Hotels in Charleston
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Tonight
Sep 12 - Sep 13Tomorrow
Sep 13 - Sep 14Next weekend
Sep 18 - Sep 20In two weeks
Sep 25 - Sep 27Where to stay in Charleston?
1. The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
$66
$74 total
includes taxes & fees
Sep 14 - Sep 15
2. Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
$60
$66 total
includes taxes & fees
Sep 13 - Sep 14
3. Eagle Inn Charleston
Eagle Inn CharlestonCharleston
$77
$85 total
includes taxes & fees
Sep 13 - Sep 14
4. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
$102
$117 total
includes taxes & fees
Sep 17 - Sep 18
5. Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
$87
$99 total
includes taxes & fees
Sep 13 - Sep 14
6. Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
$98
$111 total
includes taxes & fees
Oct 11 - Oct 12
7. Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
$70
$78 total
includes taxes & fees
Oct 2 - Oct 3
8. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
$101
$114 total
includes taxes & fees
Sep 20 - Sep 21
9. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
$69
$79 total
includes taxes & fees
Sep 13 - Sep 14
10. Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
$66
$76 total
includes taxes & fees
Sep 15 - Sep 16
11. La Center Motel
La Center MotelLa Center
$54
$63 total
includes taxes & fees
Sep 20 - Sep 21
12. Hampton Inn Sikeston
Hampton Inn SikestonSikeston
$102
$115 total
includes taxes & fees
Oct 11 - Oct 12
13. Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55Sikeston
$89
$101 total
includes taxes & fees
Oct 4 - Oct 5
14. Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner AreaSikeston
$57
$65 total
includes taxes & fees
Sep 20 - Sep 21
15. Quiet Country Stay: Modern Home Near Paducah
Quiet Country Stay: Modern Home Near PaducahCunningham
$149
$290 total
includes taxes & fees
Sep 28 - Sep 29
16. Country Yard Inn and Suite
Country Yard Inn and SuiteSikeston
$59
$71 total
includes taxes & fees
Sep 16 - Sep 17
17. TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
$109
$123 total
includes taxes & fees
Oct 11 - Oct 12
18. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
$100
$113 total
includes taxes & fees
Sep 17 - Sep 18
19. The Riverview
The RiverviewCape Girardeau
$114
$129 total
includes taxes & fees
Sep 14 - Sep 15
20. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
$72
$81 total
includes taxes & fees
Sep 20 - Sep 21
Go beyond your typical stay in Charleston
Pet friendly
Family friendly
Our prices for hotels in Charleston are cheapest in January
Our prices for hotels in Charleston are cheapest in January
Price trends for hotels in Charleston
Pricing is based on two traveler single night rates
Learn more about Charleston
Charleston is well-known for its attractions such as Mississippi River and Ohio River. Visitors give high marks to the city's restaurants and small-town setting.
See all hotels in Charleston
Check out reviews of Charleston hotels guests love
Drury Inn & Suites Cape Girardeau
10/10 Excellent
"Excellent full breakfast."
Pear Tree Inn Cape Girardeau West
10/10 Excellent
"The nicest staff! Even the housekeeping staff, who were just walking in to start their shift and hadn’t even clocked in gave me a genuine “Good morning” and a smile. I love these people!"
The Riverview
10/10 Excellent
"I can’t rave enough about this hotel. 5 ♥️s. It takes zero effort to be kind. The staff is kind and helpful. Highly recommend to anyone staying in Cape Girardeau, MO. This hotel rises above the chain hotels 🏨."
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
10/10 Excellent
"Excellent breakfast,friendly staff and clean rooms"
Fairfield Inn & Suites by Marriott Cape Girardeau
10/10 Excellent
"The receptionist was very courteous. Helped answer all my questions. We loved the room. And we had a great breakfast before we left."
Super 8 by Wyndham Sikeston/Miner Area
10/10 Excellent
"We had no problem checking in. The room was nice and clean. The staff were courteous and helpful. Parking was acceptable. Close to our room. No complaints."
Hampton Inn Sikeston
10/10 Excellent
"Really quiet place close to good restaurants and stores."
The Riverstone Hotel Charleston-Sikeston
10/10 Excellent
"Everything was fine for a one night stay."
Best Western Plus Sikeston I-55
8/10 Good
"Great location, nice, clean and well maintained, Hotel employees were very helpful great customer service,"