Hotels in Orangeburg

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Next weekend
In two weeks

Where to stay in Orangeburg?

Tru by Hilton Orangeburg
Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,007 reviews)
The price is $114
$127 total
includes taxes & fees
May 17 - May 18
Tru by Hilton Orangeburg
Travelodge by Wyndham Orangeburg
Travelodge by Wyndham Orangeburg
2.0 star property
Orangeburg
8.2 out of 10, Very Good, (1,009 reviews)
Experience comfort at this Orangeburg motel with clean rooms and helpful 24-hour staff. Located near Smith-Hammond-Middleton Memorial Center and I.P. Stanback Museum & Planetarium, enjoy convenient free WiFi and parking throughout your stay.
The price is $79
$88 total
includes taxes & fees
May 4 - May 5
Travelodge by Wyndham Orangeburg
Fairfield Inn by Marriott Orangeburg
Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very Good, (756 reviews)
Near Smith-Hammond-Middleton Memorial Center, this business-friendly hotel offers free breakfast, WiFi, and parking. Take a refreshing dip in the seasonal outdoor pool or visit the fitness center. Clean rooms and helpful staff create a welcoming atmosphere.
The price is $110
$122 total
includes taxes & fees
May 17 - May 18
Fairfield Inn by Marriott Orangeburg
Southern Lodge 601
Southern Lodge 601
Orangeburg
7.6 out of 10, Good, (4 reviews)
The price is $71
$79 total
includes taxes & fees
Jun 1 - Jun 2
Southern Lodge 601
Spark by Hilton Orangeburg
Spark by Hilton Orangeburg
2.5 star property
Orangeburg
7.8 out of 10, Good, (1,000 reviews)
Wake up refreshed at this Orangeburg hotel where a seasonal outdoor pool awaits your morning swim. The fitness center keeps your routine on track while free breakfast, WiFi, and parking add value. Located near Smith-Hammond-Middleton Memorial Center, with staff ready to assist.
The price is $103
$115 total
includes taxes & fees
May 5 - May 6
Spark by Hilton Orangeburg
Crown Inn By Oyo Orangeburg Hwy 301
Crown Inn By Oyo Orangeburg Hwy 301
2.5 star property
Orangeburg
3.0 out of 10, (7 reviews)
Tucked away on Highway 301, this convenient Orangeburg hotel offers cozy accommodations with complimentary WiFi and parking. Nearby attractions include Edisto Memorial Gardens and South Carolina State College Historic District. Enjoy room service during your stay.
The price is $50
$60 total
includes taxes & fees
May 4 - May 5
Crown Inn By Oyo Orangeburg Hwy 301
Sleep Inn Orangeburg
Sleep Inn Orangeburg
2.5 star property
Orangeburg
7.8 out of 10, Good, (427 reviews)
Feel refreshed at this welcoming Orangeburg hotel with a seasonal outdoor pool and daily continental breakfast from 6-9 AM. Free WiFi and parking add value, while nearby attractions include the Smith-Hammond-Middleton Memorial Center.
The price is $84
$93 total
includes taxes & fees
May 17 - May 18
Sleep Inn Orangeburg
Hampton Inn & Suites Orangeburg
Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (799 reviews)
Just minutes from Smith-Hammond-Middleton Memorial Center, this hotel offers a refreshing outdoor pool and morning workouts in the fitness center. Guests rave about the helpful staff and clean rooms, while free WiFi and parking enhance your stay.
The price is $130
$145 total
includes taxes & fees
May 17 - May 18
Hampton Inn & Suites Orangeburg
SpringHill Suites by Marriott Orangeburg
SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (744 reviews)
Dive into comfort at this Orangeburg hotel with an indoor pool and free perks like WiFi, parking, and breakfast. Helpful staff welcome you near Smith-Hammond-Middleton Memorial Center and I.P. Stanback Museum & Planetarium.
The price is $131
$146 total
includes taxes & fees
May 11 - May 12
SpringHill Suites by Marriott Orangeburg
Orangeburg Inn & Suites
Orangeburg Inn & Suites
2.0 star property
Orangeburg
6.0 out of 10, (61 reviews)
This Orangeburg hotel offers free WiFi and parking with 24-hour front desk service. Visit nearby Edisto Memorial Gardens or South Carolina State College Historic District for local exploration during your stay.
The price is $54
$61 total
includes taxes & fees
May 4 - May 5
Orangeburg Inn & Suites
Holiday Inn Express & Suites Orangeburg by IHG
Holiday Inn Express & Suites Orangeburg by IHG
2.5 star property
Orangeburg
8.6 out of 10, Excellent, (827 reviews)
Relax in the seasonal outdoor pool after a workout in the 24-hour fitness center. This Orangeburg hotel offers clean rooms, free breakfast, WiFi, and parking near Smith-Hammond-Middleton Memorial Center and I.P. Stanback Museum & Planetarium.
The price is $118
$131 total
includes taxes & fees
Jun 3 - Jun 4
Holiday Inn Express & Suites Orangeburg by IHG
Quality Inn & Suites Orangeburg
Quality Inn & Suites Orangeburg
2.5 star property
Orangeburg
6.2 out of 10, (657 reviews)
Wake up to continental breakfast at this Orangeburg hotel where free WiFi and parking add value to your stay. Located in a convenient spot for local dining, you'll find the Smith-Hammond-Middleton Memorial Center nearby. Business travelers appreciate the practical amenities and easy access.
The price is $60
$66 total
includes taxes & fees
May 24 - May 25
Quality Inn & Suites Orangeburg
Super 8 by Wyndham, Orangeburg
Super 8 by Wyndham, Orangeburg
2.0 star property
Orangeburg
7.0 out of 10, Good, (966 reviews)
Wake up refreshed at this welcoming Orangeburg motel offering free WiFi and on-the-go breakfast each morning. Near Smith-Hammond-Middleton Memorial Center and I.P. Stanback Museum, this spot provides free parking and earns praise for its attentive staff.
The price is $60
$67 total
includes taxes & fees
Jun 1 - Jun 2
Super 8 by Wyndham, Orangeburg
Comfort Inn & Suites Orangeburg
Comfort Inn & Suites Orangeburg
2.5 star property
Orangeburg
8.0 out of 10, Very Good, (599 reviews)
This Orangeburg hotel has an indoor pool for year-round swimming and a fitness center for your workout needs. Enjoy complimentary breakfast, WiFi, and parking while being close to Smith-Hammond-Middleton Memorial Center and I.P. Stanback Museum & Planetarium.
The price is $113
$125 total
includes taxes & fees
May 24 - May 25
Comfort Inn & Suites Orangeburg
Suburban Studios Orangeburg
Suburban Studios Orangeburg
2.0 star property
Orangeburg
6.6 out of 10, (20 reviews)
Wake up in a roomy studio with convenient kitchen facilities in Orangeburg. Free WiFi and parking make exploring easy, with Smith-Hammond-Middleton Memorial Center and I.P. Stanback Museum nearby. The 24-hour front desk ensures assistance whenever needed.
The price is $56
$62 total
includes taxes & fees
May 12 - May 13
Suburban Studios Orangeburg
Super 8 by Wyndham Santee
Super 8 by Wyndham Santee
2.0 star property
Santee
6.8 out of 10, (458 reviews)
Overlooking a golf course, this tranquil motel offers a refreshing seasonal outdoor pool and complimentary breakfast served daily. Located near Santee Cooper Country Club, guests enjoy free WiFi and parking during their stay.
The price is $75
$83 total
includes taxes & fees
May 4 - May 5
Super 8 by Wyndham Santee
Travelodge by Wyndham Santee
Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (724 reviews)
The price is $63
$70 total
includes taxes & fees
May 10 - May 11
Travelodge by Wyndham Santee
Econo Lodge Santee
Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (313 reviews)
Located near Santee Cooper Country Club, this hotel offers free WiFi and parking. You'll appreciate the 24-hour front desk service while exploring nearby attractions including Santee National Golf Club.
The price is $63
$70 total
includes taxes & fees
May 25 - May 26
Econo Lodge Santee
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,000 reviews)
Guests love this quiet Santee hotel for its helpful staff and complimentary breakfast. The outdoor pool and health club offer refreshing workout options, while free parking and WiFi add convenience. Golf enthusiasts will appreciate the nearby Santee Cooper Country Club.
The price is $134
$149 total
includes taxes & fees
May 24 - May 25
Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,003 reviews)
The price is $119
$132 total
includes taxes & fees
May 25 - May 26
Hampton Inn Santee-I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Get last-minute hotel deals in Orangeburg and save more

