Photo by Nico Barner

Hotels in Eastern Panama

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Eastern Panama?

Ciel y Miel

Ciel y Miel
3.0 star property
Cacique
10.0 out of 10, Exceptional, (11 reviews)
Bask in seaside luxury at this Cacique hotel offering 3 restaurants and rejuvenating massages. Explore Isla Mamey and Portobelo National Park nearby, then unwind at the beach bar after a dip in 1 of 4 outdoor pools. Free breakfast, WiFi, and valet parking enhance the value.
The price is $207
$228 total
includes taxes & fees
Jul 16 - Jul 17
Ciel y Miel

Ranchos de Chalia

Ranchos de Chalia
3.0 star property
Puerto Lindo
9.8 out of 10, Exceptional, (18 reviews)
Unwind at this waterfront escape with a refreshing outdoor pool and on-site restaurant. Just minutes from Isla Mamey and Portobelo National Park, the hotel offers free breakfast, WiFi, and parking for effortless exploration.
The price is $126
$139 total
includes taxes & fees
Jul 16 - Jul 17
Ranchos de Chalia

San Blas Private Beach Cabin

San Blas Private Beach Cabin
2.5 star property
Narganá
This beachfront cabin provides complimentary breakfast while surrounded by pristine coastal beauty. Museum of the Kuna Nation and Isla Diablo are nearby attractions to explore during your relaxing seaside retreat.
The price is $233
$256 total
includes taxes & fees
Jul 17 - Jul 18
San Blas Private Beach Cabin

Ordovician Beach Resort

Ordovician Beach Resort
4.5 star property
Isla Grande
10.0 out of 10, Exceptional, (12 reviews)
Escape to a private beach paradise with free cabanas and indulgent massages. This luxury resort offers 2 restaurants, 2 bars, and an outdoor pool. Near Isla Mamey and Portobelo National Park, enjoy free breakfast, WiFi, and parking.
The price is $459
$505 total
includes taxes & fees
Jul 16 - Jul 17
Ordovician Beach Resort

san blas luxury tour

san blas luxury tour
2.0 star property
Nusatupo
The price is $135
$152 total
includes taxes & fees
Jul 16 - Jul 17
san blas luxury tour

Private Bedroom on Paradise San Blas Island

Private Bedroom on Paradise San Blas Island
2.5 star property
Narganá
10.0 out of 10, Exceptional, (1 review)
Set in Narganá, this guesthouse offers a beachfront escape with free continental breakfast. After snorkeling adventures, explore nearby Isla Diablo and Museum of the Kuna Nation. An airport shuttle makes island access seamless.
The price is $166
$183 total
includes taxes & fees
Jul 17 - Jul 18
Private Bedroom on Paradise San Blas Island

Konsenda San Blas

Konsenda San Blas
2.0 star property
El Llano
10.0 out of 10, Exceptional, (3 reviews)
Rustic charm awaits at this welcoming hotel with a garden setting. Grab a bite at the coffee shop or snack bar, then unwind with a drink at the lounge. The terrace offers a peaceful spot to enjoy the complimentary breakfast before exploring El Llano.
The price is $68
$74 total
includes taxes & fees
Jul 16 - Jul 17
Konsenda San Blas

Discovery Gunayar

Discovery Gunayar
2.0 star property
Narganá
6.0 out of 10, (1 review)
Feel the calm of Caribbean waters at this coastal retreat in Narganá. Just moments from Isla Chichime and Isla Diablo, you'll enjoy complimentary breakfast daily while experiencing authentic island charm in this beachfront haven.
The price is $108
$119 total
includes taxes & fees
Jul 16 - Jul 17
Discovery Gunayar

San Blas Paradise Private Cabins on Shipwreck Island - meals included

San Blas Paradise Private Cabins on Shipwreck Island - meals included
2.0 star property
Ailigandi
Discover San Blas Paradise with free local cuisine breakfast each morning. Play volleyball, go kayaking, or snorkel in crystal waters near Isla Diablo. These beach cabins offer a tranquil island retreat with easy access to Isla Chichime.
The price is $169
$186 total
includes taxes & fees
Jul 17 - Jul 18
San Blas Paradise Private Cabins on Shipwreck Island - meals included

HOTEL ISLA GRANDE

HOTEL ISLA GRANDE
3.0 star property
Isla Grande
4.2 out of 10, (11 reviews)
Immerse yourself in paradise at this beach hotel on Isla Grande with deep-tissue massages and ocean vibes. Enjoy free breakfast before exploring nearby Isla Mamey or Portobelo National Park, then unwind at the beach bar.
The price is $99
$109 total
includes taxes & fees
Jul 16 - Jul 17
HOTEL ISLA GRANDE

