Hotels in Santa Cruz

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Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (376 reviews)
A sophisticated retreat in Santa Cruz featuring spa services with massages and facials. Two restaurants serving international cuisine complement the fitness center and hot tub. Near Patio Design LifeStyle Center and Ventura Mall with convenient airport access.
The price is $127
$127 total
May 29 - May 30
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (114 reviews)
Discover Santa Cruz from this modern hotel with a bar, café, and business-friendly amenities. Located near Municipal Library and Patio Design LifeStyle Center, enjoy free WiFi and parking while the helpful staff ensures a pleasant stay.
The price is $59
$59 total
May 22 - May 23
Ibis Santa Cruz DE LA Sierra

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (426 reviews)
Set in a prime Santa Cruz location, this luxurious hotel features indoor and outdoor pools, 2 bars, and a full-service spa offering massages. La Tranquera restaurant serves daily meals, with Ventura Mall and Santa Cruz Zoo nearby for exploration.
The price is $135
$135 total
May 28 - May 29
Camino Real Hotel

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (272 reviews)
Upscale retreat with a Roof Top Bar & Lounge serving three daily meals and stunning city views. Free breakfast, WiFi and parking complement the fitness center. Ventura Mall and Patio Design LifeStyle Center wait just minutes away.
The price is $94
$94 total
May 24 - May 25
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (233 reviews)
Set in Santa Cruz with international dining at Toborochi restaurant, this luxury hotel offers relaxing massages at the spa. Cool off in the outdoor pool, work out in the fitness center, or enjoy a drink at the bar after exploring nearby Ventura Mall.
The price is $111
$111 total
May 29 - May 30
Marriott Santa Cruz de la Sierra Hotel

Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro
3.0 star property
Santa Cruz
8.0 out of 10, Very Good, (285 reviews)
Located in the heart of Santa Cruz, this hotel offers convenient access to Ramon Tahuichi Aguilera Stadium and Blacutt Square. Enjoy a meal at the restaurant or relax with a drink at the bar after exploring. Free WiFi and parking enhance your stay.
The price is $42
$47 total
May 20 - May 21
Hotel LP Santa Cruz Centro

Hotel LP Equipetrol

Hotel LP Equipetrol
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (206 reviews)
Immerse yourself in Santa Cruz's vibrant energy at this modern hotel. Just minutes from Ventura Mall and Santa Cruz Zoo, enjoy convenient amenities including a pool, room service, and free WiFi for a seamless stay.
The price is $39
$44 total
May 22 - May 23
Hotel LP Equipetrol

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (161 reviews)
Immerse in Santa Cruz's vibrant scene at this Art Deco haven with a refreshing outdoor pool and relaxing sauna. Just minutes from Patio Design LifeStyle Center and the Zoo, enjoy complimentary breakfast, WiFi, and parking after a day of exploration.
The price is $99
$99 total
May 19 - May 20
TRYP by Wyndham Santa Cruz

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (138 reviews)
The price is $107
$107 total
May 30 - May 31
Hotel Cortez

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (100 reviews)
The price is $39
$39 total
May 24 - May 25
Premium Suites Deluxe Aparthotel Equipetrol

Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (107 reviews)
Central Santa Cruz location with free WiFi and parking, close to Las Brisas Shopping Center and the Zoo. This hotel provides a convenient base for exploring the area, with the airport just 24 minutes away and railway station nearby.
The price is $36
$36 total
Jun 16 - Jun 17
Hotel G

Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (131 reviews)
Slip into vacation mode at this boutique retreat with an outdoor pool and poolside bar. Near Sacred Art Museum and Franco Aleman Cultural Center, the hotel offers free breakfast, WiFi, and parking. Massages add extra bliss after exploring the area.
The price is $79
$79 total
Jun 12 - Jun 13
Cosmopolitano Hotel Boutique

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (49 reviews)
Immerse in serenity at this welcoming retreat featuring a full-service spa, outdoor pool, and hot tub. Just minutes from Santa Cruz's Contemporary Art Museum, enjoy complimentary breakfast and WiFi after exploring nearby cultural attractions.
The price is $57
$57 total
Jun 17 - Jun 18
HOTEL OSHO

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (114 reviews)
This luxurious Santa Cruz hotel offers both outdoor and children's pools plus a hot tub for relaxation. Kids stay entertained at the free club while adults unwind at the bar. Near Parque Ecológico with free breakfast, WiFi, and parking.
The price is $95
$95 total
Jun 17 - Jun 18
Novotel Santa Cruz De La Sierra

Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (89 reviews)
Just steps from Ventura Mall and a short drive from the Santa Cruz Zoo, this welcoming hotel features free WiFi and room service. Daily housekeeping ensures a refreshing stay while the international airport is only 26 minutes away.
The price is $49
$49 total
Jun 4 - Jun 5
Delfines Collection Hotel By Mercure

Alfonsina Hotel Boutique by Inboccaluppo

Alfonsina Hotel Boutique by Inboccaluppo
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (43 reviews)
Bask in the Bolivian sunshine at the outdoor pool before enjoying a cocktail at the bar. Minutes from Santa Cruz Zoo and free breakfast, parking, and WiFi elevate your stay at this fitness-equipped retreat.
The price is $80
$80 total
May 26 - May 27
Alfonsina Hotel Boutique by Inboccaluppo

Apart Hotel Toborochi

Apart Hotel Toborochi
3.0 star property
Santa Cruz
8.8 out of 10, Excellent, (60 reviews)
Escape to this refined Santa Cruz aparthotel where you'll enjoy an outdoor pool and onsite spa services. Every apartment includes a private balcony, fully equipped kitchen, and flat-screen TV. Municipal Library and Patio Design LifeStyle Center are located nearby.
The price is $135
$135 total
May 19 - May 20
Apart Hotel Toborochi

Yotau All Suites Hotel

Yotau All Suites Hotel
3.5 star property
Santa Cruz
7.0 out of 10, Good, (76 reviews)
The price is $113
$113 total
May 19 - May 20
Yotau All Suites Hotel

Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (87 reviews)
Immerse yourself in this entertainment district gem near Ventura Mall. Unwind at the full-service spa, cool off in the outdoor pool with cocktails from the poolside bar, or dine at the restaurant after exploring Santa Cruz Zoo.
The price is $126
$126 total
Jun 2 - Jun 3
Swissôtel Santa Cruz De La Sierra

Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (64 reviews)
Immerse in eco-conscious luxury at this Santa Cruz retreat offering 2 on-site dining options and a relaxed bar/lounge. Explore nearby Ventura Mall and Patio Design LifeStyle Center, then unwind with complimentary WiFi and attentive 24-hour service.
The price is $54
$54 total
May 19 - May 20
Chairú Eco Hotel
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Check out hotels with a pool in Santa Cruz

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit Santa Cruz?

Our prices for hotels in Santa Cruz are cheapest in February
Price trends for hotels in Santa Cruz
Pricing is based on two traveler single night rates
View properties in May
Currently viewing crowd sizes and weather for May.
Typical weather for Santa Cruz
May
High 25°C / low 18°C. Sunny most days.
View properties in May
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May, no crowd data, average high temperature 25 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
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June, no crowd data, average high temperature 24 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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July, no crowd data, average high temperature 25 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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August, no crowd data, average high temperature 28 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
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September, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 32 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
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November, no crowd data, average high temperature 32 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
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December, no crowd data, average high temperature 31 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
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January, no crowd data, average high temperature 31 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
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February, no crowd data, average high temperature 29 degrees Celsius, average low temperature 22 degrees Celsius. Cloudy most days.
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March, no crowd data, average high temperature 29 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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April, no crowd data, average high temperature 28 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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Monthly weather averages (˚C)

Top neighborhoods in Santa Cruz

Top landmarks in Santa Cruz

Learn more about Santa Cruz

Santa Cruz is applauded for its cultural attractions such as Sacred Art Museum and Ethno-folkloric Museum.

Check out reviews of Santa Cruz hotels guests love

Frequently asked questions

What hotels do travelers recommend in Santa Cruz?
Where can I find free parking at my hotel in Santa Cruz?
These hotels offer the perk of free parking: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Hotel LP Equipetrol and Swissôtel Santa Cruz De La Sierra. There are 8 options you may want to check out on our site.
Can I book refundable hotels in Santa Cruz?
If you want the flexibility to change your plans to Santa Cruz, most accommodations offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Santa Cruz if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, browse our selection of 21 vacation homes. In addition, you can choose from 187 apartments.
What will the weather in Santa Cruz be like during my trip?
Santa Cruz is a great place to visit to enjoy the sunshine any time of year with an average temp of 70°F.
Why should I book my Santa Cruz accommodation with Hotels.com?
There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.