Hotels in Santa Fe

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Harbor House Hotel and Marina at Pier 21
Harbor House Hotel and Marina at Pier 21
3.0 star property
Strand Historic District
9.4 out of 10, Exceptional, (1,959 reviews)
  • cleanliness
    Nautical getaway with stunning harbor views and easy cruise terminal access.
The price is $125
$144 total
includes taxes & fees
Apr 9 - Apr 10
Harbor House Hotel and Marina at Pier 21
Best Western Plus Seawall Inn & Suites By The Beach
Best Western Plus Seawall Inn & Suites By The Beach
2.5 star property
San Marino
8.6 out of 10, Excellent, (1,002 reviews)
  • cleanliness
    Seaside convenience with pool and fitness center, just minutes from cruise terminal.
The price is $80
$92 total
includes taxes & fees
Apr 6 - Apr 7
Best Western Plus Seawall Inn & Suites By The Beach
Studio 6 Houston, TX – Pearland/Medical Center
Studio 6 Houston, TX – Pearland/Medical Center
2.0 star property
Southeast Houston
9.4 out of 10, Exceptional, (25 reviews)
The price is $75
$88 total
includes taxes & fees
Apr 5 - Apr 6
Studio 6 Houston, TX – Pearland/Medical Center
TRU BY Hilton Galveston
TRU BY Hilton Galveston
2.5 star property
Midtown
8.2 out of 10, Very Good, (1,508 reviews)
  • cleanliness
    Modern Galveston retreat with pool near port, cruise terminal, and seawall.
The price is $92
$105 total
includes taxes & fees
Apr 14 - Apr 15
TRU BY Hilton Galveston
Moody Gardens Hotel, Spa and Convention Center
Moody Gardens Hotel, Spa and Convention Center
4.0 star property
Near West End
9.0 out of 10, Wonderful, (2,024 reviews)
  • cleanliness
    Escape to waterfront resort with on-site marina, spa, and tropical gardens.
The price is $169
$194 total
includes taxes & fees
Apr 6 - Apr 7
Moody Gardens Hotel, Spa and Convention Center
Palace Inn Blue Edgebrook
Palace Inn Blue Edgebrook
3.0 star property
Southeast Houston
9.4 out of 10, Exceptional, (163 reviews)
  • cleanliness
    Discover comfortable rooms just 15 minutes from Houston's downtown attractions.
The price is $109
$132 total
includes taxes & fees
Apr 5 - Apr 6
Palace Inn Blue Edgebrook
Home2 Suites by Hilton Texas City Houston
Home2 Suites by Hilton Texas City Houston
3.0 star property
Texas City
8.8 out of 10, Excellent, (1,002 reviews)
  • cleanliness
    Family-friendly hotel with outdoor pool and complimentary breakfast in Texas City.
The price is $84
$95 total
includes taxes & fees
Apr 9 - Apr 10
Home2 Suites by Hilton Texas City Houston
Hampton Inn & Suites Houston/League City
Hampton Inn & Suites Houston/League City
2.5 star property
League City
9.0 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Sleek hotel for NASA explorers with complimentary breakfast and fitness amenities.
The price is $88
$99 total
includes taxes & fees
Apr 12 - Apr 13
Hampton Inn & Suites Houston/League City
SpringHill Suites by Marriott Texas City
SpringHill Suites by Marriott Texas City
3.5 star property
Texas City
9.6 out of 10, Exceptional, (955 reviews)
  • cleanliness
    Walk to popular outlets and splash in the seasonal pool at this Texas City hotel.
The price is $80
$90 total
includes taxes & fees
Apr 13 - Apr 14
SpringHill Suites by Marriott Texas City
SureStay Plus Hotel by Best Western Alvin
SureStay Plus Hotel by Best Western Alvin
2.5 star property
Alvin
8.8 out of 10, Excellent, (546 reviews)
The price is $72
$82 total
includes taxes & fees
Apr 9 - Apr 10
SureStay Plus Hotel by Best Western Alvin
La Quinta Inn & Suites by Wyndham Galveston North at I-45
La Quinta Inn & Suites by Wyndham Galveston North at I-45
3.0 star property
Near West End
8.2 out of 10, Very Good, (1,163 reviews)
  • cleanliness
    Chic Art Deco hotel by Moody Gardens with outdoor pool and complimentary perks.
