Hotels in Santa Cruz
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Aug 8 - Aug 9Tomorrow
Aug 9 - Aug 10Next weekend
Aug 14 - Aug 16In two weeks
Aug 21 - Aug 23Top 5 hotels in Santa Cruz at a glance
- Ibis Santa Cruz DE LA Sierra — 3-star hotel in Santa Cruz. Guest rating: 9.4/10 — Exceptional.
- Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel — 3.5-star hotel in Santa Cruz. Guest rating: 9.0/10 — Wonderful.
- Marriott Santa Cruz de la Sierra Hotel — 5-star hotel in Santa Cruz. Guest rating: 9.0/10 — Wonderful.
- Camino Real Hotel — 4.5-star hotel in Santa Cruz. Guest rating: 9.0/10 — Wonderful.
- Premium Suites Deluxe Aparthotel Equipetrol — 3.5-star hotel in Santa Cruz. Guest rating: 9.0/10 — Wonderful.
Where to stay in Santa Cruz?
Ibis Santa Cruz DE LA Sierra
Ibis Santa Cruz DE LA SierraSanta Cruz
$34
$34 total
Aug 23 - Aug 24
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio HotelSanta Cruz
$127
$127 total
Aug 16 - Aug 17
Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra HotelSanta Cruz
$106
$106 total
Aug 14 - Aug 15
Premium Suites Deluxe Aparthotel Equipetrol
Premium Suites Deluxe Aparthotel EquipetrolSanta Cruz
$35
$40 total
Aug 20 - Aug 21
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Hampton by Hilton Santa Cruz/Equipetrol, BoliviaSanta Cruz
$74
$74 total
Aug 15 - Aug 16
Delfines Collection Hotel By Mercure
Delfines Collection Hotel By MercureSanta Cruz
$48
$48 total
Aug 23 - Aug 24
TRYP by Wyndham Santa Cruz
TRYP by Wyndham Santa CruzSanta Cruz
$98
$98 total
Aug 9 - Aug 10
Novotel Santa Cruz De La Sierra
Novotel Santa Cruz De La SierraSanta Cruz
$124
$124 total
Sep 1 - Sep 2
Alfonsina Hotel Boutique by Inboccaluppo
Alfonsina Hotel Boutique by InboccaluppoSanta Cruz
$108
$108 total
Aug 12 - Aug 13
Swissôtel Santa Cruz De La Sierra
Swissôtel Santa Cruz De La SierraSanta Cruz
$148
$148 total
Aug 23 - Aug 24
Cosmopolitano Hotel Boutique
Cosmopolitano Hotel BoutiqueSanta Cruz
$59
$59 total
Aug 22 - Aug 23
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$50 off
Ibis Santa Cruz DE LA Sierra$61
per night
$121 total
$171
per night
$342 total
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$33 off
TRYP by Wyndham Santa Cruz$93
per night
$185 total
$132 off
Alfonsina Hotel Boutique by Inboccaluppo$109
per night
$218 total
$56 off
Hotel LP Santa Cruz Centro$44
per night
$93 total
$6 off
Apart Hotel Premium Suites Santa Cruz$27
per night
$54 total
$69
per night
$138 total
Sign in for extra savings
$36
per night
$36 total
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$162
per night
$162 total
Sign in for extra savings
$28 off
Cosmopolitano Hotel Boutique$91
per night
$91 total
$131
per night
$131 total
Sign in for extra savings
$11 off
TRYP by Wyndham Santa Cruz$98
per night
$98 total
$15 off
Alfonsina Hotel Boutique by Inboccaluppo$134
per night
$134 total
$3 off
Apart Hotel Premium Suites Santa Cruz$27
per night
$27 total
$24 off
Hotel LP Santa Cruz Centro$52
per night
$57 total
Check out hotels with a spa in Santa Cruz
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio HotelSanta Cruz
$127
$127 total
Aug 16 - Aug 17
$148
$148 total
Aug 23 - Aug 24
$106
$106 total
Aug 14 - Aug 15
$77
$77 total
Aug 10 - Aug 11
You may also like hotels with pools in Santa Cruz
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio HotelSanta Cruz
$127
$127 total
Aug 16 - Aug 17
$35
$40 total
Aug 20 - Aug 21
$106
$106 total
Aug 14 - Aug 15
$59
$59 total
Aug 22 - Aug 23
$48
$48 total
Aug 23 - Aug 24
$124
$124 total
Sep 1 - Sep 2
You can also stay at family-friendly hotels in Santa Cruz
$34
$34 total
Aug 23 - Aug 24
$106
$106 total
Aug 14 - Aug 15
$27
$27 total
Aug 9 - Aug 10
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio HotelSanta Cruz
$127
$127 total
Aug 16 - Aug 17
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Hampton by Hilton Santa Cruz/Equipetrol, BoliviaSanta Cruz
$74
$74 total
Aug 15 - Aug 16
$124
$124 total
Sep 1 - Sep 2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all propertiesGo beyond your typical stay in Santa Cruz
Family friendly
Pet friendly
Our prices for hotels in Santa Cruz are cheapest in February
Our prices for hotels in Santa Cruz are cheapest in February
Price trends for hotels in Santa Cruz
Pricing is based on two traveler single night rates
Top neighborhoods in Santa Cruz
Top landmarks in Santa Cruz
Plaza 24 de Septiembre
8.8/10 (164 reviews)
If you're planning a bit of sightseeing during your trip, head to Plaza 24 de Septiembre— just one of the monuments in central Santa Cruz.
