Hotels in Seneca

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Best Western Seneca-Clemson
Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very Good, (646 reviews)
Located within a 10-minute drive of Clemson University, this Seneca hotel offers a seasonal outdoor pool and free daily breakfast. Guests appreciate the helpful staff and clean rooms, while enjoying convenient access to local attractions.
The price is $98
$108 total
includes taxes & fees
Feb 8 - Feb 9
Best Western Seneca-Clemson
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (676 reviews)
Just 5 minutes from Lake Keowee, this hotel offers a 24-hour fitness center and seasonal outdoor swimming. Enjoy complimentary breakfast, WiFi, and parking while staying close to Clemson University. Guests consistently praise the helpful staff and clean accommodations.
The price is $123
$136 total
includes taxes & fees
Feb 8 - Feb 9
Hampton Inn & Suites Seneca-Clemson Area
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
Seneca
9.4 out of 10, Exceptional, (206 reviews)
Minutes from Clemson University and Lakes Keowee and Hartwell, this Seneca hotel offers free breakfast and parking. Refresh at the outdoor pool or fitness center after exploring nearby Golden Corner Plaza and Gignilliat Community Center.
The price is $125
$138 total
includes taxes & fees
Feb 8 - Feb 9
Fairfield Inn & Suites Seneca Clemson Univ Area
Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very Good, (673 reviews)
Serene hotel within a 15-minute drive of Clemson University offers a seasonal outdoor pool, complimentary WiFi, parking, and breakfast. Toy Train Park and The Gauntlet attractions are nearby, with guests consistently praising the quiet atmosphere and attentive service.
The price is $78
$92 total
includes taxes & fees
Feb 8 - Feb 9
Quality Inn Seneca Clemson Area US-123
Days Inn by Wyndham Seneca / Clemson Area
Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (724 reviews)
This Seneca motel offers easy access to Clemson University and Lake Keowee. Take a refreshing dip in the seasonal outdoor pool after exploring nearby Lake Hartwell. Free WiFi, parking, and daily on-the-go breakfast add exceptional value.
The price is $69
$76 total
includes taxes & fees
Feb 4 - Feb 5
Days Inn by Wyndham Seneca / Clemson Area
Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,003 reviews)
Unwind at this lakeside retreat with a poolside bar and seasonal outdoor pool just minutes from Clemson University. The 24-hour fitness center and hot tub provide recreation options while the restaurant and lounge offer on-site dining convenience.
The price is $109
$135 total
includes taxes & fees
Feb 3 - Feb 4
Lakeside Lodge Clemson
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (805 reviews)
This convenient Seneca hotel offers a complimentary morning meal, fitness center, and free parking just 5 minutes from campus. Guests praise the attentive staff, while Littlejohn Coliseum and Sloan Tennis Center are located nearby.
The price is $106
$116 total
includes taxes & fees
Feb 8 - Feb 9
Tru by Hilton Seneca Clemson
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (57 reviews)
Tucked between Lake Hartwell and Lake Keowee, these charming cabins offer serene patios and well-equipped kitchenettes. Just minutes from outdoor recreation areas and Cross Creek Plantation Golf, with free parking and cozy climate control for year-round comfort.
The price is $76
$127 total
includes taxes & fees
Feb 8 - Feb 9
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Hampton Inn Clemson-University Area
Hampton Inn Clemson-University Area
2.5 star property
Clemson
8.8 out of 10, Excellent, (627 reviews)
Unwind at this well-positioned hotel near Larry W. Abernathy Waterfront Park, offering a seasonal outdoor pool for morning swims. Free breakfast, WiFi, and parking await, with Clemson Station just a 19-minute walk away.
The price is $111
$124 total
includes taxes & fees
Feb 24 - Feb 25
Hampton Inn Clemson-University Area
Clemson University's James F. Martin Inn
Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.6 out of 10, Exceptional, (966 reviews)
Set on the grounds of Clemson University, this welcoming hotel offers direct access to Walker Golf Course, a seasonal outdoor pool, and poolside bar. Enjoy American cuisine at Sole on the Green or squeeze in a workout at the 24-hour fitness center while exploring campus.
The price is $149
$165 total
includes taxes & fees
Feb 3 - Feb 4
Clemson University's James F. Martin Inn
The Abernathy of Clemson
