arpt North
3.0 star property
The East Side
8.6 out of 10, Excellent, (1,000 reviews)
Step into tranquility at this South San Francisco hotel, just a 13-minute walk from the station. The convenient location puts you close to shops, restaurants, and major attractions. Rooms include microwaves and refrigerators, while a fitness center and restaurant keep you energized.
The price is $92
$108 total
includes taxes & fees
Feb 15 - Feb 16
Hilton Garden Inn San Francisco Arpt North
La Quinta Inn & Suites by Wyndham San Francisco Airport N
La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.0 out of 10, Very Good, (2,020 reviews)
Just 5 minutes from SFO, this hotel offers a peaceful retreat with an outdoor pool and 24-hour fitness center. Enjoy complimentary breakfast before exploring nearby attractions or catching the free airport shuttle. Walking distance to South San Francisco Station.
The price is $101
$119 total
includes taxes & fees
Feb 13 - Feb 14
La Quinta Inn & Suites by Wyndham San Francisco Airport N
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
4.0 star property
Oyster Point
9.2 out of 10, Wonderful, (1,000 reviews)
Experience waterfront tranquility at this South San Francisco hotel with convenient access to SFO. The indoor pool and 24-hour fitness center offer relaxation, while AC Waterfront Lounge serves local cuisine. Just a short drive from San Francisco Bay and Moscone Convention Center.
The price is $125
$149 total
includes taxes & fees
Feb 21 - Feb 22
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
2.5 star property
The East Side
9.0 out of 10, Wonderful, (454 reviews)
Newly renovated hotel with complimentary breakfast sits just 4 miles from SFO Airport, offering scheduled shuttle service. Close to Chase Center and San Francisco Bay, this contemporary space features clean rooms, a fitness center, and friendly, attentive staff.
The price is $121
$142 total
includes taxes & fees
Feb 14 - Feb 15
Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
Hampton Inn San Francisco Airport
Hampton Inn San Francisco Airport
2.5 star property
The East Side
8.6 out of 10, Excellent, (1,003 reviews)
The price is $95
$114 total
includes taxes & fees
Mar 8 - Mar 9
Hampton Inn San Francisco Airport
Best Western Plus Grosvenor Airport Hotel
Best Western Plus Grosvenor Airport Hotel
3.0 star property
South San Francisco
8.4 out of 10, Very Good, (1,732 reviews)
This business-friendly hotel offers convenient perks including free breakfast and a fitness center just minutes from SFO airport. Visit San Francisco Bay or Chase Center with easy access, and return to clean rooms with attentive staff always ready to assist travelers.
The price is $109
$128 total
includes taxes & fees
Feb 20 - Feb 21
Best Western Plus Grosvenor Airport Hotel
Hotel Focus SFO
Hotel Focus SFO
3.0 star property
The East Side
7.6 out of 10, Good, (1,528 reviews)
Free airport shuttle makes travel stress-free at this South San Francisco hotel. Enjoy complimentary WiFi and on-the-go breakfast daily. Within walking distance of South San Francisco Station and a short drive to SFO Museum.
The price is $89
$105 total
includes taxes & fees
Feb 19 - Feb 20
Hotel Focus SFO
Embassy Suites by Hilton San Francisco Airport Oyster Point
Embassy Suites by Hilton San Francisco Airport Oyster Point
3.5 star property
The East Side
8.6 out of 10, Excellent, (1,285 reviews)
Just minutes from San Francisco International Airport with shuttle service and walking distance to South San Francisco Station. Enjoy the indoor pool, 24-hour fitness center, and restaurant with bar after a busy day. Fellow travelers praise the helpful staff.
The price is $138
$162 total
includes taxes & fees
Feb 15 - Feb 16
Embassy Suites by Hilton San Francisco Airport Oyster Point
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
3.0 star property
Oyster Point
8.4 out of 10, Very Good, (1,010 reviews)
Steps from San Francisco Bay, this hotel offers a refreshing outdoor pool and hot tub. Each room includes handy microwaves and refrigerators. A free airport shuttle, fitness center, and complimentary breakfast make exploring nearby attractions effortless.
