Hotels in Santa Cruz Island

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Maidith Galapagos Inn
Maidith Galapagos Inn
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (132 reviews)
Immerse yourself in nature at this Puerto Ayora sanctuary with outdoor and children's pools. Just steps from Galápagos National Park, the hotel offers delicious breakfast and helpful staff. Fishing Piers and Gus Angermeyer Ferry Terminal are nearby.
The price is $122
$122 total
May 7 - May 8
Maidith Galapagos Inn
Semilla Verde Boutique Hotel
Semilla Verde Boutique Hotel
3.5 star property
Bella Vista
9.8 out of 10, Exceptional, (62 reviews)
Surrounded by Galápagos National Park, this boutique hotel offers an outdoor pool and rejuvenating massages. Enjoy complimentary breakfast and parking while exploring nearby Rancho El Manzanillo and Lava Tunnel attractions.
The price is $176
$193 total
May 4 - May 5
Semilla Verde Boutique Hotel
Blu Galapagos Sustainable Waterfront Lodge
Blu Galapagos Sustainable Waterfront Lodge
4.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (130 reviews)
Surrounded by natural wonder at this Puerto Ayora waterfront lodge with international dining at Almar by Isla Grill. Explore Galápagos National Park just steps away or visit nearby Charles Darwin Research Station using complimentary bikes.
The price is $218
$240 total
May 16 - May 17
Blu Galapagos Sustainable Waterfront Lodge
Capitan Max B&B
Capitan Max B&B
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (226 reviews)
Wake up to complimentary continental breakfast at this Puerto Ayora retreat near Malecon and Las Ninfas Lagoon. Fellow travelers praise the helpful staff while free WiFi and parking enhance your Galápagos adventure.
The price is $77
$77 total
May 4 - May 5
Capitan Max B&B
Posada del Mar
Posada del Mar
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (236 reviews)
This Puerto Ayora gem combines a safe, central location with proximity to Malecon and Gus Angermeyer Ferry Terminal. Guests consistently praise the helpful team while enjoying convenient daily housekeeping and laundry services during their Galápagos adventure.
The price is $83
$83 total
May 4 - May 5
Posada del Mar
Angermeyer Waterfront Inn
Angermeyer Waterfront Inn
3.5 star property
Puerto Ayora
9.4 out of 10, Exceptional, (133 reviews)
The price is $282
$310 total
May 17 - May 18
Angermeyer Waterfront Inn
Galapagos Dreams
Galapagos Dreams
3.0 star property
Puerto Ayora
9.0 out of 10, Wonderful, (139 reviews)
Embrace the natural wonder at this Puerto Ayora hostal next to Galápagos National Park. Unwind with massages at the full-service spa, sip drinks at the bar, or enjoy the terrace. The Gus Angermeyer Ferry Terminal and Fishing Piers are just minutes away.
The price is $82
$90 total
Jun 1 - Jun 2
Galapagos Dreams
Hotel Fiesta
Hotel Fiesta
3.5 star property
Puerto Ayora
9.0 out of 10, Wonderful, (405 reviews)
Cool off in the outdoor pool or relax in one of 3 hot tubs at this Puerto Ayora retreat. Enjoy drinks at the poolside bar, dine at the on-site restaurant, and explore nearby Las Ninfas Lagoon and Malecon. The attentive staff ensures a memorable Galápagos adventure.
The price is $155
$155 total
May 5 - May 6
Hotel Fiesta
Suymar Ecolodge Galapagos
Suymar Ecolodge Galapagos
3.0 star property
Bella Vista
9.2 out of 10, Wonderful, (19 reviews)
Unwind at this peaceful ecolodge with 2 restaurants and bars, plus a relaxing outdoor pool and spa. Free breakfast, WiFi and parking complement your stay, while nearby Fishing Piers and Charles Darwin Research Station await exploration.
The price is $117
$117 total
May 4 - May 5
Suymar Ecolodge Galapagos
La Peregrina Bed & Breakfast
La Peregrina Bed & Breakfast
2.5 star property
Puerto Ayora
9.0 out of 10, Wonderful, (34 reviews)
Just steps from Galápagos National Park, this cozy B&B offers complimentary breakfast and daily housekeeping. Explore nearby Fishing Piers or catch a ferry at Gus Angermeyer Terminal after relaxing in the garden retreat.
The price is $151
$151 total
May 4 - May 5
La Peregrina Bed & Breakfast
Enchanted Galapagos Lodge
Enchanted Galapagos Lodge
3.0 star property
Bella Vista
8.0 out of 10, Very Good, (3 reviews)
The price is $224
$224 total
May 4 - May 5
Enchanted Galapagos Lodge
El Barranco Galapagos
El Barranco Galapagos
2.5 star property
Puerto Ayora
9.8 out of 10, Exceptional, (65 reviews)
Immerse yourself in Puerto Ayora's natural beauty at this Mediterranean hotel with an outdoor pool and hot tub. Steps from Galápagos National Park, enjoy free breakfast and WiFi while exploring nearby Malecon and the ferry terminal.
