Hotels in Santa Cruz Island

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Semilla Verde Boutique Hotel
Semilla Verde Boutique Hotel
3.5 star property
Bella Vista
9.8 out of 10, Exceptional, (61 reviews)
Surrounded by Galápagos National Park, this boutique hotel offers an outdoor pool and rejuvenating massages. Enjoy complimentary breakfast and parking while exploring nearby Rancho El Manzanillo and Lava Tunnel attractions.
Semilla Verde Boutique Hotel
Posada del Mar
Posada del Mar
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (219 reviews)
This Puerto Ayora gem combines a safe, central location with proximity to Malecon and Gus Angermeyer Ferry Terminal. Guests consistently praise the helpful team while enjoying convenient daily housekeeping and laundry services during their Galápagos adventure.
The price is $70
$70 total
Feb 15 - Feb 16
Posada del Mar
Fernandina Hotel & Spa Galápagos
Fernandina Hotel & Spa Galápagos
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (32 reviews)
Unwind at this Puerto Ayora sanctuary featuring an outdoor pool, hot tub, and full-service spa offering massages and facials. Just steps from Galápagos National Park, with fishing piers nearby and a café for post-adventure dining.
The price is $150
$150 total
Feb 19 - Feb 20
Fernandina Hotel & Spa Galápagos
El Barranco Galapagos
El Barranco Galapagos
2.5 star property
Puerto Ayora
9.6 out of 10, Exceptional, (44 reviews)
Immerse yourself in Puerto Ayora's natural beauty at this Mediterranean hotel with an outdoor pool and hot tub. Steps from Galápagos National Park, enjoy free breakfast and WiFi while exploring nearby Malecon and the ferry terminal.
The price is $192
$192 total
Feb 24 - Feb 25
El Barranco Galapagos
Royal Palm Galapagos, Curio Collection Hotel by Hilton
Royal Palm Galapagos, Curio Collection Hotel by Hilton
4.5 star property
Santa Rosa
9.2 out of 10, Wonderful, (54 reviews)
Immerse yourself in natural wonder at this Santa Rosa sanctuary bordering Galápagos National Park. Unwind with deep-tissue massages or swim in the outdoor pool. Savor meals at 2 restaurants including The Highland Cafe, then explore nearby Los Gemelos Sinkholes.
The price is $254
$280 total
Mar 11 - Mar 12
Royal Palm Galapagos, Curio Collection Hotel by Hilton
Maidith Galapagos Inn
Maidith Galapagos Inn
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (110 reviews)
Immerse yourself in nature at this Puerto Ayora sanctuary with outdoor and children's pools. Just steps from Galápagos National Park, the hotel offers delicious breakfast and helpful staff. Fishing Piers and Gus Angermeyer Ferry Terminal are nearby.
The price is $126
$126 total
Feb 16 - Feb 17
Maidith Galapagos Inn
Ikala Galapagos Hotel
Ikala Galapagos Hotel
4.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (131 reviews)
Tropical elegance awaits at this Puerto Ayora gem with an outdoor pool and poolside bar. Enjoy local cuisine at Ikala La Terraza after exploring nearby Malecon. Staff earn rave reviews for exceptional service in clean, comfortable rooms.
The price is $221
$243 total
Feb 15 - Feb 16
Ikala Galapagos Hotel
Hotel Cucuve
Hotel Cucuve
4.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (274 reviews)
Wake up to complimentary continental breakfast at this welcoming B&B near Fishing Piers and Gus Angermeyer Ferry Terminal. Enjoy snorkeling adventures nearby, relax on the terrace, or grab a bite at the snack bar after exploring the national park.
The price is $220
$242 total
Feb 28 - Mar 1
Hotel Cucuve
Angermeyer Waterfront Inn
Angermeyer Waterfront Inn
3.5 star property
Puerto Ayora
9.4 out of 10, Exceptional, (130 reviews)
The price is $265
$292 total
Feb 28 - Mar 1
Angermeyer Waterfront Inn
Blu Galapagos Sustainable Waterfront Lodge
Blu Galapagos Sustainable Waterfront Lodge
4.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (125 reviews)
Surrounded by natural wonder at this Puerto Ayora waterfront lodge with international dining at Almar by Isla Grill. Explore Galápagos National Park just steps away or visit nearby Charles Darwin Research Station using complimentary bikes.
The price is $221
$243 total
Feb 26 - Feb 27
Blu Galapagos Sustainable Waterfront Lodge
Hotel Galapagos Suites
Hotel Galapagos Suites
2.5 star property
Puerto Ayora
10.0 out of 10, Exceptional, (10 reviews)
Wake up to complimentary local cuisine breakfast at this Puerto Ayora hotel near Galápagos National Park. Just a short distance from Fishing Piers and Gus Angermeyer Ferry Terminal, you'll enjoy free WiFi while exploring Ecuador's natural paradise.
