Photo by Alice Burghart
Hotels in Cape Girardeau
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Where to stay in Cape Girardeau?
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (469)
9.6/10
Exceptional
(469)
- Riverside location with Marriott quality and nearby national forest access.
The price is $125
$125
$142 total
includes taxes & fees
Jan 11 - Jan 12, 2026
The Riverview
The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (477)
9.4/10
Exceptional
(477)
- Try your luck at the casino and savor American cuisine at this Cape Girardeau hotel.
The price is $96
$96
$109 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1004)
9.6/10
Exceptional
(1004)
- Explore the stunning forest views with free breakfast, indoor pool, and dining options.
The price is $90
$90
$102 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1003)
9.0/10
Wonderful
(1003)
- Perfect location near medical center with helpful staff and peaceful atmosphere.
The price is $70
$70
$79 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (144)
9.4/10
Exceptional
(144)
- Stay near Fort D Historic Site with a free breakfast and indoor pool.
The price is $88
$88
$99 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Rockwood Inn
Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (18)
10/10
Exceptional
(18)
- Charming inn near Show Me Center with free parking and garden amenities.
The price is $150
$150
$170 total
includes taxes & fees
Dec 30 - Dec 31
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
9.4/10
Exceptional
(1000)
- Relaxing indoor pool hotel minutes from Cape Splash and historic Fort D sites.
The price is $91
$91
$103 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1001)
9.4/10
Exceptional
(1001)
- Restful hotel near Cape Splash with indoor pool and complimentary amenities.
The price is $90
$90
$102 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very Good, (886)
8.2/10
Very Good
(886)
The price is $70
$70
$84 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (687)
7.2/10
Good
(687)
- Comfortable retreat near Shawnee National Forest with complimentary perks.
The price is $59
$59
$67 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Town House Inn Cape Giradreau
Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.0 out of 10, (206)
6.0/10
(206)
- Affordable lodging close to Cape Girardeau attractions with convenient amenities.
The price is $55
$55
$64 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (785)
9.6/10
Exceptional
(785)
- Relaxing riverside escape with indoor pool and forest access within 10 minutes.
The price is $106
$106
$119 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Tru By Hilton Cape Girardeau
Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (104)
9.6/10
Exceptional
(104)
- Relax at a modern hotel near Shawnee Forest with a refreshing indoor pool.
The price is $89
$89
$102 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1003)
9.0/10
Wonderful
(1003)
- Quiet retreat minutes from Shawnee National Forest offers peaceful and convenient stay.
The price is $70
$70
$79 total
includes taxes & fees
Jan 1 - Jan 2, 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (677)
9.0/10
Wonderful
(677)
The price is $84
$84
$91 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Town House Inn
Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (426)
7.6/10
Good
(426)
- Comfortable Jackson motel near Litz Park with free parking and helpful staff.
The price is $70
$70
$76 total
includes taxes & fees
Dec 30 - Dec 31
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1003)
9.6/10
Exceptional
(1003)
- Quiet escape near Cape Girardeau with an indoor pool for year-round enjoyment.
The price is $83
$83
$88 total
includes taxes & fees
Dec 29 - Dec 30
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.2 out of 10, Very Good, (740)
8.2/10
Very Good
(740)
- Wake up to river views near Shawnee National Forest and enjoy indoor pool year-round.
The price is $80
$80
$86 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel 7 Inn Anna
Hotel 7 Inn Anna
2.5 star property
Anna
6.6 out of 10, (217)
6.6/10
(217)
- Serene hotel in Anna with indoor and outdoor pools for year-round relaxation.
The price is $90
$90
$104 total
includes taxes & fees
Dec 29 - Dec 30
EC Reed's Mercantile and Hotel
EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (84)
9.6/10
Exceptional
(84)
- Rustic hotel with hiking trails and free perks in the charming town of Marble Hill.
