Hotels in Southeast Iowa

your current months are February, 2025 and March, 2025.
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March 2025
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Where to stay in Southeast Iowa?

Cobblestone Inn & Suites - Fort Madison
Premium bedding, down comforters, in-room safe, desk

Cobblestone Inn & Suites - Fort Madison

2.5 star property
9.4 out of 10, Exceptional, (527)
The price is $85
$96 total
includes taxes & fees
Jan 21 - Jan 22
Cobblestone Inn & Suites - Fort Madison
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Southeast Iowa

Ripley's Believe or Not has coined Snake Alley as the crookedest road in the world. Built in 1894, cars still maneuver their way from the top to the bottom, an exhilarating experience worth seeking! #localgem

Snake Alley

Learn about the local history of Burlington when you take a trip to Snake Alley. Visit the area's casinos, or simply enjoy its bars.

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Snake Alley

Learn more about Southeast Iowa

Southeast Iowa is well-known for its riverfront and casinos, featuring attractions such as C.E. Richards Arena and Historic Nauvoo. Visitors highlight this family-friendly city's sports while sights include Joseph Smith Historic Site and Nauvoo State Park.

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Frequently asked questions

Can I book a refundable hotel in Southeast Iowa?
If you want the flexibility to change your travel plans to Southeast Iowa, most accommodations offer refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in Southeast Iowa if I want a vacation rental instead of a traditional hotel?
If you want a good alternative to a hotel, browse our selection of 29 vacation homes. You also might want to consider one of 8 apartments or 7 cabins.
Why should I book my Southeast Iowa hotel with Hotels.com?
There are plenty of reasons to book your Southeast Iowa travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.