The price is $104
$115 total
Feb 18 - Feb 19
Hotel Galapagos Suites
Hotel el descanso del Guia
Hotel el descanso del Guia
3.5 star property
Puerto Ayora
8.8 out of 10, Excellent, (189 reviews)
Mediterranean-inspired retreat in Puerto Ayora featuring an outdoor pool with poolside bar and 24-hour fitness center. Enjoy free breakfast before exploring nearby Las Ninfas Lagoon and Fishing Piers. The helpful staff and rooftop sauna enhance this family-friendly escape.
Hotel el descanso del Guia
La Peregrina Bed & Breakfast
La Peregrina Bed & Breakfast
2.5 star property
Puerto Ayora
9.0 out of 10, Wonderful, (33 reviews)
Just steps from Galápagos National Park, this cozy B&B offers complimentary breakfast and daily housekeeping. Explore nearby Fishing Piers or catch a ferry at Gus Angermeyer Terminal after relaxing in the garden retreat.
The price is $151
$151 total
Feb 18 - Feb 19
La Peregrina Bed & Breakfast
Hotel Palace Galapagos
Hotel Palace Galapagos
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (104 reviews)
Just steps from Galápagos National Park, this Puerto Ayora hotel offers free WiFi and a garden. Enjoy nearby hiking trails, scuba diving, and snorkeling adventures. Fishing Piers and Gus Angermeyer Ferry Terminal add to the exploration options.
The price is $81
$81 total
Feb 15 - Feb 16
Hotel Palace Galapagos
Capitan Max B&B
Capitan Max B&B
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (211 reviews)
Wake up to complimentary continental breakfast at this Puerto Ayora retreat near Malecon and Las Ninfas Lagoon. Fellow travelers praise the helpful staff while free WiFi and parking enhance your Galápagos adventure.
Capitan Max B&B
Twin Hotel Galapagos
Twin Hotel Galapagos
3.0 star property
Bella Vista
8.4 out of 10, Very Good, (45 reviews)
Escape to a verdant sanctuary with Regional cuisine at Las Gemelas restaurant and refreshing dips in the outdoor pool. Near Charles Darwin Research Station, this Bella Vista gem offers free breakfast, WiFi, and convenient parking.
The price is $92
$92 total
Mar 15 - Mar 16
Twin Hotel Galapagos
Hotel Fiesta
Hotel Fiesta
3.5 star property
Puerto Ayora
9.0 out of 10, Wonderful, (390 reviews)
Cool off in the outdoor pool or relax in one of 3 hot tubs at this Puerto Ayora retreat. Enjoy drinks at the poolside bar, dine at the on-site restaurant, and explore nearby Las Ninfas Lagoon and Malecon. The attentive staff ensures a memorable Galápagos adventure.
The price is $155
$155 total
Feb 15 - Feb 16
Hotel Fiesta
Suymar Ecolodge Galapagos
Suymar Ecolodge Galapagos
3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (15 reviews)
Unwind at this peaceful ecolodge with 2 restaurants and bars, plus a relaxing outdoor pool and spa. Free breakfast, WiFi and parking complement your stay, while nearby Fishing Piers and Charles Darwin Research Station await exploration.
Suymar Ecolodge Galapagos
BAY VIEW HOUSE
BAY VIEW HOUSE
3.5 star property
Puerto Ayora
10.0 out of 10, Exceptional, (4 reviews)
Wake to nature's paradise at this Puerto Ayora guesthouse near Malecon and Gus Angermeyer Ferry Terminal. Unwind at the full-service spa after hiking local trails or snorkeling vibrant waters. Free WiFi keeps you connected while daily housekeeping ensures comfort.
The price is $223
$223 total
Feb 18 - Feb 19
BAY VIEW HOUSE
Mainao
Mainao
3.5 star property
Puerto Ayora
9.6 out of 10, Exceptional, (35 reviews)
Wake up to nature at this Puerto Ayora hotel bordering Galápagos National Park. Start your day with free buffet breakfast before exploring nearby Fishing Piers and Gus Angermeyer Ferry Terminal. Free WiFi and 24-hour front desk support your island adventure.
The price is $138
$152 total
Mar 15 - Mar 16
Mainao
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top landmarks in Santa Cruz Island

Learn more about Santa Cruz Island

Santa Cruz Island is well-known for its attractions such as Charles Darwin Research Station and Playa de los Alemanes. Visitors to this beachside city speak highly of the restaurants whereas sights include Las Grietas and Tortuga Bay Beach.

Galapagos Marine Iguana walking and swimming on Tortuga bay. Marine iguanas on beach on Santa Cruz Island, Galapagos Islands. Animals, wildlife and amazing nature in Ecuador, South America

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Frequently asked questions

Why should I book my Santa Cruz Island accommodation with Hotels.com?
There are lots of reasons to book your Santa Cruz Island trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.