Hotels in Santa Isabel

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Next weekend
In two weeks

Where to stay in Santa Isabel?

1. Hacienda Villa Sotomayor

Hacienda Villa Sotomayor
2.5 star property
Adjuntas
8.8 out of 10, Excellent, (313 reviews)
The price is $64
$79 total
includes taxes & fees
Nov 16 - Nov 17
Hacienda Villa Sotomayor

2. Casa Patriota

Casa Patriota
2.0 star property
Lares
9.2 out of 10, Wonderful, (10 reviews)
The price is $53
$68 total
includes taxes & fees
Nov 3 - Nov 4
Casa Patriota

3. Casa Grande Mountain Retreat - Adults Only

Casa Grande Mountain Retreat - Adults Only
3.0 star property
Utuado
9.4 out of 10, Exceptional, (264 reviews)
The price is $140
$169 total
includes taxes & fees
Nov 4 - Nov 5
Casa Grande Mountain Retreat - Adults Only

4. Hotel Vista Verde

Hotel Vista Verde
3.0 star property
Yauco
8.6 out of 10, Excellent, (338 reviews)
Escape to this peaceful Yauco hotel featuring 2 outdoor pools, a children's pool, and stunning views from the rooftop terrace. Enjoy meals at 2 restaurants, drinks at 2 bars, and explore nearby Río Loco and Lucchetti Lakes with complimentary breakfast and parking.
The price is $117
$133 total
includes taxes & fees
Nov 3 - Nov 4
Hotel Vista Verde

5. Arecibo Inn

Arecibo Inn
3.0 star property
Arecibo
8.0 out of 10, Very good, (1,037 reviews)
Unwind on the rooftop terrace while taking in Caribbean vistas. This hotel offers 2 outdoor pools, a children's splash area, and rejuvenating spa services. Near Cano Tiburones Nature Reserve, enjoy complimentary breakfast and parking before exploring nearby Playa Caza y Pesca.
The price is $102
$111 total
includes taxes & fees
Nov 4 - Nov 5
Arecibo Inn

6. Costa Bahia Hotel & Convention Center

Costa Bahia Hotel & Convention Center
3.5 star property
Guayanilla
8.8 out of 10, Excellent, (2,231 reviews)
The price is $138
$165 total
includes taxes & fees
Nov 3 - Nov 4
Costa Bahia Hotel & Convention Center

7. Hotel El Guajataca

Hotel El Guajataca
3.5 star property
Quebradillas
8.4 out of 10, Very good, (1,008 reviews)
The price is $90
$99 total
includes taxes & fees
Nov 3 - Nov 4
Hotel El Guajataca

8. Hacienda Doña Minga

Hacienda Doña Minga
3.0 star property
Adjuntas
9.6 out of 10, Exceptional, (20 reviews)
The price is $250
$273 total
includes taxes & fees
Nov 3 - Nov 4
Hacienda Doña Minga

9. Royal Delonix Hotel

Royal Delonix Hotel
3.0 star property
Penuelas
9.2 out of 10, Wonderful, (597 reviews)
Escape to this welcoming retreat featuring an inviting outdoor pool and restaurant in Peñuelas. The helpful staff creates a memorable stay while you explore nearby Guayanilla Bay. Unwind with a drink at the bar after day trips to Hacienda Buena Vista.
The price is $89
$108 total
includes taxes & fees
Nov 12 - Nov 13
Royal Delonix Hotel

10. Vacation Rental Arecibo PR

Vacation Rental Arecibo PR
2.0 star property
Arecibo
8.4 out of 10, Very good, (231 reviews)
This cozy vacation rental offers free WiFi and parking in Arecibo. Conveniently located near Caribbean Cinemas Arecibo and Plaza Del Norte, you'll enjoy comfortable accommodations with housekeeping services during your Puerto Rico adventure.
The price is $78
$85 total
includes taxes & fees
Nov 3 - Nov 4
Vacation Rental Arecibo PR

11. Parador El Buen Café

Parador El Buen Café
3.0 star property
Hatillo
8.6 out of 10, Excellent, (1,001 reviews)
Discover this Hatillo hotel steps from Puerto Rico's finest beaches, with an inviting outdoor pool and international cuisine at the on-site café. Convenient to shopping centers and main roads, with attentive staff to enhance your coastal getaway.
The price is $152
$162 total
includes taxes & fees
Nov 8 - Nov 9
Parador El Buen Café