Sign in to unlock great savings.
Showing deals for:May 3 - May 4
Showing deals for:May 4 - May 5

Check out family-friendly hotels in Orangeburg

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit Orangeburg?

Our prices for hotels in Orangeburg are cheapest in December
Price trends for hotels in Orangeburg
Pricing is based on two traveler single night rates
View properties in May
Currently viewing crowd sizes and weather for May.
Typical weather for Orangeburg
May
High 27°C / low 17°C. Sunny most days.
View properties in May
27°
weather_sun
May, no crowd data, average high temperature 27 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
31°
weather_sun
June, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
33°
weather_sun
July, no crowd data, average high temperature 33 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
32°
weather_sun
August, no crowd data, average high temperature 32 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
29°
weather_sun
September, no crowd data, average high temperature 29 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
24°
weather_sun
October, no crowd data, average high temperature 24 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
14°
18°
weather_sun
November, no crowd data, average high temperature 18 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
15°
weather_sun
December, no crowd data, average high temperature 15 degrees Celsius, average low temperature 7 degrees Celsius. Sunny most days.
13°
weather_sun
January, no crowd data, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Sunny most days.
16°
weather_sun
February, no crowd data, average high temperature 16 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
19°
weather_sun
March, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
23°
weather_sun
April, no crowd data, average high temperature 23 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
Monthly weather averages (˚C)

Top landmarks in Orangeburg

Orangeburg and related destinations

Between moss-draped oaks, Orangeburg reveals its civil rights legacy at the Cecil Williams Museum, where powerful photographs tell stories of struggle and triumph. Edisto Memorial Gardens offers a peaceful retreat with vibrant roses and winding waterways perfect for afternoon contemplation. The historic campuses of South Carolina State and Claflin universities anchor the city with scholarly gravitas and architectural beauty. Sports enthusiasts can catch thrilling games at the Smith-Hammond-Middleton Memorial Center, where local passion fills the stands. For a cosmic perspective, the I.P. Stanback Museum & Planetarium combines art with astronomy in unexpected ways. The town's trading post origins from 1704 have evolved into a place where history feels tangibly present at every corner.

Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Check out reviews of Orangeburg hotels guests love

Frequently asked questions

What accommodations do travelers like in Orangeburg?
Can I book a refundable hotel in Orangeburg?
If you need the flexibility to change your plans to Orangeburg, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Orangeburg if I'm looking for a budget-friendly accommodation?
Where can I stay in Orangeburg if I want a vacation home instead of a hotel?
If you're looking for a good alternative to a hotel, review our selection of 15 vacation homes.
What will the weather in Orangeburg be like during my visit?
July and August are typically the warmest months in Orangeburg when the average temp is 79°F. January and February are the coldest months when the average temperature is 51°F. August and July are the months with the most rain.
Why should I book my Orangeburg hotel through Hotels.com?
There are lots of reasons to book your Orangeburg trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.