The price is $119
$141 total
includes taxes & fees
Mar 5 - Mar 6
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
Home2 Suites by Hilton San Francisco Airport North
Home2 Suites by Hilton San Francisco Airport North
3.0 star property
The East Side
8.8 out of 10, Excellent, (1,183 reviews)
Just minutes from SFO Airport with complimentary shuttle service, this hotel offers free daily buffet breakfast and WiFi. Walk to South San Francisco Station for city access, or drive to Oracle Park and Chase Center within 15 minutes.
The price is $115
$134 total
includes taxes & fees
Feb 20 - Feb 21
Home2 Suites by Hilton San Francisco Airport North
Hotel Nova SFO
Hotel Nova SFO
2.5 star property
South San Francisco
8.6 out of 10, Excellent, (1,003 reviews)
The price is $115
$134 total
includes taxes & fees
Feb 20 - Feb 21
Hotel Nova SFO
Four Points by Sheraton Hotel & Suites San Francisco Airport
Four Points by Sheraton Hotel & Suites San Francisco Airport
3.0 star property
South San Francisco
7.8 out of 10, Good, (1,000 reviews)
Relax in this South San Francisco hotel where free WiFi keeps you connected while the fitness center helps maintain your workout routine. Just a 15-minute drive from Moscone Convention Center and within walking distance of South San Francisco Station.
The price is $97
$114 total
includes taxes & fees
Mar 1 - Mar 2
Four Points by Sheraton Hotel & Suites San Francisco Airport
Rodeway Inn South San Francisco Airport
Rodeway Inn South San Francisco Airport
2.0 star property
South San Francisco
7.0 out of 10, Good, (1,001 reviews)
Modern accommodations near San Francisco Intl Airport with free WiFi and parking. Just 7 minutes from SFO Museum and within walking distance of South San Francisco Station. Travelers appreciate the helpful 24-hour staff and secure surroundings.
The price is $75
$89 total
includes taxes & fees
Feb 15 - Feb 16
Rodeway Inn South San Francisco Airport
Holiday Inn Express San Francisco-Airport North by IHG
Holiday Inn Express San Francisco-Airport North by IHG
2.5 star property
South San Francisco
8.2 out of 10, Very Good, (1,010 reviews)
Wake up to a free buffet breakfast at this South San Francisco hotel with complimentary airport shuttles just minutes from SFO. Rooms include refrigerators and microwaves, while a fitness center and hot tub help you unwind after exploring nearby attractions.
The price is $107
$126 total
includes taxes & fees
Feb 20 - Feb 21
Holiday Inn Express San Francisco-Airport North by IHG
Airport Inn
Airport Inn
2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (984 reviews)
Minutes from San Francisco International Airport with a 14-minute walk to South San Francisco Station. Enjoy free WiFi and parking at this convenient motel. Guests appreciate the helpful staff while SFO Museum and Cow Palace attractions are nearby.
The price is $110
$129 total
includes taxes & fees
Feb 9 - Feb 10
Airport Inn
Larkspur Landing Extended Stay Suites South San Francisco
Larkspur Landing Extended Stay Suites South San Francisco
3.0 star property
The East Side
7.8 out of 10, Good, (1,000 reviews)
This tranquil hotel offers free self-serve breakfast and WiFi, with comfortable suites just 14 minutes' walk from South San Francisco Station. Oracle Park and Moscone Convention Center are a short drive away, while the fitness center helps maintain your routine.
The price is $119
$140 total
includes taxes & fees
Feb 27 - Feb 28
Larkspur Landing Extended Stay Suites South San Francisco
Inn By The SFO
Inn By The SFO
2.0 star property
Downtown South San Francisco
7.8 out of 10, Good, (1,002 reviews)
This serene hotel sits just minutes from San Francisco International Airport with free WiFi and parking. Walk to South San Francisco Station or drive to downtown attractions. The friendly staff ensures peaceful stays in clean, comfortable rooms.
The price is $89
$105 total
includes taxes & fees
Feb 10 - Feb 11
Inn By The SFO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Check out pet-friendly hotels in South San Francisco