Sanblastourgy

Sanblastourgy
2.0 star property
Nargana
The price is $225
$248 total
includes taxes & fees
Jul 16 - Jul 17
Sanblastourgy

Cabins in Asserya Island - San Blas paradise - meals included

Cabins in Asserya Island - San Blas paradise - meals included
2.0 star property
Ailigandi
Retreat to tropical paradise on Asserya Island with complimentary breakfast and marina access. Museum and Isla Chichime are nearby attractions, perfect for exploring San Blas Islands' natural beauty.
The price is $132
$145 total
includes taxes & fees
Jul 17 - Jul 18
Cabins in Asserya Island - San Blas paradise - meals included

San Blas Private Oceanfront Cabin

San Blas Private Oceanfront Cabin
2.5 star property
Narganá
Wake up to ocean breezes at this coastal cabin in Narganá. Enjoy free breakfast before exploring the beach just steps away. An airport shuttle service makes travel convenient for your peaceful island getaway.
The price is $259
$385 total
includes taxes & fees
Jul 17 - Jul 18
San Blas Private Oceanfront Cabin

Private Over-Water Cabins on San Blas Island

Private Over-Water Cabins on San Blas Island
2.5 star property
Narganá
This beachside cabin offers complimentary continental breakfast and prime access to snorkeling adventures in crystal-clear waters. Museum of the Kuna Nation and Cayos Holandeses are nearby, combining cultural discovery with island beauty.
The price is $209
$330 total
includes taxes & fees
Jul 23 - Jul 24
Private Over-Water Cabins on San Blas Island

San Blas Tour Aridub

San Blas Tour Aridub
2.0 star property
Narganá
Experience the allure of San Blas at this beachside escape in Narganá. Swim in the outdoor pool or play volleyball between trips to pristine shores. Cozy cabins provide a rustic retreat with daily housekeeping and convenient beach shuttles.
The price is $86
$144 total
includes taxes & fees
Jul 16 - Jul 17
San Blas Tour Aridub

Cabins on paradise San Blas island

Cabins on paradise San Blas island
2.0 star property
Narganá
Set on the stunning San Blas island, these cabins offer complimentary breakfast and easy access to the local museum. An airport shuttle service and snack bar enhance this tranquil Narganá retreat.
The price is $269
$296 total
includes taxes & fees
Jul 17 - Jul 18
Cabins on paradise San Blas island

Cabañas Isla Nubesidub San Blas

Cabañas Isla Nubesidub San Blas
2.0 star property
Narganá
The price is $384
$422 total
includes taxes & fees
Jul 30 - Jul 31
Cabañas Isla Nubesidub San Blas

Cocoloco - Catamaran Lagoon 52F SAN BLAS

Cocoloco - Catamaran Lagoon 52F SAN BLAS
3.0 star property
Narganá
Dive into a maritime adventure aboard this catamaran featuring free breakfast and WiFi. Enjoy drinks at the onboard bar or grab bites at the café while exploring nearby Porvenir Museum and Isla Chichime in the breathtaking San Blas Islands.
The price is $2,045
$2,250 total
includes taxes & fees
Jul 16 - Jul 17
Cocoloco - Catamaran Lagoon 52F SAN BLAS

Cabañas Nalunega San Blas

Cabañas Nalunega San Blas
2.0 star property
Narganá
The price is $355
$391 total
includes taxes & fees
Jul 30 - Jul 31
Cabañas Nalunega San Blas

Private Over-the-Water Cabin in San Blas including Meals

Private Over-the-Water Cabin in San Blas including Meals
2.5 star property
Mirladub
Wake up to ocean views from this coastal houseboat in Mirladub. Enjoy a free continental breakfast before exploring nearby Cayos Holandeses or the Museum of the Kuna Nation. Cool off in the outdoor pool or relax on the terrace.
The price is $441
$535 total
includes taxes & fees
Jul 18 - Jul 19
Private Over-the-Water Cabin in San Blas including Meals
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

You can also stay at hotels with a pool in Eastern Panama

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Eastern Panama

Learn more about Eastern Panama

Eastern Panama is well-known for its attractions such as Cayos Holandeses and Isla Diablo. The city has something for everyone including sights like Isla Chichime and Chagres National Park within a tropical setting.

A calm sea with a small boat and a row of palm trees on the shore.
Photo by Nico Barner
Open Photo by Nico Barner

Check out reviews of Eastern Panama hotels guests love

Frequently asked questions

Why should I book my Eastern Panama hotel with Hotels.com?
There are plenty of reasons to book your Eastern Panama travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Keyâ„¢, our rewards program, you will be able to earn and use OneKeyCashâ„¢* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.