Hotels in Isla Santa María

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Next weekend
Jul 31 - Aug 2
In two weeks
Aug 7 - Aug 9

Where to stay in Isla Santa María?

Gazebo

Enchanted Galapagos Lodge

Enchanted Galapagos Lodge
3.0 star property
Bella Vista
8.0 out of 10, Very Good, (3 reviews)
The price is $224
$224 total
Jul 26 - Jul 27
Enchanted Galapagos Lodge
Property entrance

Suymar Ecolodge Galapagos

Suymar Ecolodge Galapagos
3.0 star property
Bella Vista
9.2 out of 10, Wonderful, (20 reviews)
Unwind at this peaceful ecolodge with 2 restaurants and bars, plus a relaxing outdoor pool and spa. Free breakfast, WiFi and parking complement your stay, while nearby Fishing Piers and Charles Darwin Research Station await exploration.
The price is $70
$95 total
Jul 27 - Jul 28
Suymar Ecolodge Galapagos
Front of property

Twin Hotel Galapagos

Twin Hotel Galapagos
3.0 star property
Bella Vista
8.6 out of 10, Excellent, (49 reviews)
Escape to a verdant sanctuary with Regional cuisine at Las Gemelas restaurant and refreshing dips in the outdoor pool. Near Charles Darwin Research Station, this Bella Vista gem offers free breakfast, WiFi, and convenient parking.
The price is $61
$61 total
Jul 26 - Jul 27
Twin Hotel Galapagos
Family Suite | Balcony view

Posada del Mar

Posada del Mar
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (258 reviews)
This Puerto Ayora gem combines a safe, central location with proximity to Malecon and Gus Angermeyer Ferry Terminal. Guests consistently praise the helpful team while enjoying convenient daily housekeeping and laundry services during their Galápagos adventure.
The price is $83
$83 total
Jul 28 - Jul 29
Posada del Mar
Living area

HOTEL CROSSMAN

HOTEL CROSSMAN
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
The price is $51
$51 total
Jul 26 - Jul 27
HOTEL CROSSMAN
Standard Triple Room | In-room safe, desk, laptop workspace, iron/ironing board (on request)

Capitan Max B&B

Capitan Max B&B
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (241 reviews)
Wake up to complimentary continental breakfast at this Puerto Ayora retreat near Malecon and Las Ninfas Lagoon. Fellow travelers praise the helpful staff while free WiFi and parking enhance your Galápagos adventure.
The price is $77
$77 total
Jul 26 - Jul 27
Capitan Max B&B
Outdoor pool

Maidith Galapagos Inn

Maidith Galapagos Inn
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (151 reviews)
Immerse yourself in nature at this Puerto Ayora sanctuary with outdoor and children's pools. Just steps from Galápagos National Park, the hotel offers delicious breakfast and helpful staff. Fishing Piers and Gus Angermeyer Ferry Terminal are nearby.
The price is $130
$130 total
Aug 5 - Aug 6
Maidith Galapagos Inn
Free daily cooked-to-order breakfast

Angermeyer Waterfront Inn

Angermeyer Waterfront Inn
3.5 star property
Puerto Ayora
9.4 out of 10, Exceptional, (140 reviews)
The price is $282
$310 total
Aug 8 - Aug 9
Angermeyer Waterfront Inn
Suite Signature | In-room safe, desk, laptop workspace, blackout drapes

Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge
4.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (131 reviews)
Surrounded by natural wonder at this Puerto Ayora waterfront lodge with international dining at Almar by Isla Grill. Explore Galápagos National Park just steps away or visit nearby Charles Darwin Research Station using complimentary bikes.
The price is $215
$237 total
Aug 18 - Aug 19
Blu Galapagos Sustainable Waterfront Lodge
Exterior

White House Galapagos

White House Galapagos
2.5 star property
Puerto Ayora
9.0 out of 10, Wonderful, (106 reviews)
Discover Puerto Ayora's natural wonders from this well-positioned hotel adjacent to Galápagos National Park. Enjoy daily housekeeping, complimentary WiFi, and free parking while exploring nearby Fishing Piers and Las Ninfas Lagoon.
The price is $40
$40 total
Aug 11 - Aug 12
White House Galapagos
Jetted tub

Hotel Fiesta

Hotel Fiesta
3.5 star property
Puerto Ayora
9.0 out of 10, Wonderful, (423 reviews)
Cool off in the outdoor pool or relax in one of 3 hot tubs at this Puerto Ayora retreat. Enjoy drinks at the poolside bar, dine at the on-site restaurant, and explore nearby Las Ninfas Lagoon and Malecon. The attentive staff ensures a memorable Galápagos adventure.
The price is $140
$140 total
Jul 28 - Jul 29
Hotel Fiesta
Outdoor pool

