
Hotels in La Mesa
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in La Mesa?




Motel 6 La Mesa, CA - San Diego
Motel 6 La Mesa, CA - San Diego
2.0 star property
La Mesa
7.4 out of 10, Good, (981)
7.4/10
Good
(981)
The price is $90
$90
$99 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Heritage Inn La Mesa
Heritage Inn La Mesa
2.0 star property
La Mesa
7.0 out of 10, Good, (1221)
7.0/10
Good
(1221)
The price is $54
$54
$59 total
includes taxes & fees
Jan 7 - Jan 8, 2026




Best Western Plus La Mesa San Diego
Best Western Plus La Mesa San Diego
2.5 star property
La Mesa
8.4 out of 10, Very Good, (1000)
8.4/10
Very Good
(1000)
The price is $114
$114
$125 total
includes taxes & fees
Jan 18 - Jan 19, 2026




Holiday Inn Express La Mesa Near SDSU by IHG
Holiday Inn Express La Mesa Near SDSU by IHG
3.0 star property
La Mesa
8.2 out of 10, Very Good, (459)
8.2/10
Very Good
(459)
The price is $191
$191
$210 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Motel 6 La Mesa, CA
Motel 6 La Mesa, CA
2.0 star property
La Mesa
7.2 out of 10, Good, (1001)
7.2/10
Good
(1001)
The price is $100
$100
$110 total
includes taxes & fees
Jan 11 - Jan 12, 2026




Lamplighter Inn & Suites at SDSU
Lamplighter Inn & Suites at SDSU
2.5 star property
Mid-City
9.0 out of 10, Wonderful, (1338)
9.0/10
Wonderful
(1338)
The price is $129
$129
$146 total
includes taxes & fees
Jan 1 - Jan 2, 2026




DoubleTree by Hilton Hotel San Diego - Mission Valley
DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
Mission Valley
8.4 out of 10, Very Good, (1442)
8.4/10
Very Good
(1442)
The price is $112
$112
$129 total
includes taxes & fees
Jan 3 - Jan 4, 2026




Staypineapple, Hotel Z, Gaslamp San Diego
Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1001)
9.4/10
Exceptional
(1001)
The price is $99
$99
$144 total
includes taxes & fees
Jan 6 - Jan 7, 2026




Legacy Resort Hotel & Spa
Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2949)
9.2/10
Wonderful
(2949)
The price is $152
$152
$175 total
includes taxes & fees
Jan 5 - Jan 6, 2026




The DEXTRO Little Italy, BW Premier Collection
The DEXTRO Little Italy, BW Premier Collection
3.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (834)
8.8/10
Excellent
(834)
The price is $126
$126
$146 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Days Inn by Wyndham San Diego Hotel Circle
Days Inn by Wyndham San Diego Hotel Circle
3.0 star property
Mission Valley
8.0 out of 10, Very Good, (2425)
8.0/10
Very Good
(2425)
The price is $84
$84
$97 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Margaritaville Hotel San Diego Gaslamp Quarter
Margaritaville Hotel San Diego Gaslamp Quarter
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1178)
9.0/10
Wonderful
(1178)
The price is $139
$139
$202 total
includes taxes & fees
Jan 2 - Jan 3, 2026




Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1239)
9.0/10
Wonderful
(1239)
The price is $146
$146
$170 total
includes taxes & fees
Jan 3 - Jan 4, 2026




The Atwood Hotel San Diego - SeaWorld/Zoo
The Atwood Hotel San Diego - SeaWorld/Zoo
3.0 star property
Mission Valley
8.0 out of 10, Very Good, (1839)
8.0/10
Very Good
(1839)
The price is $83
$83
$96 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Kings Inn San Diego
Kings Inn San Diego
2.5 star property
Mission Valley
8.8 out of 10, Excellent, (3581)
8.8/10
Excellent
(3581)
The price is $76
$76
$88 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Handlery Hotel
Handlery Hotel
3.5 star property
Mission Valley
8.2 out of 10, Very Good, (2262)
8.2/10
Very Good
(2262)
The price is $86
$86
$111 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Homewood Suites by Hilton San Diego Mission Valley/Zoo
Homewood Suites by Hilton San Diego Mission Valley/Zoo
3.0 star property
Mission Valley
8.4 out of 10, Very Good, (1001)
8.4/10
Very Good
(1001)
The price is $127
$127
$146 total
includes taxes & fees
Jan 7 - Jan 8, 2026




Courtyard by Marriott San Diego Downtown Little Italy
Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (165)
8.8/10
Excellent
(165)
The price is $122
$122
$141 total
includes taxes & fees
Jan 7 - Jan 8, 2026




Hard Rock Hotel San Diego
Hard Rock Hotel San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (3179)
9.0/10
Wonderful
(3179)
The price is $170
$170
$243 total
includes taxes & fees
Jan 1 - Jan 2, 2026