The price is $276
$276 total
May 4 - May 5
El Barranco Galapagos
Twin Hotel Galapagos
Twin Hotel Galapagos
3.0 star property
Bella Vista
8.4 out of 10, Very Good, (46 reviews)
Escape to a verdant sanctuary with Regional cuisine at Las Gemelas restaurant and refreshing dips in the outdoor pool. Near Charles Darwin Research Station, this Bella Vista gem offers free breakfast, WiFi, and convenient parking.
The price is $118
$118 total
May 4 - May 5
Twin Hotel Galapagos
Hotel Palace Galapagos
Hotel Palace Galapagos
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (110 reviews)
Just steps from Galápagos National Park, this Puerto Ayora hotel offers free WiFi and a garden. Enjoy nearby hiking trails, scuba diving, and snorkeling adventures. Fishing Piers and Gus Angermeyer Ferry Terminal add to the exploration options.
The price is $81
$81 total
May 5 - May 6
Hotel Palace Galapagos
Natura Gardens Galápagos Hotel
Natura Gardens Galápagos Hotel
3.0 star property
Bella Vista
6.0 out of 10, (5 reviews)
Unwind at this Bella Vista retreat offering massages, outdoor pool, and a poolside bar surrounded by lush gardens. Just steps from Galápagos National Park with Charles Darwin Research Station nearby. Daily housekeeping and free breakfast enhance your island adventure.
The price is $165
$165 total
May 4 - May 5
Natura Gardens Galápagos Hotel
Hotel Cucuve
Hotel Cucuve
4.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (289 reviews)
Wake up to complimentary continental breakfast at this welcoming B&B near Fishing Piers and Gus Angermeyer Ferry Terminal. Enjoy snorkeling adventures nearby, relax on the terrace, or grab a bite at the snack bar after exploring the national park.
The price is $187
$206 total
May 4 - May 5
Hotel Cucuve
Royal Palm Galapagos, Curio Collection Hotel by Hilton
Royal Palm Galapagos, Curio Collection Hotel by Hilton
4.5 star property
Santa Rosa
9.4 out of 10, Exceptional, (57 reviews)
Immerse yourself in natural wonder at this Santa Rosa sanctuary bordering Galápagos National Park. Unwind with deep-tissue massages or swim in the outdoor pool. Savor meals at 2 restaurants including The Highland Cafe, then explore nearby Los Gemelos Sinkholes.
The price is $248
$273 total
May 6 - May 7
Royal Palm Galapagos, Curio Collection Hotel by Hilton
Ikala Galapagos Hotel
Ikala Galapagos Hotel
4.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (145 reviews)
Tropical elegance awaits at this Puerto Ayora gem with an outdoor pool and poolside bar. Enjoy local cuisine at Ikala La Terraza after exploring nearby Malecon. Staff earn rave reviews for exceptional service in clean, comfortable rooms.
The price is $204
$225 total
May 5 - May 6
Ikala Galapagos Hotel
Hotel La Isla
Hotel La Isla
3.5 star property
Puerto Ayora
9.6 out of 10, Exceptional, (68 reviews)
Wake up to complimentary breakfast at this Puerto Ayora hotel before exploring Galápagos National Park just steps away. After snorkeling adventures, unwind on the rooftop terrace with island views. Fishing Piers and ferry access nearby.
The price is $180
$198 total
May 5 - May 6
Hotel La Isla
Hotel Galapagos Suites
Hotel Galapagos Suites
2.5 star property
Puerto Ayora
10.0 out of 10, Exceptional, (11 reviews)
Wake up to complimentary local cuisine breakfast at this Puerto Ayora hotel near Galápagos National Park. Just a short distance from Fishing Piers and Gus Angermeyer Ferry Terminal, you'll enjoy free WiFi while exploring Ecuador's natural paradise.
The price is $106
$116 total
May 9 - May 10
Hotel Galapagos Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Check out family-friendly hotels in Santa Cruz Island

You can also stay at hotels with a hot tub in Santa Cruz Island

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Santa Cruz Island

Learn more about Santa Cruz Island

Santa Cruz Island is well-known for its attractions such as Charles Darwin Research Station and Malecon. Visitors to this beachside city speak highly of the restaurants whereas sights include Playa de los Alemanes and Tortuga Bay Beach.

Galapagos Marine Iguana walking and swimming on Tortuga bay. Marine iguanas on beach on Santa Cruz Island, Galapagos Islands. Animals, wildlife and amazing nature in Ecuador, South America

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Frequently asked questions

Why should I book my Santa Cruz Island accommodation with Hotels.com?
There are lots of reasons to book your Santa Cruz Island trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.