Resorts and Hotels with Spas in St. Louis

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Aug 9 - Aug 10
Tomorrow
Aug 10 - Aug 11
Next weekend
Aug 14 - Aug 16
In two weeks
Aug 21 - Aug 23

Top 5 Resorts and Hotels with Spas in St. Louis at a glance

  1. 21C Museum Hotel St Louis — 4.5-star hotel in Downtown West. Guest rating: 9.0/10 — Wonderful.
  2. Four Seasons Hotel St Louis — 5-star hotel in Downtown St. Louis. Guest rating: 9.4/10 — Exceptional.
  3. The Ritz-Carlton, St. Louis — 5-star hotel in Clayton. Guest rating: 9.2/10 — Wonderful.
  4. Truitt Hotel — 2-star hotel in Lafayette Square.
  5. Ameristar Casino Resort and Spa — 4.5-star hotel in St. Charles. Guest rating: 8.6/10 — Excellent.

Resorts and Hotels with Spas in St. Louis

21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Massages
  • Steam room
$144
$173 total
includes taxes & fees
Sep 6 - Sep 7
21C Museum Hotel St Louis

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Full-service spa
  • Massages
  • Steam room
  • Sauna
$375
$438 total
includes taxes & fees
Aug 13 - Aug 14
Four Seasons Hotel St Louis

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Massages
$639
$746 total
includes taxes & fees
Aug 10 - Aug 11
The Ritz-Carlton, St. Louis

Truitt Hotel

Truitt Hotel
Lafayette Square
  • Massages
$188
$227 total
includes taxes & fees
Aug 10 - Aug 11
Truitt Hotel

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Full-service spa
  • Massages
  • Outdoor pool
$156
$199 total
includes taxes & fees
Aug 10 - Aug 11
Ameristar Casino Resort and Spa
See more properties

Discover your perfect spa hotel in St. Louis

Pool
Hot tub
Breakfast included
Gym
5 stars

Top neighborhoods in St. Louis

Downtown St. Louis

Downtown St. Louis serves up major attractions with a side of Midwest charm. The gleaming Gateway Arch watches over historic red-brick buildings, while baseball fans stream toward Busch Stadium on game days. Museum lovers can dive into exhibits at the National Blues Museum, and history buffs will appreciate the limestone Old Courthouse. The neighborhood transforms when Cardinals fans flood the streets, creating an electric atmosphere you can't help but join. Restaurants range from quick lunch spots to upscale steakhouses, with something for every budget. Three convenient MetroLink stations make getting around a breeze, connecting you to the airport and beyond. Hotels cater mainly to business travelers but offer comfortable bases for exploring this walkable downtown core.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Soulard

Historic Soulard charms visitors with cobblestone streets and red brick buildings dating back to the 19th century. The neighborhood buzzes around Soulard Farmers Market, one of America's oldest continuous public markets operating since 1779. St. Louis's French heritage shines through local architecture while the area hosts the country's second-largest Mardi Gras celebration outside New Orleans. Creole-influenced cuisine dominates the food scene, from casual taverns to upscale bistros serving gumbo and po'boys. Boutique inns and historic bed & breakfasts in converted 19th-century homes offer character-filled accommodations. The compact layout makes Soulard perfect for walking, with the Mississippi River waterfront accessible nearby.

The Grove

The Grove pulses with energy as St. Louis's premier LGBTQ+ friendly district. Rainbow crosswalks guide you between craft cocktail lounges, live music venues, and eclectic shops housed in colorful storefronts. Murals wrap around converted warehouses that host everything from late-night dance parties to drag performances, while vintage boutiques and record stores offer daytime browsing. The neighborhood serves up an appetizing mix of gastropubs, late-night diners, and cocktail spots with creative American fusion. MetroLink and bus routes connect you easily to downtown, though most visitors enjoy exploring the compact district on foot. Peak nightlife runs Thursday through Saturday when the streets come alive with celebration and community spirit.

Lafayette Square

Lafayette Square charms with its impressive Victorian mansions and French Second Empire architecture along tree-canopied streets. The neighborhood surrounds the historic 30-acre Lafayette Park, St. Louis' oldest public park, featuring walking paths, a picturesque bandstand, and summer concerts. Architecture enthusiasts will appreciate the ornate ironwork, mansard roofs, and bay windows that transform this area into an outdoor architectural museum. Intimate bistros and cafes serve American comfort food throughout this quiet residential haven. Charming bed-and-breakfasts in restored Victorian homes provide cozy accommodations with period furnishings. The neighborhood is highly walkable with abundant street parking for exploring beyond its peaceful boundaries.

Top landmarks in St. Louis

A baseball stadium with a large crowd, a prominent arch structure, and various advertisements.
Photo by Carl Guttovz

Busch Stadium

9.4/10 (4,850 reviews)
Why not catch an event at Busch Stadium, a major stadium in Downtown St. Louis. Our travelers also like the art galleries and museums in the area. If you think Busch Stadium is cool, you also might like Dome at America’s Center and Enterprise Center, both located nearby.
See properties
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Gateway Arch

9.2/10 (9,046 reviews)
If you're planning a bit of sightseeing head to Gateway Arch— just one of the monuments in Downtown St. Louis. Why not live the cultural experience and visit the museums and art galleries in the area— your sightseeing tour starts here. St. Louis has other landmarks you might want to visit such as St. Louis Union Station.
See properties
A bronze elephant sculpture with a pumpkin on its back, surrounded by greenery.
Photo by Jeff White

St. Louis Zoo

9.2/10 (4,367 reviews)
It's feeding time at the zoo! If you can't resist those cuddly critters you might want to pay a trip to St. Louis Zoo, located 5 mi (8 km) from central St. Louis. Our travelers also like the art galleries and museums in the area. If you have fun at St. Louis Zoo, you'll love Turtle Playground, just a short walk away.
See properties
A cityscape with a prominent statue in the center, surrounded by various buildings and a large stadium.

Enterprise Center

8.8/10 (1,597 reviews)
Imagine soaking up the atmosphere at Enterprise Center, a stadium in Downtown West. Our travelers also like the art galleries and museums in the area. If you think Enterprise Center is cool, you also might like Dome at America’s Center and Busch Stadium, both located nearby.
See properties
A cityscape with a prominent arch structure, various high-rise buildings, and a large government building.

Dome at America’s Center

8.4/10 (1,229 reviews)
Why not catch an event at Dome at America’s Center, a major stadium in Downtown St. Louis. Our travelers also like the art galleries and museums in the area. If you think Dome at America’s Center is cool, you also might like Busch Stadium and Enterprise Center, both located nearby.
See properties
A modern building with large glass windows, surrounded by a garden with red and pink tulips and purple flowers.

Forest Park

9.2/10 (3,389 reviews)
Forest Park is worth a visit, located 4.4 mi (7 km) from central St. Louis. It's also full of great shops and restaurants, so you can spend the afternoon having a wander.
See properties
A tightrope walker balancing on a wire between buildings.

City Museum

9.0/10 (3,209 reviews)
If museums are on your list, you might want to check out the upcoming exhibitions at City Museum in Downtown West. Our travelers also like the art galleries in the area— your cultural tour starts here. If you want to see more of the museums in St. Louis, you can easily walk to Campbell House Museum or Soldiers Memorial Museum.
See properties

America's Center Convention Complex

8.8/10 (306 reviews)
America's Center Convention Complex is worth a pic or two when discovering Downtown St. Louis. Our travelers also like the art galleries and museums in the area.
See properties

Keep exploring