San Lorenzo Cathedral
9.0/10 (84 reviews)
San Lorenzo Cathedral is in the heart of Santa Cruz, so why not stop by during your stay.
Ventura Mall
9.0/10 (183 reviews)
If you like shopping, take time out to go to Ventura Mall when in Santa Cruz.
Guembe Biocenter
8.8/10 (60 reviews)
Ready for an education in local botany? Guembe Biocenter should make your list of places to visit, located 1.2 mi (2 km) from central Colinas del Urubo. Want to stretch your legs some more? Head to Arenal Park, located nearby.
Santa Cruz Zoo
8.4/10 (53 reviews)
It's feeding time at the zoo! If you want to be reminded of some of the great animals our world is home to, you might want to pay a trip to Santa Cruz Zoo, located 1.7 mi (2.8 km) from central Santa Cruz. If you have fun at Santa Cruz Zoo, you'll love Guembe Biocenter and Artecampo, both located nearby.
Cine Center
8.0/10 (53 reviews)
Cine Center is 1 mi (1.6 km) from central Santa Cruz, why not stop by during your stay. If you enjoy the show and want to see another, Casa Municipal de Cultura Raúl Otero Reiche isn't far.
Ramon Tahuichi Aguilera Stadium
8.4/10 (18 reviews)
You can catch an event at Ramon Tahuichi Aguilera Stadium, located 0.8 mi (1.3 km) from central Santa Cruz.
Lomas de Arena Regional Park
8.4/10 (28 reviews)
Commune with nature and explore Lomas de Arena Regional Park located 10.7 mi (17.1 km) from central Santa Cruz.
Learn more about Santa Cruz
Santa Cruz is applauded for its cultural attractions such as Cine Center and Ethno-folkloric Museum.
See all hotels in Santa Cruz
Check out reviews of Santa Cruz hotels guests love
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
10/10 Excellent
"Como siempre el Mejor nivel para estancias en Santa Cruz"
Sun Hotel
10/10 Excellent
"El mejor servicio cerca del aeropuerto de Viru Viru"
Marriott Santa Cruz de la Sierra Hotel
10/10 Excellent
"Everything was great. Came for a business trip and would stay here again."
Premium Suites Deluxe Aparthotel Equipetrol
10/10 Excellent
"great place to stay!"
Camino Real Hotel
10/10 Excellent
"Enjoyed our stay. Warm welcome from the staff and great service. Highly recommended"
Ibis Santa Cruz DE LA Sierra
10/10 Excellent
"Great deal"
Hotel Cortez
10/10 Excellent
"Very good."
Hotel LP Equipetrol
8/10 Good
"El cuarto agradable, pero faltó servicio de ayuda para subir y bajar maletas, también servicio adecuado de taxi para moverse en Santa Cruz"
Alfonsina Hotel Boutique by Inboccaluppo
10/10 Excellent
"Good hotel. Very contemporary; buffet breakfast included. We walked to the old part of the city/cathedral - probably about 40 minutes walk but can stop for a coffee along the way! Restaurant and bar in hotel. Hotel also close to many other restaurants/bars"