The price is $117
$117
$127 total
includes taxes & fees
Dec 29 - Dec 30
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Budget hotels in Cape Girardeau and vicinity
7.2 out of 10, Good, (687)
7.2/10
Good
(687)
The price is $59
$59
$67 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG2.5 star property
Cape Girardeau
8.2 out of 10, Very Good, (886)
8.2/10
Very Good
(886)
The price is $70
$70
$84 total
includes taxes & fees
Jan 25 - Jan 26, 2026
9.0 out of 10, Wonderful, (1003)
9.0/10
Wonderful
(1003)
The price is $70
$70
$79 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1003)
9.0/10
Wonderful
(1003)
The price is $70
$70
$79 total
includes taxes & fees
Jan 1 - Jan 2, 2026
7.6 out of 10, Good, (426)
7.6/10
Good
(426)
The price is $70
$70
$76 total
includes taxes & fees
Dec 30 - Dec 31
8.2 out of 10, Very Good, (740)
8.2/10
Very Good
(740)
The price is $80
$80
$86 total
includes taxes & fees
Jan 4 - Jan 5, 2026
9.6 out of 10, Exceptional, (1003)
9.6/10
Exceptional
(1003)
The price is $83
$83
$88 total
includes taxes & fees
Dec 29 - Dec 30
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau3.0 star property
Jackson
9.0 out of 10, Wonderful, (677)
9.0/10
Wonderful
(677)
The price is $84
$84
$91 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (144)
9.4/10
Exceptional
(144)
The price is $88
$88
$99 total
includes taxes & fees
Jan 4 - Jan 5, 2026
9.6 out of 10, Exceptional, (104)
9.6/10
Exceptional
(104)
The price is $89
$89
$102 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1004)
9.6/10
Exceptional
(1004)
The price is $90
$90
$102 total
includes taxes & fees
Jan 1 - Jan 2, 2026
9.4 out of 10, Exceptional, (1001)
9.4/10
Exceptional
(1001)
The price is $90
$90
$102 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
9.4/10
Exceptional
(1000)
The price is $91
$91
$103 total
includes taxes & fees
Jan 4 - Jan 5, 2026
9.4 out of 10, Exceptional, (477)
9.4/10
Exceptional
(477)
The price is $96
$96
$109 total
includes taxes & fees
Jan 5 - Jan 6, 2026
9.6 out of 10, Exceptional, (84)
9.6/10
Exceptional
(84)
The price is $117
$117
$127 total
includes taxes & fees
Dec 29 - Dec 30
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (785)
9.6/10
Exceptional
(785)
The price is $106
$106
$119 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (469)
9.6/10
Exceptional
(469)
The price is $125
$125
$142 total
includes taxes & fees
Jan 11 - Jan 12, 2026
10.0 out of 10, Exceptional, (18)
10/10
Exceptional
(18)
The price is $150
$150
$170 total
includes taxes & fees
Dec 30 - Dec 31
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check out pet-friendly hotels in Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1004)
9.6/10
Exceptional
(1004)
The price is $90
$90
$102 total
includes taxes & fees
Jan 1 - Jan 2, 2026
9.6 out of 10, Exceptional, (104)
9.6/10
Exceptional
(104)
The price is $89
$89
$102 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1003)
9.0/10
Wonderful
(1003)
The price is $70
$70
$79 total
includes taxes & fees
Jan 1 - Jan 2, 2026
9.4 out of 10, Exceptional, (1001)
9.4/10
Exceptional
(1001)
The price is $90
$90
$102 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG2.5 star property
Cape Girardeau
8.2 out of 10, Very Good, (886)
8.2/10
Very Good
(886)
The price is $70
$70
$84 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (785)
9.6/10
Exceptional
(785)
The price is $106
$106
$119 total
includes taxes & fees
Jan 4 - Jan 5, 2026
6.0 out of 10, (206)
6.0/10
(206)
The price is $55
$55
$64 total
includes taxes & fees
Jan 4 - Jan 5, 2026
9.0 out of 10, Wonderful, (1003)
9.0/10
Wonderful
(1003)
The price is $70
$70
$79 total
includes taxes & fees
Jan 1 - Jan 2, 2026
You may also like hotels with pools in Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1004)
9.6/10
Exceptional
(1004)
The price is $90
$90
$102 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (144)
9.4/10
Exceptional
(144)
The price is $88
$88
$99 total
includes taxes & fees
Jan 4 - Jan 5, 2026
9.6 out of 10, Exceptional, (104)
9.6/10
Exceptional
(104)
The price is $89
$89
$102 total
includes taxes & fees
Jan 4 - Jan 5, 2026
9.4 out of 10, Exceptional, (1001)
9.4/10
Exceptional
(1001)
The price is $90
$90
$102 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
9.4/10
Exceptional
(1000)
The price is $91
$91
$103 total
includes taxes & fees
Jan 4 - Jan 5, 2026
7.2 out of 10, Good, (687)
7.2/10
Good
(687)
The price is $59
$59
$67 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (785)
9.6/10
Exceptional
(785)
The price is $106
$106
$119 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG2.5 star property
Cape Girardeau
8.2 out of 10, Very Good, (886)
8.2/10
Very Good
(886)
The price is $70
$70
$84 total
includes taxes & fees
Jan 25 - Jan 26, 2026
You can also stay at family-friendly hotels in Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1004)
9.6/10
Exceptional
(1004)
The price is $90
$90
$102 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (144)
9.4/10
Exceptional
(144)
The price is $88
$88
$99 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1003)
9.0/10
Wonderful
(1003)
The price is $70
$70
$79 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG2.5 star property
Cape Girardeau
8.2 out of 10, Very Good, (886)
8.2/10
Very Good
(886)
The price is $70
$70
$84 total
includes taxes & fees
Jan 25 - Jan 26, 2026
9.0 out of 10, Wonderful, (1003)
9.0/10
Wonderful
(1003)
The price is $70
$70
$79 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Cape Girardeau
Pet friendly
Family friendly
When is the best time to visit Cape Girardeau?
When is the best time to visit Cape Girardeau?Our prices for hotels in Cape Girardeau are cheapest in December
When is the best time to visit Cape Girardeau?
When is the best time to visit Cape Girardeau?
