Top 10 Hotels in Neeses, SC in 2026 (from $54)

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Where to stay in Neeses?

A breakfast bar with pastries, fruits, and a vase with flowers.

A Travelodge motel with a parking lot and a signboard.

A hotel bathroom with a sink, mirror, towel rack, and a door leading to the bedroom.

A hotel room with two beds, a nightstand, and two wall-mounted lamps.

1. Travelodge by Wyndham Orangeburg

Orangeburg

$62

$69 total

includes taxes & fees

Oct 21 - Oct 22

A gym with exercise equipment, a mirror, and a black box with an arrow.

A hotel room with a bed, a desk with a chair, a TV mounted on the wall, and a wardrobe.

A pool table with balls, a sofa with cushions, a coffee machine, and a television mounted on the wall.

A self-service food station with a variety of snacks, beverages, and ready-to-eat meals.

2. Tru by Hilton Orangeburg

Orangeburg

$110

$122 total

includes taxes & fees

Nov 8 - Nov 9

A spacious dining area with multiple tables and chairs, a reception desk, and large windows providing natural light.

A hotel room with two beds, a seating area, and a large abstract painting on the wall.

A modern hotel room with a grey sofa, a flat-screen TV, a desk with a lamp, and abstract wall art.

A modern lobby with a wooden ceiling, a central seating area with a round table, and a bar with a variety of bottles.

3. SpringHill Suites by Marriott Orangeburg

Orangeburg

$109

$121 total

includes taxes & fees

Oct 27 - Oct 28

A modern indoor pool area with a table and chairs, large windows, and a poolside lounge with sun loungers.

A modern indoor swimming pool with clear glass walls, sunlit lounge areas, and a view of greenery outside.

A hotel with a modern design, featuring a prominent 'Spark' sign, a well-maintained lawn, and a clear driveway.

A lobby with a reception desk, a staircase, and seating area with orange chairs.

4. Spark by Hilton Orangeburg

Orangeburg

$98

$108 total

includes taxes & fees

Oct 26 - Oct 27

A reception desk with a flat-screen TV, a Dell computer, and a door.

A Red Roof Inn with two red leather armchairs and a small wooden table in front of a stone-patterned wall.

A two-story building with a grey facade, large windows, and a covered entrance area.

A hotel reception area with a counter, coffee machines, and a refrigerator.

5. Red Roof Inn Orangeburg

Orangeburg

$65

$72 total

includes taxes & fees

Oct 21 - Oct 22

A hotel room with a sofa, a bed with a red blanket, two bedside lamps, a small table, and a TV.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A parking lot with multiple cars and a yellow truck.

A motel with a row of single-story rooms, a covered front porch, and a parking lot.

6. Orangeburg Inn & Suites

Orangeburg

$54

$61 total

includes taxes & fees

Oct 25 - Oct 26

A lobby with a reception desk, a sofa, a coffee station, and a flag.

A hotel room with a large bed, a desk, a chair, a nightstand, and a wall-mounted lamp.

A Holiday Inn Express & Suites building with a clear entrance, a covered waiting area, and a landscaped garden.

A modern hotel lobby with a green ceiling, a grey sofa, a patterned ottoman, a wooden bench, and a chair with a geometric throw.

7. Holiday Inn Express & Suites Orangeburg by IHG

Orangeburg

$118

$131 total

includes taxes & fees

Nov 8 - Nov 9

A modern kitchen with a long counter, equipped with coffee makers, a kettle, and a microwave.

A multi-story hotel with a covered entrance, balconies, and a parking area.

A hotel room with a desk, a chair, a flat-screen TV, a refrigerator, a microwave, a lamp, and a large mirror.

A hotel room with a beige armchair, a black ottoman, a standing lamp, and an air conditioning unit.

8. Super 8 by Wyndham, Orangeburg

Orangeburg

$58

$65 total

includes taxes & fees

Nov 18 - Nov 19

A Hampton Inn & Suites hotel with a modern design, featuring a parking lot and a well-lit entrance.

A modern dining area with tables and chairs, large windows with sheer curtains, and pendant lighting.

A snack shop with a sign reading "Hampton Suite Shop" and a variety of snacks and drinks on display.

A gym with treadmills, a bench, and a ball.

9. Hampton Inn & Suites Orangeburg

Orangeburg

$135

$150 total

includes taxes & fees

Nov 8 - Nov 9

A spacious lobby with a sofa, chairs, a coffee table, and a staircase with a green leaf-patterned wall.

A dining area with wooden tables and chairs, a large window with a view, a flat-screen TV, and a vending machine.

A reception area with a staircase, reception desk, and seating area with blue sofas.

