Photo by Nico Barner

Hotels in Eastern Panama

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Where to stay in Eastern Panama?

Ciel y Miel

Cacique

$228 total

includes taxes & fees

Jul 16 - Jul 17

Basic Room, Bay View | Individually decorated, free WiFi, bed sheets

Ranchos de Chalia

Puerto Lindo

$139 total

includes taxes & fees

Jul 16 - Jul 17

San Blas Private Beach Cabin

Narganá

$256 total

includes taxes & fees

Jul 17 - Jul 18

Ordovician Beach Resort

Isla Grande

$505 total

includes taxes & fees

Jul 16 - Jul 17

san blas luxury tour

Nusatupo

$152 total

includes taxes & fees

Jul 16 - Jul 17

Private Bedroom on Paradise San Blas Island

Narganá

$183 total

includes taxes & fees

Jul 17 - Jul 18

Konsenda San Blas

El Llano

$74 total

includes taxes & fees

Jul 16 - Jul 17

Discovery Gunayar

Narganá

$119 total

includes taxes & fees

Jul 16 - Jul 17

San Blas Paradise Private Cabins on Shipwreck Island - meals included

Ailigandi

$186 total

includes taxes & fees

Jul 17 - Jul 18

HOTEL ISLA GRANDE

Isla Grande

$109 total

includes taxes & fees

Jul 16 - Jul 17

Basic Cabin, Ocean View | Beach | On the beach, white sand, free beach shuttle

Sanblastourgy

Nargana

$248 total

includes taxes & fees

Jul 16 - Jul 17

Cabins in Asserya Island - San Blas paradise - meals included

Ailigandi

$145 total

includes taxes & fees

Jul 17 - Jul 18

San Blas Private Oceanfront Cabin

Narganá

$385 total

includes taxes & fees

Jul 17 - Jul 18

Private Over-Water Cabins on San Blas Island

Narganá

$330 total

includes taxes & fees

Jul 23 - Jul 24

Basic Cabin, Multiple Beds, Balcony, Sea View | Beach/ocean view

San Blas Tour Aridub

Narganá

$144 total

includes taxes & fees

Jul 16 - Jul 17

Cabins on paradise San Blas island

Narganá

$296 total

includes taxes & fees

Jul 17 - Jul 18

Cabañas Isla Nubesidub San Blas

Narganá

$422 total

includes taxes & fees

Jul 30 - Jul 31

Cocoloco - Catamaran Lagoon 52F SAN BLAS

Narganá

$2,250 total

includes taxes & fees

Jul 16 - Jul 17

Cabañas Nalunega San Blas

Narganá

$391 total

includes taxes & fees

Jul 30 - Jul 31

Private Over-the-Water Cabin in San Blas including Meals

Mirladub

$535 total

includes taxes & fees

Jul 18 - Jul 19

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You can also stay at hotels with a pool in Eastern Panama

Ciel y Miel

Cacique

$228 total

includes taxes & fees

Jul 16 - Jul 17

Private Over-the-Water Cabin in San Blas including Meals

Mirladub

$535 total

includes taxes & fees

Jul 18 - Jul 19

View all properties

Go beyond your typical stay in Eastern Panama

Cabin

Pet friendly

Top landmarks in Eastern Panama

Isla Diablo

Isla Diablo is 1.8 mi (2.9 km) from central San Blas Islands, why not stop by during your stay.

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Learn more about Eastern Panama

Eastern Panama is well-known for its attractions such as Cayos Holandeses and Isla Diablo. The city has something for everyone including sights like Isla Chichime and Chagres National Park within a tropical setting.

See all hotels in Eastern Panama

A calm sea with a small boat and a row of palm trees on the shore.

Check out reviews of Eastern Panama hotels guests love

Ordovician Beach Resort

10/10 Excellent

"This resort is one of those special places you find that redefines a vacation. It is about a 15 minute boat ride from the dock, occupying the back side of Isla Grande and looking out to the Caribbean Sea. We were there during low season in July, and were fortunate enough to be one of just a few visitors staying at the time. The wonderful staff contributed to this being one of our most cherished travel destinations. Ricardo, Jose and Daniel at the restaurants were so incredibly warm and welcoming, in addition to Tiffany and Marcella in the office, and we quickly felt a part of their community. We enjoyed meeting the owners of the resort who introduced themselves over dinner and we’re also incredibly kind and friendly. Overall, the food was delicious, the rooms were clean and spacious, and our boys (10&12) love the games area and resort facilities. We would highly recommend!"

Ciel y Miel

10/10 Excellent

"Ciel y Miel is a beautiful boutique eco-lodge, but it’s important to know what to expect. It’s located inside a national park, so the final road is dirt and very remote. You park at the lower entrance and the staff drives you to the rooms. Our first night was an adjustment after a long drive. The property was very quiet (we visited during the low season), and the jungle sounds took some getting used to. By morning, we realized how peaceful and beautiful it really was. The rooms are spacious and clean with incredible views. The furniture is a little dated, and the room had a musty smell at first, which is common in the humid climate when A/C isn’t running. The infinity pool, beach club, and beach are stunning. The staff will drive you to the beach anytime, and they can arrange a boat trip to an even more secluded beach. I didn’t see 4 pools like advertised but it could be a seasonal thing. The highlight was the staff, especially José Enrique, who went above and beyond to make our stay special. The chef was outstanding—every meal was delicious and worth the price which was a bit high. (Skip the Aperol Spritz.) One suggestion: the listing advertises 4 pools, 3 restaurants, and a spa, but during our stay only 2 pools and 1 restaurant were available. It would be helpful if seasonal amenities were noted. My advice: arrive before sunset, stay at least 2 nights, and embrace the quiet. We left with wonderful memories and would happily return."

Ranchos de Chalia

10/10 Excellent

"Here's a natural, conversational review in English: We had a wonderful stay here. The hotel is beautiful, with an amazing pool overlooking both the ocean and the rainforest. Everything was very clean, and the beds were extremely comfortable. The staff were incredibly friendly and welcoming. The owner even helped arrange transportation for us to a nearby island beach, which we really appreciated. The water was crystal clear and perfect for swimming. The food was also excellent. We have some dietary restrictions, but there were still plenty of delicious options for us. The fried fish was outstanding, the chicken was delicious, and the breakfast was one of the highlights of our stay. We stayed in a smaller room, but it was very comfortable. There was a king-size bed for us, and our adult children each had their own separate bed. I highly recommend this place. Honestly, it’s the kind of destination where you can completely relax and never feel the need to leave the property. It was a true 100% vacation experience."

Frequently asked questions

Why should I book my Eastern Panama hotel with Hotels.com?

There are plenty of reasons to book your Eastern Panama travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.