An aerial view of a town with industrial buildings, roads, and green areas.

Hotels in St. Charles

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Where to stay in St. Charles?

A hotel room with a large bed, a separate bathroom with a bathtub, a desk with a chair, and a large mirror.

A multi-story hotel with a prominent "American" sign, a parking lot with several cars, and a landscaped entrance area.

A hotel room with a sofa, a small table, a TV, a microwave, and a door.

A hotel lobby with seating, a fireplace, a clock, and a reception area.

1. AmericInn by Wyndham Winona

Winona

$118

$132 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with two beds, a large landscape painting above the headboard, a bedside table with a phone, and a blue patterned rug.

A breakfast area with a coffee station, a refrigerator, and a dining table with chairs.

A reception area with a counter, a clock, a desk with a computer, and a framed picture on the wall.

A modern room with two sofas, a coffee table, and large windows with curtains.

2. Days Inn by Wyndham Winona

Winona

$68

$76 total

includes taxes & fees

Nov 1 - Nov 2

A two-story house with a porch and a covered entryway.

A bedroom with a wooden wardrobe, a bedside table with a lamp, and a bed with white bedding and a red pillow.

A porch with a white door labeled "WENNESON" and a welcome wreath.

A room with two patterned sofas, a small table with a lamp, and a window with curtains.

3. The Wen Inn formerly Andor Wenneson

Peterson

$105

$114 total

includes taxes & fees

Oct 7 - Oct 8

A cozy living room with a fireplace, a sofa, a coffee table, and a view through large windows.

A dining room with a long wooden table set for a meal, surrounded by chairs.

A white two-story house with green shutters, a porch, and a sign that reads "Bed & Breakfast."

A garden with a pergola, a wooden table, and a variety of plants.

4. Carriage House B&B

Historic Downtown Winona

$124

$138 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with two beds, a desk with a chair, a TV, and a large waterfall painting on the wall.

A breakfast area with a wooden wall, a clock, and a coffee machine.

An outdoor patio with a table and chairs, a red umbrella, and a view of trees and a sunset.

A hotel room with large windows, a clock, and framed pictures on the walls.

5. Super 8 by Wyndham Winona MN

Winona

$57

$64 total

includes taxes & fees

Nov 1 - Nov 2

A table set for a meal with various dishes, glasses of orange juice, and a vase with flowers.

A room with a portrait framed in gold, red curtains, and a table with ornate candle holders.

A grand staircase with a floral carpet, wooden balustrades, and a chandelier.

A spacious room with wooden paneling, a chandelier, a fireplace, and a large rug.

6. Alexander Mansion Bed and Breakfast

Historic Downtown Winona

$119

$133 total

includes taxes & fees

Nov 1 - Nov 2

A display of ceramic mugs and bowls on a table with a white tablecloth, illuminated by string lights.

A cozy room with a red patterned armchair, a matching sofa, and a glass coffee table with magazines. A lamp and air conditioner are visible, along with a table displaying various items in the background.

A spacious room with a high ceiling, wooden beams, and a large window displaying a sign for The Rushford Inn.

A kitchen with wooden cabinets, a granite countertop, and a built-in microwave.

7. The Rushford Inn

Rushford

$159

$171 total

includes taxes & fees

Oct 6 - Oct 7

A hotel pool area with multiple lounge chairs, a pool, and a second-floor balcony with windows.

A brick building with a sign reading "Riverport Inn & Suites" and two flags.

A bar area with wooden bar stools, a counter, and a menu board.

A spacious lobby with a stone fireplace, leather seating, a staircase with glass railings, and a view of the outside through large windows.

8. Express Suites Riverport Inn & Suites

Winona

$120

$134 total

includes taxes & fees

Oct 6 - Oct 7

An outdoor seating area with wicker chairs and tables, surrounded by vibrant flowers and a red umbrella.

A cozy living room with a fireplace, a staircase, and a dining area.

A spacious living area with a high ceiling, wooden beams, a blue armchair, a sofa, and a glass coffee table.

A bedroom with a large bed, a bathtub, a wooden rocking chair, and a desk with a lamp.

9. Stone Mill Hotel & Suites

Lanesboro

$105

$113 total

includes taxes & fees

Oct 18 - Oct 19

A multi-story building with a balcony, surrounded by various potted plants and flowers.