A hotel room with a bed, bedside tables, a nightstand, a lamp, a wall-mounted phone, a painting, a window with curtains, and an air conditioning unit.

10. Sleep Inn Orangeburg

Orangeburg

$88

$98 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A spacious living area with a ceiling fan, a sofa, a coffee table, and a TV.

A spacious lobby with a central round table and chairs, a bar area, and a staircase leading to an upper level.

A spacious dining area with a kitchen in the background, featuring a modern design with a ceiling fan, a clock, and a flat-screen TV mounted on the wall.

11. Quality Inn & Suites Orangeburg

Orangeburg

$60

$66 total

includes taxes & fees

Nov 15 - Nov 16

A restaurant with round tables and chairs, a counter with a display case, and large windows.

A hotel room with two beds, a desk, and a mirror.

A reception desk with a laptop, a patterned sofa, and a doormat with "SOUTHERN" visible.

A Southern Lodge building with a covered parking area, brick facade, and signage.

12. Southern Lodge 601

Orangeburg

$73

$81 total

includes taxes & fees

Oct 21 - Oct 22

A stone fireplace with a television mounted above it, a small statue on the mantel, and a wooden cabinet to the left.

A corner market with a refrigerator stocked with beverages and snacks.

A reception area with a wooden reception desk, a welcome mat, a vending machine, and a clock on the wall.

A modern bar area with a stone fireplace, a flat-screen TV, and a coffee station.

13. Fairfield Inn by Marriott Orangeburg

Orangeburg

$101

$112 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with two beds, a desk, and a chair. There are wall-mounted lamps and a large window with curtains.

A restaurant with multiple tables and chairs, a wooden counter, and a painting on the wall.

A Comfort Inn & Suites hotel with a brick facade, multiple windows, and a clear blue sky.

A swimming pool with a 4ft depth marker, lounge chairs, and a covered seating area.

14. Comfort Inn & Suites Orangeburg

Orangeburg

$101

$112 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, a desk, a chair, a sofa, and a table.

A hotel with a swimming pool, outdoor seating, and a flagpole with an American flag.

A Baymont Inn & Suites reception desk with a sign indicating Orangeburg, South Carolina.

A gym with cardio equipment, dumbbells, and a TV on a shelf.

15. Baymont by Wyndham Orangeburg North

Orangeburg

$55

$61 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, a desk, a chair, and a hanging coat rack.

A reception area with a stone wall, wooden reception desk, and a seating area with a TV and plants.

A modern kitchen with a granite countertop, a built-in microwave, a sink, and a mirror above the counter.

A room with two framed pictures on the wall, a table with a coffee machine, bowls, and a mug.

16. Suburban Studios Orangeburg

Orangeburg

$59

$65 total

includes taxes & fees

Nov 18 - Nov 19

A courtyard with a fountain, brick buildings, and outdoor lighting.

A spacious kitchen with a herringbone floor pattern, white cabinetry, and a built-in island.

A multi-story building with a brick facade, multiple balconies, and a landscaped courtyard with pathways and plants.

A panoramic view of a hotel lobby with a curved floor design, a reception desk, a seating area with chairs, and a kitchen area.

17. Winton Inn & Suites

Barnwell

$70

$78 total

includes taxes & fees

Oct 21 - Oct 22

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Go beyond your typical stay in Neeses

Top landmarks in Neeses

Thunder Valley Speedway

Thunder Valley Speedway is 2.1 mi (3.5 km) from central Neeses, why not stop by during your stay.

See properties

Check out reviews of Neeses hotels guests love

Hampton Inn & Suites Orangeburg

Orangeburg

10/10 Exceptional

Kevin

Tru by Hilton Orangeburg

Orangeburg

10/10 Exceptional

Barbara

Holiday Inn Express & Suites Orangeburg by IHG

Orangeburg

10/10 Exceptional

Deborah

Spark by Hilton Orangeburg

Orangeburg

10/10 Exceptional

Aaron

Comfort Inn & Suites Orangeburg

Orangeburg

10/10 Exceptional

Ken

Fairfield Inn by Marriott Orangeburg

Orangeburg

10/10 Exceptional

Barry

Super 8 by Wyndham, Orangeburg

Orangeburg

10/10 Exceptional

Suburban Studios Orangeburg

Orangeburg

10/10 Exceptional

Rhonda

Frequently Asked Questions

Can I book refundable accommodations in Neeses?

If you need the flexibility to change your travel plans to Neeses, most properties offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Neeses be like during my trip?

July and August are typically the warmest months in Neeses when the average temp is 79°F. January and February are the coldest months when the average temperature is 51°F. August and July are the months with the most rain.

Why should I book my Neeses hotel with Hotels.com?

There are lots of reasons to book your Neeses trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.