Natura Gardens Galápagos Hotel

Natura Gardens Galápagos Hotel
3.0 star property
Bella Vista
6.0 out of 10, (5 reviews)
Unwind at this Bella Vista retreat offering massages, outdoor pool, and a poolside bar surrounded by lush gardens. Just steps from Galápagos National Park with Charles Darwin Research Station nearby. Daily housekeeping and free breakfast enhance your island adventure.
The price is $209
$209 total
Jul 26 - Jul 27
Natura Gardens Galápagos Hotel
Outdoor pool

Hotel Galapagos Tortuga Bay

Hotel Galapagos Tortuga Bay
2.0 star property
Bella Vista
7.6 out of 10, Good, (5 reviews)
The price is $140
$154 total
Aug 23 - Aug 24
Hotel Galapagos Tortuga Bay
Exterior

Hotel Palace Galapagos

Hotel Palace Galapagos
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (113 reviews)
Just steps from Galápagos National Park, this Puerto Ayora hotel offers free WiFi and a garden. Enjoy nearby hiking trails, scuba diving, and snorkeling adventures. Fishing Piers and Gus Angermeyer Ferry Terminal add to the exploration options.
The price is $81
$81 total
Aug 8 - Aug 9
Hotel Palace Galapagos
Front of property

Lonesome George Ecolodge

Lonesome George Ecolodge
2.5 star property
Puerto Ayora
9.2 out of 10, Wonderful, (27 reviews)
Moments from Puerto Ayora's scenic Fishing Piers, this tranquil ecolodge borders Galápagos National Park. Guests can enjoy hiking trails, kayaking, and mountain biking nearby, plus relax in the garden after adventure-filled days.
The price is $100
$100 total
Jul 26 - Jul 27
Lonesome George Ecolodge
Free daily continental breakfast

Hotel Cucuve

Hotel Cucuve
4.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (297 reviews)
Wake up to complimentary continental breakfast at this welcoming B&B near Fishing Piers and Gus Angermeyer Ferry Terminal. Enjoy snorkeling adventures nearby, relax on the terrace, or grab a bite at the snack bar after exploring the national park.
The price is $220
$242 total
Jul 26 - Jul 27
Hotel Cucuve
Beach nearby, white sand

Hotel Ninfa

Hotel Ninfa
3.5 star property
Puerto Ayora
8.4 out of 10, Very Good, (244 reviews)
This charming hotel in Puerto Ayora features an outdoor pool, hot tub, and onsite massages for post-adventure relaxation. Enjoy the bar and café after exploring nearby Malecon and the ferry terminal for island hopping.
The price is $158
$158 total
Jul 26 - Jul 27
Hotel Ninfa
TV

El Barranco Galapagos

El Barranco Galapagos
2.5 star property
Puerto Ayora
9.8 out of 10, Exceptional, (83 reviews)
Immerse yourself in Puerto Ayora's natural beauty at this Mediterranean hotel with an outdoor pool and hot tub. Steps from Galápagos National Park, enjoy free breakfast and WiFi while exploring nearby Malecon and the ferry terminal.
The price is $223
$223 total
Aug 3 - Aug 4
El Barranco Galapagos
Exterior

Galapagos Verde Azul

Galapagos Verde Azul
3.0 star property
Puerto Ayora
8.6 out of 10, Excellent, (65 reviews)
This beach hotel in Puerto Ayora offers an outdoor pool and convenient access to Galápagos National Park. Enjoy free breakfast, WiFi, and parking while staying near Fishing Piers and the Gus Angermeyer Ferry Terminal.
The price is $89
$89 total
Aug 1 - Aug 2
Galapagos Verde Azul
Outdoor dining

Lava House Hostal

Lava House Hostal
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (54 reviews)
Wake to continental breakfast at this Puerto Ayora hideaway before exploring nearby Galápagos National Park. Hiking, kayaking, and mountain biking enthusiasts will love the location, while the garden terrace offers a peaceful retreat after outdoor adventures.
The price is $111
$111 total
Jul 26 - Jul 27
Lava House Hostal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top landmarks in Isla Santa María

A sea turtle swimming underwater.
Photo by Tove Martin
Open Photo by Tove Martin

Post Office Bay

Post Office Bay is 4 mi (6.4 km) from central Isla Santa María, why not stop by during your stay.
See properties

Learn more about Isla Santa María

Isla Santa María is well-known for its attractions such as Galápagos National Park and Post Office Bay.

See all hotels in Isla Santa María
A beach with sea lions resting on the sand and a cruise ship in the distance.
Photo by Delen Wong
Open Photo by Delen Wong

Check out reviews of Isla Santa María hotels guests love

Hotel Cucuve

Hotel Cucuve

10/10 Excellent
"Clean room. Helpful staff. Great location m."
Natalie 3-night trip
Posted 1 day ago
Hotel Cucuve

Frequently asked questions

Can I book refundable hotels in Isla Santa María?
If you're looking for the flexibility to change your plans to Isla Santa María, most properties provide refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Isla Santa María be like during my trip?
With an average temperature of 72°F, Isla Santa María is a great place if you want to enjoy the sunshine year all year long.
Why should I book my Isla Santa María hotel through Hotels.com?
There are plenty of reasons to book your Isla Santa María travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.