Hotels in Santa Cruz
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in Santa Cruz?
Hotel Finca Las Hortensias
Hotel Finca Las Hortensias
3.0 star property
Tepotzotlán
8.4 out of 10, Very Good, (185)
8.4/10
Very Good
(185)
The price is $60
$60
$72 total
includes taxes & fees
Dec 30 - Dec 31
La Morada Tepotzotlan Boutique & Spa
La Morada Tepotzotlan Boutique & Spa
3.5 star property
Tepotzotlán
8.0 out of 10, Very Good, (40)
8.0/10
Very Good
(40)
Hotel MX mas cuautitlan Izcalli, Trademark by Wyndham
Hotel MX mas cuautitlan Izcalli, Trademark by Wyndham
3.5 star property
Cuautitlan Izcalli
9.2 out of 10, Wonderful, (612)
9.2/10
Wonderful
(612)
The price is $55
$55
$66 total
includes taxes & fees
Dec 30 - Dec 31
Fiesta Inn Cuautitlan
Fiesta Inn Cuautitlan
3.5 star property
Cuautitlan Izcalli
8.6 out of 10, Excellent, (376)
8.6/10
Excellent
(376)
The price is $85
$85
$102 total
includes taxes & fees
Dec 30 - Dec 31
City Express by Marriott Tepotzotlan
City Express by Marriott Tepotzotlan
3.5 star property
Tepotzotlán
8.6 out of 10, Excellent, (734)
8.6/10
Excellent
(734)
The price is $61
$61
$73 total
includes taxes & fees
Jan 4 - Jan 5, 2026
One Cuautitlan
One Cuautitlan
3.0 star property
Cuautitlan Izcalli
8.8 out of 10, Excellent, (541)
8.8/10
Excellent
(541)
The price is $55
$55
$66 total
includes taxes & fees
Dec 30 - Dec 31
Fiesta Inn Express Perinorte
Fiesta Inn Express Perinorte
3.5 star property
Tultitlan
9.0 out of 10, Wonderful, (465)
9.0/10
Wonderful
(465)
The price is $74
$74
$89 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Ramada by Wyndham Ciudad de Mexico Perinorte
Ramada by Wyndham Ciudad de Mexico Perinorte
3.5 star property
Tlalnepantla de Baz
8.4 out of 10, Very Good, (333)
8.4/10
Very Good
(333)
The price is $57
$57
$68 total
includes taxes & fees
Dec 30 - Dec 31
ibis Mexico Perinorte
ibis Mexico Perinorte
3.0 star property
Cuautitlan Izcalli
8.2 out of 10, Very Good, (1003)
8.2/10
Very Good
(1003)
The price is $45
$45
$54 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Antigua Hotel Boutique
Antigua Hotel Boutique
3.5 star property
Ciudad López Mateos
9.2 out of 10, Wonderful, (100)
9.2/10
Wonderful
(100)
The price is $63
$63
$75 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Real Inn Perinorte
Real Inn Perinorte
4.0 star property
Tlalnepantla de Baz
8.6 out of 10, Excellent, (1001)
8.6/10
Excellent
(1001)
The price is $63
$63
$76 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Fiesta Americana México Satélite
Fiesta Americana México Satélite
4.5 star property
Tlalnepantla de Baz
9.4 out of 10, Exceptional, (768)
9.4/10
Exceptional
(768)
The price is $105
$105
$126 total
includes taxes & fees
Dec 30 - Dec 31
NH Mexico City Valle Dorado
NH Mexico City Valle Dorado
4.0 star property
Valle Dorado
8.6 out of 10, Excellent, (975)
8.6/10
Excellent
(975)
The price is $57
$57
$69 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Hotel Madeira
Hotel Madeira
3.5 star property
Ciudad López Mateos
8.6 out of 10, Excellent, (190)
8.6/10
Excellent
(190)
The price is $44
$44
$53 total
includes taxes & fees
Dec 30 - Dec 31
Autoparador del Valle
Autoparador del Valle
3.0 star property
Tlalnepantla de Baz
7.6 out of 10, Good, (19)
7.6/10
Good
(19)
The price is $30
$30
$36 total
includes taxes & fees