The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (562 reviews)
Experience Southern hospitality at this refined Clemson hotel just minutes from campus attractions. Unwind with a cocktail at the stylish bar after exploring nearby Sloan Tennis Center and Littlejohn Coliseum. Free parking and convenient location make this an ideal collegiate getaway.
The price is $159
$176 total
includes taxes & fees
Feb 3 - Feb 4
The Abernathy of Clemson
The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (756 reviews)
Moments from Lake Hartwell, this hotel blends walkable access to campus with comfort. Enjoy attentive service, a welcoming restaurant, and stylish bar where you can unwind. Just a 13-minute walk from Clemson Station connects you to broader adventures.
The price is $199
$221 total
includes taxes & fees
Feb 3 - Feb 4
The Shepherd Hotel Downtown Clemson
Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very Good, (1,003 reviews)
Walking distance from Clemson Station, this welcoming hotel sits just 5 minutes from the university campus. After a free breakfast, cool off in the seasonal outdoor pool or hit the 24-hour fitness center. Nearby attractions and quiet, comfortable rooms await.
The price is $101
$112 total
includes taxes & fees
Feb 8 - Feb 9
Best Western Plus Clemson Hotel & Conference Center
Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very Good, (1,003 reviews)
Take a dip in the seasonal outdoor pool at this Clemson hotel, just a 15-minute drive from Clemson University. Enjoy free breakfast, parking, and fitness center access, with African American Museum and Waterfront Park nearby.
The price is $101
$112 total
includes taxes & fees
Feb 8 - Feb 9
Comfort Inn & Suites Clemson - University Area
Inn @ Clemson
Inn @ Clemson
2.5 star property
Clemson
8.2 out of 10, Very Good, (1,002 reviews)
Take advantage of the complimentary breakfast, WiFi and parking at this hotel near Lake Hartwell and Clemson University. Guests praise the helpful staff, clean rooms and quiet environment. The fitness center adds value for active travelers.
The price is $89
$99 total
includes taxes & fees
Feb 8 - Feb 9
Inn @ Clemson
Holiday Inn Express & Suites Clemson by IHG
Holiday Inn Express & Suites Clemson by IHG
2.5 star property
Clemson
8.8 out of 10, Excellent, (957 reviews)
Minutes from Clemson University and Lake Hartwell, this hotel offers complimentary WiFi, parking, and breakfast. Work out in the fitness center before exploring nearby attractions like the African American Museum and waterfront park.
The price is $123
$137 total
includes taxes & fees
Feb 15 - Feb 16
Holiday Inn Express & Suites Clemson by IHG
Clemson Memorabilia House
Clemson Memorabilia House
3.0 star property
Clemson
9.8 out of 10, Exceptional, (9 reviews)
Experience cozy comfort in this well-appointed cottage featuring a full kitchen and washer/dryer. Just 5 minutes from Clemson University and Lake Hartwell, with free WiFi and parking. The balcony offers a perfect spot to unwind after exploring nearby South Carolina Botanical Gardens.
The price is $89
$238 total
includes taxes & fees
Feb 3 - Feb 4
Clemson Memorabilia House
Days Inn by Wyndham Clemson
Days Inn by Wyndham Clemson
3.5 star property
Clemson
7.0 out of 10, Good, (202 reviews)
Just a 5-minute drive from Clemson University, this hotel offers convenient perks including free WiFi, parking, and daily continental breakfast. Nearby attractions include the African American Museum and Larry W. Abernathy Waterfront Park.
The price is $80
$89 total
includes taxes & fees
Feb 4 - Feb 5
Days Inn by Wyndham Clemson
Rodeway Inn & Suites Walhalla
Rodeway Inn & Suites Walhalla
2.0 star property
Walhalla
7.6 out of 10, Good, (175 reviews)
Wake up to complimentary continental breakfast at this welcoming Walhalla motel. Located near Art Circle Gallery and Goldfish Pond, the property offers free WiFi and parking. Just a 22-minute drive from Clemson Station for easy regional exploration.
The price is $68
$76 total
includes taxes & fees
Mar 3 - Mar 4
Rodeway Inn & Suites Walhalla
Courtyard Marriott Clemson
Courtyard Marriott Clemson
3.0 star property
Clemson
9.0 out of 10, Wonderful, (530 reviews)
This business-friendly spot near Clemson Area African American Museum features American cuisine at The Bistro, plus a fitness center and bar. Enjoy free WiFi and parking while staying close to South Carolina Botanical Gardens.
The price is $139
$154 total
includes taxes & fees
Feb 22 - Feb 23
Courtyard Marriott Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Check out pet-friendly hotels in Seneca