The price is $71
$82 total
includes taxes & fees
Apr 20 - Apr 21
La Quinta Inn & Suites by Wyndham Galveston North at I-45
Best Western Texas City
Best Western Texas City
2.5 star property
Texas City
7.8 out of 10, Good, (1,003 reviews)
  • cleanliness
    Soak up coastal Texas comfort at a seaside retreat with fitness options for travelers.
The price is $85
$98 total
includes taxes & fees
Apr 5 - Apr 6
Best Western Texas City
Super 8 by Wyndham Houston/NASA
Super 8 by Wyndham Houston/NASA
2.0 star property
Nassau Bay
8.2 out of 10, Very Good, (1,002 reviews)
  • cleanliness
    Just minutes from NASA Johnson Space Center and Space Center Houston.
The price is $56
$66 total
includes taxes & fees
Apr 6 - Apr 7
Super 8 by Wyndham Houston/NASA
Best Western Plus Pearland/Houston Medical Center Hotel
Best Western Plus Pearland/Houston Medical Center Hotel
2.5 star property
Southeast Houston
9.2 out of 10, Wonderful, (197 reviews)
  • cleanliness
    Experience comfort just minutes from NRG Stadium and Medical Center attractions.
The price is $89
$104 total
includes taxes & fees
May 4 - May 5
Best Western Plus Pearland/Houston Medical Center Hotel
Seabreeze Hotel, An Ascend Collection Hotel
Seabreeze Hotel, An Ascend Collection Hotel
2.0 star property
San Jacinto
9.4 out of 10, Exceptional, (431 reviews)
  • cleanliness
    Enjoy walks along Galveston Seawall and Pleasure Pier, steps from hotel grounds.
The price is $94
$110 total
includes taxes & fees
Apr 6 - Apr 7
Seabreeze Hotel, An Ascend Collection Hotel
Holiday Inn Express & Suites Galveston West-Seawall
Holiday Inn Express & Suites Galveston West-Seawall
2.5 star property
Near West End
8.6 out of 10, Excellent, (1,001 reviews)
The price is $97
$112 total
includes taxes & fees
Apr 9 - Apr 10
Holiday Inn Express & Suites Galveston West-Seawall
Residence Inn by Marriott Galveston Island
Residence Inn by Marriott Galveston Island
3.0 star property
Midtown
9.6 out of 10, Exceptional, (772 reviews)
  • cleanliness
    Stylish suites near scenic Galveston Seawall with complimentary breakfast and bar.
The price is $114
$131 total
includes taxes & fees
Apr 20 - Apr 21
Residence Inn by Marriott Galveston Island
Hampton Inn & Suites La Porte
Hampton Inn & Suites La Porte
3.0 star property
La Porte
9.4 out of 10, Exceptional, (627 reviews)
  • cleanliness
    Enjoy Gulf Coast comfort near NASA with an outdoor pool and fitness center.
The price is $92
$107 total
includes taxes & fees
Apr 10 - Apr 11
Hampton Inn & Suites La Porte
Home2 Suites By Hilton Galveston
Home2 Suites By Hilton Galveston
3.0 star property
Midtown
8.8 out of 10, Excellent, (1,322 reviews)
  • cleanliness
    Seaside comfort near Galveston Seawall with outdoor pool and complimentary breakfast.
The price is $107
$123 total
includes taxes & fees
Apr 9 - Apr 10
Home2 Suites By Hilton Galveston
Kemah Boardwalk Inn
Kemah Boardwalk Inn
3.0 star property
Kemah
9.2 out of 10, Wonderful, (1,178 reviews)
  • cleanliness
    Serene waterfront hotel on Kemah Boardwalk with marina access and relaxing pool views.
The price is $169
$191 total
includes taxes & fees
Apr 5 - Apr 6
Kemah Boardwalk Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

What hotels do travelers recommend in Santa Fe?
Can I book refundable hotels in Santa Fe?
If you need the flexibility to change your plans to Santa Fe, most properties offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Santa Fe if I want a vacation rental instead of a traditional hotel?
You'll find 8 vacation homes on our site.
What will the weather in Santa Fe be like during my trip?
The warmest months in Santa Fe are usually August and July with an average temp of 82°F. January and February are the chilliest months when the average temp is 59°F. The rainiest months are September and August.
Why should I book my Santa Fe hotel through Hotels.com?
There are plenty of reasons to book your Santa Fe travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.