Holiday Inn Express & Suites San Diego - Mission Valley by IHG
Holiday Inn Express & Suites San Diego - Mission Valley by IHG
2.5 star property
Mission Valley
8.8 out of 10, Excellent, (1001)
8.8/10
Excellent
(1001)
The price is $108
$108
$127 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in La Mesa
Apart hotel
Ocean view
Apartment
Pet friendly
Resort
Cottage
Family friendly
Condo
trending_down When is the best time to visit La Mesa?
When is the best time to visit La Mesa?Our prices for hotels in La Mesa are cheapest in December
When is the best time to visit La Mesa?
When is the best time to visit La Mesa?
Our prices for hotels in La Mesa are cheapest in December
Price trends for hotels in La Mesa
Pricing is based on two traveler single night rates
Currently viewing crowd sizes and weather for December.trending_up High crowds
Typical weather for La Mesa
December
High 18°C / low 10°C. Sunny most days.
View properties in December 18°
December, High crowds, average high temperature 18 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
19°
January, Low crowds, average high temperature 19 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
19°
February, Low crowds, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
20°
March, Low crowds, average high temperature 20 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
21°
April, Low crowds, average high temperature 21 degrees Celsius, average low temperature 12 degrees Celsius. Sunny most days.
12°
22°
May, Moderate crowds, average high temperature 22 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
25°
June, Moderate crowds, average high temperature 25 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
16°
28°
July, High crowds, average high temperature 28 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
19°
29°
August, High crowds, average high temperature 29 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
28°
September, Moderate crowds, average high temperature 28 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
19°
26°
October, High crowds, average high temperature 26 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
16°
22°
November, Moderate crowds, average high temperature 22 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
Monthly weather averages (˚C)
Top neighborhoods in La Mesa
Mount Helix
La Mesa's Mount Helix neighborhood offers attractions including Mount Helix Park.
Top landmarks in La Mesa
Computer Museum of America
3.5/5 (12 reviews)
Computer Museum of America is 1 mi (1.6 km) from central La Mesa, why not stop by during your stay. Hotels.com travelers also say the area is walkable and has lots of nice beaches. If you want to experience more of the culture La Mesa has to offer, head to San Diego State University, Cal Coast Credit Union Open Air Theater, and Viejas Arena.
Learn more about La Mesa
Between the bustle of San Diego and the quiet of the hills, La Mesa lives up to its 'Jewel of the Hills' nickname without trying too hard. The historic Village area offers boutiques and cafés where locals actually eat, not just places that survive on tourist traffic. Mount Helix rewards a short climb with panoramic views that explain why everyone in California seems suspiciously content. Lake Murray Park provides a refreshing escape where fishing lines dangle alongside kayakers who've discovered this urban oasis. Train enthusiasts find unexpected delight at the Pacific Southwest Railway Museum, where vintage locomotives sit frozen in time.

Check out reviews of La Mesa hotels guests love

Wyndham San Diego Bayside
10/10 Excellent
"Room was clean, staff was friendly, Breakfast at Claim Jumper’s is very good as is Hazelwood’s"

San Diego Marriott La Jolla
10/10 Excellent
"Clean, comfortable rooms. Luxurious bedding. Great area! "

Sheraton San Diego Resort
10/10 Excellent
"Staff very friendly and responsive - especially the housekeepers. Elevators quick and always at the ready."

Hard Rock Hotel San Diego
10/10 Excellent
"Good food"

The DEXTRO Little Italy, BW Premier Collection
10/10 Excellent
"All was excellent thank you very much "

Legacy Resort Hotel & Spa
10/10 Excellent
"Excellent stay. Juanita was very helpful. Staff was amazing."

DoubleTree by Hilton Hotel San Diego - Mission Valley
10/10 Excellent
"Don't know about the bar, did not eat breakfast"

The Dana on Mission Bay
10/10 Excellent
"Great spot, great hotel, great food options!"

Hilton San Diego Mission Valley
10/10 Excellent
"Loved the easy check in process via the app! "
Frequently asked questions
What accommodations do travelers like in La Mesa?
Best Western Plus La Mesa San Diego, Holiday Inn Express La Mesa Near SDSU by IHG and Motel 6 La Mesa, CA are all properties that our guests really like.
Can I book a refundable accommodation in La Mesa?
If you need the flexibility to change your travel plans to La Mesa, most hotels offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in La Mesa if I want a vacation home instead of a hotel?
If you're looking for a good alternative to a hotel, review our selection of 60 vacation homes. In addition, you can choose from 9 apartments.
What will the weather in La Mesa be like during my trip?
August and September are typically the warmest months in La Mesa when the average temp is 72°F. February and January are the coldest months when the average temperature is 56°F. December and February are the months with the most rain.
Why should I book my La Mesa hotel through Hotels.com?
There are lots of reasons to book your La Mesa trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.