Hotels in Cairo

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This weekend
Jul 10 - Jul 12
Next weekend
Jul 17 - Jul 19

Where to stay in Cairo?

Lobby

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (291 reviews)
Set off I-57 in Cairo, this welcoming hotel provides complimentary full breakfast and self parking. Explore nearby Fort Defiance State Park or take a short drive to Ballard Wildlife Management Area while enjoying free WiFi throughout your stay.
The price is $68
$75 total
includes taxes & fees
Jul 18 - Jul 19
Quality Inn Cairo I-57
Basic Double Room | Living area

La Center Motel

La Center Motel
2.0 star property
La Center
7.4 out of 10, Good, (20 reviews)
Escape to this relaxing La Center hotel with complimentary WiFi and parking. Just a 15-minute drive from Ohio River Valley and 16 minutes from Paducah Regional Airport, the convenient location makes exploring the area effortless.
The price is $60
$70 total
includes taxes & fees
Jul 9 - Jul 10
La Center Motel
Exterior

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (419 reviews)
The price is $75
$83 total
includes taxes & fees
Jul 9 - Jul 10
The Riverstone Hotel Charleston-Sikeston
Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (647 reviews)
This Charleston motel offers complimentary WiFi, parking, and on-the-go breakfast daily. Located with convenient interstate access to Cape Girardeau, guests consistently praise the helpful staff. The comfortable accommodations provide a practical base for exploring southeastern Missouri.
The price is $60
$66 total
includes taxes & fees
Jul 12 - Jul 13
Super 8 by Wyndham Charleston/Sikeston East MO
House (2 Bedrooms) | Interior

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is $149
$290 total
includes taxes & fees
Aug 2 - Aug 3
Quiet Country Stay: Modern Home Near Paducah
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit Cairo?

Our prices for hotels in Cairo are cheapest in September
Price trends for hotels in Cairo
Pricing is based on two traveler single night rates
View properties in July
Currently viewing crowd sizes and weather for July.
Typical weather for Cairo
July
High 32°C / low 21°C. Sunny most days.
View properties in July
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July, no crowd data, average high temperature 32 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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August, no crowd data, average high temperature 31 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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September, no crowd data, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 21 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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November, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
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December, no crowd data, average high temperature 9 degrees Celsius, average low temperature 1 degrees Celsius. Partly sunny.
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January, no crowd data, average high temperature 6 degrees Celsius, average low temperature -2 degrees Celsius. Partly sunny.
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February, no crowd data, average high temperature 8 degrees Celsius, average low temperature -1 degrees Celsius. Partly sunny.
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March, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
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April, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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May, no crowd data, average high temperature 25 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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June, no crowd data, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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Monthly weather averages (˚C)

Top landmarks in Cairo

Fort Defiance State Park

7.4/10 (15 reviews)
Fort Defiance State Park is 2.3 mi (3.7 km) from central Cairo, why not stop by during your stay.
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Learn more about Cairo

Cairo is well-known for its attractions such as Mississippi River and Ohio River Valley. The city has something for everyone including sights like Fort Defiance State Park within a small-town setting.

See all hotels in Cairo
A steel bridge with a sunset in the background.

Check out reviews of Cairo hotels guests love

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

8/10 Good
"Wanted to use the pool, but had debris on the bottom and no (0) chairs to sit in."
Robert 2-night trip
Posted 15 hours ago
The Riverstone Hotel Charleston-Sikeston

Frequently asked questions

What accommodations do travelers like in Cairo?
Guests like Quality Inn Cairo I-57 and Eagle Inn Charleston.
Can I book refundable accommodations in Cairo?
If you're looking for the flexibility to change your travel plans to Cairo, most hotels offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where should I stay in Cairo if I'm looking for an affordable accommodation?
Quality Inn Cairo I-57 is an accommodation you might want to consider that'll save you money.
What will the weather in Cairo be like during my trip?
The warmest months in Cairo are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and March.
Why should I book my Cairo accommodation with Hotels.com?
There are plenty of reasons to book your Cairo travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.