A bedroom with a four-poster bed, a sitting area with a sofa, a small table with a vase, and a bathtub.

A porch with a variety of potted plants and flowers, a sign reading "OFFICE Welcome to Green Gables," and a door with a green doorbell.

An outdoor patio with tables and chairs, green umbrellas, and a wooden deck.

10. Green Gables Inn

Lanesboro

$94

$101 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel lobby with a dining area, seating arrangements, and a stone fireplace.

An outdoor patio area with stone walls, a stone fireplace, and multiple tables and chairs.

A hotel with a modern design, featuring a stone facade and a covered entrance.

An indoor swimming pool with clear glass walls, a tiled floor, and a few chairs around the pool area.

11. Fairfield Inn & Suites by Marriott Winona

Winona

$134

$150 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor seating area with brick walls, green railings, and hanging flower baskets.

A hotel with a central clock tower, multiple windows, and a parking lot with cars.

A bar area with wooden chairs and tables, a bar counter with bottles and glasses, and a television screen displaying a sports game.

A pool with a large, colorful fish-shaped slide.

12. The Plaza Hotel & Suites Winona

Winona

$145

$162 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a blue sofa, a wooden coffee table, a lamp, a TV, and a door leading to a balcony.

13. Holiday Inn Express & Suites Winona by IHG

Winona

$161

$180 total

includes taxes & fees

Nov 2 - Nov 3

A hotel room with two beds, a desk, a chair, and a lamp.

A lobby with a checkered floor, two blue armchairs, a table with a lamp, and a 'WELCOME' sign.

A hotel lobby with a dining area, a fireplace, and a television displaying a map.

A living room with a brick fireplace, two armchairs with decorative pillows, and a framed map on the wall.

14. Country Trails Inn & Suites

Preston

$126

$140 total

includes taxes & fees

Oct 6 - Oct 7

A hotel room with a large bed, a desk with a chair, a window with a view of the outdoors, and two bedside lamps.

A modern living room with a sofa, two armchairs, a coffee table, and a large window offering a view of the outdoors.

A gym with treadmills, elliptical machines, and a stationary bike.

A reception desk with a wooden finish, a large illuminated 'C' sign, and a modern light fixture on the ceiling.

15. Comfort Inn & Suites Rochester South Mayo Clinic

Rochester

$86

$100 total

includes taxes & fees

Oct 10 - Oct 11

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

A reception area with a wooden reception desk, a red doormat, and framed awards on the wall.

A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.

A hotel room with a large bed, a desk, a chair, a television, and a window with curtains.

16. Econo Lodge Mayo Clinic Area

Rochester

$70

$81 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel lobby with a reception desk, seating area, and a kitchenette.

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

A hotel room with a large bed, a desk, a chair, and a kitchenette.

A small, well-organized pantry with shelves stocked with snacks and beverages.

17. Spark by Hilton Rochester South

Rochester

$87

$100 total

includes taxes & fees

Nov 1 - Nov 2

A La Quinta Inn & Suites hotel with a well-lit entrance, a parking area, and a clear view of the building's facade.

A buffet counter with a variety of food items, a coffee station, and a beverage dispenser.

A modern lobby with a teal sofa, yellow chairs, a small round table, and a fireplace with a TV.

An indoor swimming pool with a slide, seating areas, and a lifeguard station.

18. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

Rochester

$71

$82 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with a large bed, a television, a desk, and a window with curtains.

A modern kitchen with a coffee machine, a refrigerator, and a window with a view. There are tables and chairs arranged for dining.

A compact kitchen with a refrigerator, microwave, and sink. There's a small dining table with a chair.

A lobby with two leather armchairs, a welcome sign, and a lamp on a small table.

19. MainStay Suites Rochester South Mayo Clinic

Rochester

$61

$70 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with a large bed, a desk with a chair, a television, and a view of the outdoors through a door.

A hotel room with a large bed, a desk, a chair, and a TV.

A breakfast corner with a counter, seating area, and a red partition.

An indoor swimming pool with clear blue water, a ladder, and blue chairs around the pool.

20. Baymont by Wyndham Rochester Mayo Clinic Area

Rochester

$60

$69 total

includes taxes & fees

Oct 25 - Oct 26

View all properties

Go beyond your typical stay in St. Charles

Learn more about St. Charles

St. Charles is well-known for its attractions such as Whitewater State Park and Whitewater River.