You may also like hotels with pools in Seneca

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit Seneca?

Our prices for hotels in Seneca are cheapest in May
Price trends for hotels in Seneca
Pricing is based on two traveler single night rates
View properties in February
Currently viewing crowd sizes and weather for February.
Typical weather for Seneca
February
High 13°C / low 3°C. Partly sunny.
View properties in February
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February, no crowd data, average high temperature 13 degrees Celsius, average low temperature 3 degrees Celsius. Partly sunny.
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March, no crowd data, average high temperature 17 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
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April, no crowd data, average high temperature 22 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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May, no crowd data, average high temperature 26 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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June, no crowd data, average high temperature 31 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
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July, no crowd data, average high temperature 32 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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August, no crowd data, average high temperature 31 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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September, no crowd data, average high temperature 28 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 23 degrees Celsius, average low temperature 12 degrees Celsius. Sunny most days.
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November, no crowd data, average high temperature 17 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
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December, no crowd data, average high temperature 12 degrees Celsius, average low temperature 4 degrees Celsius. Sunny most days.
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January, no crowd data, average high temperature 10 degrees Celsius, average low temperature 1 degrees Celsius. Partly sunny.
Monthly weather averages (˚C)

Top neighborhoods in Seneca

Downtown

Downtown Seneca charms visitors with well-preserved historical buildings that tell the story of its railroad heritage. The tree-lined Ram Cat Alley showcases local history through colorful murals, while the old courthouse square hosts seasonal farmers markets and community events. You can explore the Bertha Lee Strickland Cultural Museum or browse antique shops filled with Southern treasures. Family-owned cafes serve up delicious Southern comfort food like fried green tomatoes and barbecue. Accommodations range from historic bed & breakfasts in Victorian homes to budget-friendly motels. The entire downtown is walkable with wide sidewalks, making it easy to discover this authentic slice of small-town America at your own pace.

Serenity Bay

Lake Keowee beckons from this peaceful coastal retreat nestled in Saxony Forest. Serenity Bay lives up to its name with tree-lined streets perfect for contemplative walks. Nearby Keowee Key Golf Course offers tee times for enthusiasts, while South Beach provides sandy relaxation without the crowds. The natural setting creates an ideal escape for bird watchers and nature photographers. Vacation rentals with weathered wood siding and muted earth tones blend seamlessly into the forest canopy. Getting around requires your own wheels since public transit is limited. The neighborhood trades bustling nightlife for cricket choruses and ocean breezes filtering through pine trees—exactly what makes this hidden gem worth finding.

Pine Ridge Point

Lake Keowee sparkles as the crown jewel of Pine Ridge Point, a peaceful residential haven in Seneca. Waterfront vacation homes nestle among tall pines, offering private docks and stunning views. Visitors spend days swimming in crystal-clear waters, boating across the lake, or simply unwinding on expansive decks beneath Carolina blue skies. This neighborhood is all about authentic lakeside living without commercial distractions. Most travelers cook in well-equipped rental kitchens or drive 15 minutes to Seneca for restaurants. Personal vehicles are essential for getting around, though scenic paths along the shoreline make for perfect evening strolls.

Indian Oaks

Indian Oaks gives you all the peaceful vibes of suburban life with none of the tourist chaos. This leafy neighborhood in Seneca lets you live like a local under a canopy of mature oak trees. The curved streets and manicured lawns create a park-like setting that's perfect for morning walks. Lake Keowee is just a short drive away when you need a water fix. You'll need wheels to get around since public transit is limited and restaurants aren't within walking distance. Most visitors stay in vacation rental homes with private yards and driveways. The neighborhood gets incredibly quiet after dark—ideal for travelers who want to experience authentic suburban living while having Seneca's attractions nearby.

Top landmarks in Seneca

Learn more about Seneca

Between the crystal waters of Lake Keowee and the misty cascade of Isaqueena Falls lies a playground for outdoor enthusiasts. Kayak across the lake while keeping an eye out for bald eagles soaring overhead and blue herons stalking the shallows. The lush forests of Oconee State Park offer hiking trails for every skill level, with shade-dappled paths winding through ancient trees. Twin Lakes Recreation Area provides family-friendly spots to picnic after a morning on the water. Dog owners shouldn't miss The Pier Dog Park, where four-legged friends can splash along the shoreline. After a day of adventure, the coffeehouses in the historic downtown offer the perfect place to recharge while planning tomorrow's excursion to Keowee Key Golf Course or Lake Hartwell.

Lake Keowee South Carolina

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Frequently asked questions

What accommodations do travelers like in Seneca?
Can I book refundable accommodations in Seneca?
If you want the flexibility to change your travel plans to Seneca, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Seneca if I want a budget-friendly accommodation?
Lakeside Lodge Clemson, Tru by Hilton Seneca Clemson and Hampton Inn & Suites Seneca-Clemson Area are a few accommodations you might want to consider that'll save you money.
Where can I stay in Seneca if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, review our selection of 193 vacation homes. In addition, there are 12 apartments and 13 condos.
What will the weather in Seneca be like during my visit?
The warmest months in Seneca are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 46°F. The rainiest months are December and January.
Why should I book my Seneca hotel with Hotels.com?
There are plenty of reasons to book your Seneca travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.