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit South San Francisco?

Our prices for hotels in South San Francisco are cheapest in December
Price trends for hotels in South San Francisco
Pricing is based on two traveler single night rates
View properties in February
Currently viewing crowd sizes and weather for February.
Typical weather for South San Francisco
February
High 15°C / low 9°C. Sunny most days.
View properties in February
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September, no crowd data, average high temperature 20 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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November, no crowd data, average high temperature 17 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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December, no crowd data, average high temperature 14 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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January, no crowd data, average high temperature 14 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
Monthly weather averages (˚C)

Top neighborhoods in South San Francisco

Downtown South San Francisco

Downtown South San Francisco buzzes with a blend of biotech innovation and cultural diversity. Corporate towers and colorful murals tell the story of this unique business hub. You'll find authentic taquerias, dim sum houses, and Filipino eateries nestled between modern office campuses along Grand Avenue. The neighborhood comes alive during weekdays when professionals fill its plazas and restaurants. Getting around is a breeze with nearby BART and Caltrain stations connecting you to San Francisco proper and beyond. Business hotels cater mostly to corporate travelers with practical amenities. The area quiets down after work hours, offering a genuine glimpse into Bay Area life away from tourist crowds.

Oyster Point

Oyster Point balances sleek biotech campuses with stunning San Francisco Bay views. The waterfront promenade offers perfect spots for watching waves crash against the shore or catching a beautiful sunset. Modern plazas feature public art installations while walking paths showcase both cutting-edge architecture and natural bay ecosystems. Business travelers appreciate the corporate hotels with meeting facilities and convenient access to office buildings. Dining options cater primarily to weekday lunch crowds, with most establishments closing early evening. The area is best explored by car, though waterfront paths provide scenic strolling opportunities away from the corporate hustle.

The East Side

The East Side delivers authentic local life away from San Francisco's tourist traps. Catch Bay views from San Bruno Point Park or explore diverse family-owned restaurants along Grand Avenue serving up killer tacos and pho. This residential neighborhood mixes Hispanic and Asian influences that shine through local markets and casual eateries. Budget travelers appreciate the affordable motels and extended-stay options that cost way less than downtown San Francisco. Buses connect to BART and Caltrain, though having wheels helps. Most spots close early, so plan your food adventures accordingly.

Paradise Valley

Paradise Valley offers a peaceful retreat from San Francisco's bustle while keeping you close to the action. This quiet residential neighborhood in South San Francisco balances suburban calm with convenient access to nearby attractions. Take a stroll through San Bruno Point Park or venture to local spots like K1 Speed for some indoor racing fun. Budget-friendly accommodations make Paradise Valley an appealing base for Bay Area exploration. The neighborhood's proximity to San Francisco International Airport and major highways ensures easy connections throughout the region. With ample street parking and minimal crowds, you'll appreciate this low-key alternative to the city's more hectic districts.

Serra Highlands

Serra Highlands offers a peaceful retreat from the Bay Area buzz with its hillside streets and family-friendly vibe. While there aren't tourist attractions within the neighborhood itself, you'll enjoy stunning panoramic views, quiet walking paths, and easy access to nearby highlights like Serramonte Center. Morning fog rolling over the hills creates a mystical atmosphere worth waking up for. Getting around requires a car or rideshare, as public transit is limited in this residential area. Accommodations consist mainly of vacation rental homes with suburban comforts like driveways and yards. For dining and shopping, you'll need to venture to surrounding commercial areas, making Serra Highlands perfect for travelers seeking authentic local living.

Top landmarks in South San Francisco

Learn more about South San Francisco

Look beyond the iconic 'South San Francisco The Industrial City' sign crowning Sign Hill Park for a city with its own distinct identity. Grand Avenue serves up a global feast of family-run eateries where locals debate the merits of each dumpling house. San Bruno Mountain offers hiking trails with sweeping Bay views that explain why residents tolerate the fog. See's Candies factory tours satisfy sweet tooths, while K1 Speed delivers indoor racing thrills. The Convention Center hosts events that draw visitors who are surprised to discover this isn't simply San Francisco's southern neighborhood. Despite tripling in population since World War II, 'South City' maintains its working-class roots while embracing its role as a Peninsula destination in its own right.

#BVSBlue Aristodes Demetries, One Of Americas Best Known Sculptors Created This Steel Sculpture As A Symbol Of Cabot Cabot And Forbes Industrial Park. Situated 243 Feet Above Sea Level It Rises To A Be Seen From The Bay Bridge, The East Bay and SFO. Called The Wind Harp Locally. It emits eerie sounds when the wind 💨is at its strongest.
Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀
Open Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀

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Frequently asked questions

What accommodations do travelers like in South San Francisco?
Can I book refundable accommodations in South San Francisco?
If you need the flexibility to change your travel plans to South San Francisco, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in South San Francisco if I want a vacation rental instead of a hotel?
If you're looking for a good alternative to a hotel, review our selection of 33 vacation homes. In addition, you can choose from 11 apartments.
What will the weather in South San Francisco be like during my visit?
The warmest months in South San Francisco are usually September and August with an average temp of 62°F. February and January are the chilliest months when the average temp is 53°F. The rainiest months are December and January.
Why should I book my South San Francisco accommodation with Hotels.com?
There are lots of reasons to book your South San Francisco trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.