Our prices for hotels in Cape Girardeau are cheapest in December
Price trends for hotels in Cape Girardeau
Pricing is based on two traveler single night rates
Currently viewing crowd sizes and weather for December.
Typical weather for Cape Girardeau
December
Low crowds
High 9°C / low 1°C. Partly sunny.
View properties in December 9°
December, Low crowds, average high temperature 9 degrees Celsius, average low temperature 1 degrees Celsius. Partly sunny.
1°
6°
January, Low crowds, average high temperature 6 degrees Celsius, average low temperature -2 degrees Celsius. Partly sunny.
-2°
8°
February, Low crowds, average high temperature 8 degrees Celsius, average low temperature -1 degrees Celsius. Partly sunny.
-1°
14°
March, High crowds, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Sunny most days.
5°
19°
April, High crowds, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
25°
May, High crowds, average high temperature 25 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
15°
30°
June, Moderate crowds, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
32°
July, Moderate crowds, average high temperature 32 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
31°
August, Moderate crowds, average high temperature 31 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
28°
September, Low crowds, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
21°
October, High crowds, average high temperature 21 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
11°
13°
November, Moderate crowds, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Partly sunny.
4°
Monthly weather averages (˚C)
Top landmarks in Cape Girardeau
Cape Splash Family Aquatic Center
Why not give yourself a treat with a trip to Cape Splash Family Aquatic Center, one of the family attractions located 3.1 mi (5.1 km) from central Cape Girardeau. If you have fun at Cape Splash Family Aquatic Center, you'll love Cape Girardeau Conservation Nature Center and Lazy L Safari Park, both located nearby.
Cape Girardeau Conservation Nature Center
4.6/5 (27 reviews)
Cape Girardeau Conservation Nature Center is 4.8 mi (7.8 km) from central Cape Girardeau, why not stop by during your stay. If you have fun at Cape Girardeau Conservation Nature Center, you'll love Cape Splash Family Aquatic Center and Lazy L Safari Park, both located nearby.
Learn more about Cape Girardeau
Hugging the Mississippi River, this college town reveals its history through vibrant floodwall murals that transform concrete into an outdoor gallery. Southeast Missouri State University brings youthful energy to streets lined with locally-owned shops and cafes. The River Campus hosts performances in a former seminary with river views. Explore the Cape Girardeau Conservation Nature Center or paddle the Mississippi. Trail of Tears State Park offers hiking paths with panoramic vistas that explain why settlers chose this dramatic spot. The Cape Riverfront Market buzzes with farmers and artisans, while the historic downtown invites exploration with red-brick buildings housing quirky boutiques and restaurants serving hearty Midwestern fare with surprising sophistication.
Photo by Alice Burghart
Open Photo by Alice Burghart
Check out reviews of Cape Girardeau hotels guests love
Tru By Hilton Cape Girardeau
10/10 Excellent
"They were great "
Pear Tree Inn Cape Girardeau Near the Medical Center
10/10 Excellent
"Everything was wonderful. Staff (especially Debbie) was the best. This is a nice quiet comfortable pplace to stay"
Fairfield Inn & Suites by Marriott Cape Girardeau
10/10 Excellent
"Spacious clean rooms. Great location. Friendly staff."
Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
"The room was great. Very clean and the bed was comfortable. "
Pear Tree Inn Cape Girardeau West
10/10 Excellent
"Breakfast great hot and big variety "
Quality Inn
10/10 Excellent
"Comfortable bed"
Candlewood Suites Cape Girardeau by IHG
10/10 Excellent
"Room was clean and spacious."
Hampton Inn Cape Girardeau I 55 East
10/10 Excellent
"Cleanliest hotel I’ve ever stayed at! Staff was friendly. Room was spacious. Bed was comfortable. I would 100% recommend! Close to the university. Across the street from Starbucks and many other places to eat."
The Riverview
10/10 Excellent
"The room was clean and the mattress was extremely comfortable "
Frequently asked questions
What hotels do travelers recommend in Cape Girardeau?
Rockwood Inn, Fairfield Inn & Suites by Marriott Cape Girardeau and Tru By Hilton Cape Girardeau are all properties that our guests really like.
Can I book a refundable hotel in Cape Girardeau?
If you need the flexibility to change your travel plans to Cape Girardeau, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Cape Girardeau if I'm looking for an affordable accommodation?
Pear Tree Inn Cape Girardeau Near the Medical Center, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG and Candlewood Suites Cape Girardeau by IHG are a few accommodations you might want to consider that'll save you money.
Where can I stay in Cape Girardeau if I want a vacation rental instead of a hotel?
If you want a good alternative to a hotel, look over our selection of 22 vacation homes. In addition, you can choose from 16 apartments.
What will the weather in Cape Girardeau be like during my vacation?
July and August are typically the warmest months in Cape Girardeau when the average temp is 76°F. January and February are the coldest months when the average temperature is 40°F. April and March are the months with the most rain.
Why should I book my Cape Girardeau hotel through Hotels.com?
There are lots of reasons to book your Cape Girardeau trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.