12. Casa Campo Bed and Breakfast

Casa Campo Bed and Breakfast
2.5 star property
San Sebastian
9.8 out of 10, Exceptional, (74 reviews)
Feel the serenity at this countryside B&B in San Sebastian with an inviting outdoor pool and terrace. Near popular attractions like Casa Santo Domingo, this retreat offers free WiFi, parking, and garden views, plus refreshments at the bar.
The price is $165
$177 total
includes taxes & fees
Nov 4 - Nov 5
Casa Campo Bed and Breakfast

13. San Sebastian Bed & Breakfast

San Sebastian Bed & Breakfast
3.5 star property
San Sebastian
9.0 out of 10, Wonderful, (54 reviews)
The price is $130
$142 total
includes taxes & fees
Nov 3 - Nov 4
San Sebastian Bed & Breakfast

14. Caño Tiburones Guest House

Caño Tiburones Guest House
3.0 star property
Arecibo
9.2 out of 10, Wonderful, (57 reviews)
The price is $104
$113 total
includes taxes & fees
Nov 3 - Nov 4
Caño Tiburones Guest House

15. Hotel Nuevo Mejico

Hotel Nuevo Mejico
3.5 star property
Ponce
8.0 out of 10, Very good, (948 reviews)
This well-positioned Ponce motel offers complimentary WiFi and parking, plus convenient 24-hour room service for late-night needs. Nearby attractions include the fascinating Tibes Indian Ceremonial Center and scenic El Vigia Hill.
The price is $83
$90 total
includes taxes & fees
Nov 3 - Nov 4
Hotel Nuevo Mejico

16. Hostal Universitario

Hostal Universitario
2.0 star property
San German
9.0 out of 10, Wonderful, (227 reviews)
This lively hostal in San Germán puts you near Casa de Lola Rodríguez de Tió and the town's cathedral. Rooms include refrigerators and microwaves while a garden and terrace offer relaxation spots. Enjoy kayaking and diving options with helpful staff to guide your stay.
The price is $70
$76 total
includes taxes & fees
Nov 3 - Nov 4
Hostal Universitario

17. Ventana al Atlantico at Arecibo 681 Ocean Drive

Ventana al Atlantico at Arecibo 681 Ocean Drive
2.5 star property
Arecibo
7.0 out of 10, Good, (301 reviews)
Seaside sanctuary in Arecibo featuring an outdoor pool and garden terrace. Each apartment includes convenient refrigerators and microwaves, with hiking trails nearby. Free WiFi and parking enhance your stay near Playa Caza y Pesca and Cave of the Indian.
The price is $109
$154 total
includes taxes & fees
Nov 3 - Nov 4
Ventana al Atlantico at Arecibo 681 Ocean Drive

18. Arecibo Hotel 2105

Arecibo Hotel 2105
2.0 star property
Arecibo
7.8 out of 10, Good, (23 reviews)
Escape to this tranquil apartment near Playa El Muelle. Enjoy modern amenities including a Smart TV with Netflix after exploring local attractions. The outdoor terrace offers a perfect spot to unwind while free WiFi and parking add convenience to your stay.
The price is $125
$174 total
includes taxes & fees
Nov 3 - Nov 4
Arecibo Hotel 2105

19. Royal Isabela

Royal Isabela
4.5 star property
Isabela
9.6 out of 10, Exceptional, (200 reviews)
The price is $446
$583 total
includes taxes & fees
Nov 18 - Nov 19
Royal Isabela

20. Casa vacacional en Arenales Isabela

Casa vacacional en Arenales Isabela
3.5 star property
Isabela
9.0 out of 10, Wonderful, (50 reviews)
Embrace the tranquil garden atmosphere of this welcoming vacation home in Isabela. Just minutes from Carribbean Cinemas and Paseo Lineal, enjoy free WiFi and parking while the fully-equipped kitchen makes vacation dining effortless.
The price is $70
$195 total
includes taxes & fees
Nov 8 - Nov 9
Casa vacacional en Arenales Isabela
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Check out reviews of Santa Isabel hotels guests love

Frequently asked questions

What accommodations do travelers like in Santa Isabel?
Can I book a refundable hotel in Santa Isabel?
If you need the flexibility to change your travel plans to Santa Isabel, most accommodations offer refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Santa Isabel be like during my vacation?
With an average temperature of 76°F during the coldest months, Santa Isabel is a great place to visit any time of year.
Why should I book my Santa Isabel accommodation with Hotels.com?
There are plenty of reasons to book your Santa Isabel travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.