See all hotels in St. Charles

Check out reviews of St. Charles hotels guests love

Alexander Mansion Bed and Breakfast

Historic Downtown Winona

10/10 Exceptional

We stayed in the Alexander Suite, which was ideal for us. King size bed, Victorian charm, tidy bathroom with tub, shower and amenities. Enjoyed the Watkins lotion. The room has an adjacent sitting room perfect for coffee, tea, or relaxing. Don't forget to write something in the journal. The host, Richard, is super nice and so knowledgeable about the area. The huge breakfast consists of 5 courses. Fruit parfait, fresh baked bread that is to die for. The blueberry was our favorite. The main...

Laila and David

Carriage House B&B

Historic Downtown Winona

10/10 Exceptional

Anonymous traveler

Green Gables Inn

Lanesboro

10/10 Exceptional

RICHARD

Fairfield Inn & Suites by Marriott Winona

Winona

10/10 Exceptional

Ginger

Super 8 by Wyndham Winona MN

Winona

10/10 Exceptional

Ernesto

Holiday Inn Express & Suites Winona by IHG

Winona

10/10 Exceptional

Tyler

Days Inn by Wyndham Winona

Winona

10/10 Exceptional

Jeanine

The Plaza Hotel & Suites Winona

Winona

10/10 Exceptional

Tim

The Rushford Inn

Rushford

10/10 Exceptional

Bonnie

The Wen Inn formerly Andor Wenneson

Peterson

10/10 Exceptional

Marcia

Country Trails Inn & Suites

Preston

10/10 Exceptional

Jean

Stone Mill Hotel & Suites

Lanesboro

10/10 Exceptional

Michael

A modern hotel lobby with a reception desk, seating area, and a dining space.

A modern hotel room with a wooden desk, orange chair, dark sofa, and a small table.

A modern breakfast area with a counter displaying various food items, a water dispenser, and a sign indicating a bakery section.

A Holiday Inn Express building with a stone facade and illuminated signage.

Holiday Inn Express Rochester South - Mayo Area by IHG

Rochester

10/10 Exceptional

Craig

A spacious outdoor dining area with modern furniture and large windows offering views of the city.

A modern interior with a wooden ceiling, a large black shelving unit, and a refrigerator stocked with beverages.

A reception desk with a modern design, featuring a wooden panel and a wall adorned with framed botanical artwork.

An outdoor dining area with wooden beams, tables, and chairs.

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester

10/10 Exceptional

Jay

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

A modern lounge area with a sofa, chairs, and tables.

A modern restaurant with a counter, seating area, and a TV screen.

A modern hotel room with a bed, desk, and kitchenette.

Home2 Suites by Hilton Rochester Mayo Clinic Area

Rochester

10/10 Exceptional

Mary

A modern indoor patio with a fire feature, seating, and large windows.

A modern interior with a seating area, a bookshelf, and a window with a view of trees.

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park

10/10 Exceptional

ryan

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

A hotel lobby with a patterned carpet, two beige armchairs, a small table, a clock, a fire extinguisher, and a staircase.

A hotel room with a large bed, bedside tables, a mirror, and a patterned carpet.

A compact kitchen with a microwave, refrigerator, and coffee maker. A small bar stool is near the counter.

Quality Inn & Suites Mayo Clinic Area

Rochester

10/10 Exceptional

Beth

A coffee shop interior with a wooden counter, menu boards, and seating area.

A hotel exterior with a 'Townplace Suites' sign, outdoor seating area, and 'OPEN' signage.

An outdoor seating area with tables and chairs, a neon sign, and flower arrangements.

A hotel room with a bed, bedside table, and a window with curtains.

TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park

10/10 Exceptional

Neil

Frequently Asked Questions

What accommodations do travelers recommend in St. Charles?

White Valley Motel is an accommodation that is popular with guests.

Can I book refundable accommodations in St. Charles?

If you need the flexibility to change your plans to St. Charles, most properties provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in St. Charles be like during my vacation?

July and August are typically the warmest months in St. Charles when the average temp is 67°F. January and February are the coldest months when the average temperature is 22°F. June and May are the months with the most rain.

Why should I book my St. Charles accommodation with Hotels.com?

There are plenty of reasons to book your St. Charles travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.