Dec 30 - Dec 31
Crowne Plaza Mexico City North-Tlalnepantla by IHG
Crowne Plaza Mexico City North-Tlalnepantla by IHG
4.0 star property
Tlalnepantla de Baz
8.8 out of 10, Excellent, (263)
8.8/10
Excellent
(263)
The price is $91
$91
$109 total
includes taxes & fees
Dec 30 - Dec 31
Fiesta Inn Tlalnepantla
Fiesta Inn Tlalnepantla
3.5 star property
Tlalnepantla de Baz
8.8 out of 10, Excellent, (553)
8.8/10
Excellent
(553)
The price is $75
$75
$90 total
includes taxes & fees
Dec 30 - Dec 31
ibis Mexico Tlalnepantla
ibis Mexico Tlalnepantla
3.0 star property
Tlalnepantla Centro
8.6 out of 10, Excellent, (1037)
8.6/10
Excellent
(1037)
The price is $50
$50
$60 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Krystal Satélite María Bárbara
Krystal Satélite María Bárbara
3.5 star property
Tlalnepantla de Baz
8.4 out of 10, Very Good, (1364)
8.4/10
Very Good
(1364)
The price is $69
$69
$82 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Hotel Parque Satelite
Hotel Parque Satelite
3.0 star property
Tlalnepantla de Baz
9.2 out of 10, Wonderful, (1009)
9.2/10
Wonderful
(1009)
The price is $50
$50
$60 total
includes taxes & fees
Dec 30 - Dec 31
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Budget hotels in Santa Cruz and vicinity
8.2 out of 10, Very Good, (346)
8.2/10
Very Good
(346)
The price is $17
$17
$20 total
includes taxes & fees
Dec 30 - Dec 31
9.0 out of 10, Wonderful, (78)
9.0/10
Wonderful
(78)
Hotel Tres Colonias - Adults Only
Hotel Tres Colonias - Adults Only2.5 star property
Downtown Mexico City
8.0 out of 10, Very Good, (276)
8.0/10
Very Good
(276)
The price is $22
$22
$26 total
includes taxes & fees
Jan 4 - Jan 5, 2026
8.4 out of 10, Very Good, (1007)
8.4/10
Very Good
(1007)
The price is $23
$23
$27 total
includes taxes & fees
Dec 30 - Dec 31
7.6 out of 10, Good, (239)
7.6/10
Good
(239)
8.2 out of 10, Very Good, (526)
8.2/10
Very Good
(526)
The price is $34
$34
$40 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hotel Aquario CDMX - Central del Norte
Hotel Aquario CDMX - Central del Norte3.0 star property
Gustavo A. Madero
7.0 out of 10, Good, (53)
7.0/10
Good
(53)
7.6 out of 10, Good, (19)
7.6/10
Good
(19)
The price is $30
$30
$36 total
includes taxes & fees
Dec 30 - Dec 31
7.2 out of 10, Good, (270)
7.2/10
Good
(270)
The price is $30
$30
$35 total
includes taxes & fees
Jan 5 - Jan 6, 2026
7.6 out of 10, Good, (458)
7.6/10
Good
(458)
The price is $32
$32
$38 total
includes taxes & fees
Jan 27 - Jan 28, 2026
7.4 out of 10, Good, (327)
7.4/10
Good
(327)
8.0 out of 10, Very Good, (391)
8.0/10
Very Good
(391)
The price is $39
$39
$50 total
includes taxes & fees
Jan 12 - Jan 13, 2026
7.8 out of 10, Good, (233)
7.8/10
Good
(233)
The price is $40
$40
$50 total
includes taxes & fees
Jan 12 - Jan 13, 2026
8.2 out of 10, Very Good, (478)
8.2/10
Very Good
(478)
8.6 out of 10, Excellent, (945)
8.6/10
Excellent
(945)
8.6 out of 10, Excellent, (1037)
8.6/10
Excellent
(1037)
The price is $50
$50
$60 total
includes taxes & fees
Jan 4 - Jan 5, 2026
8.2 out of 10, Very Good, (657)
8.2/10
Very Good
(657)
The price is $43
$43
$52 total
includes taxes & fees
Dec 30 - Dec 31
8.2 out of 10, Very Good, (439)
8.2/10
Very Good
(439)
8.8 out of 10, Excellent, (740)
8.8/10
Excellent
(740)
The price is $44
$44
$53 total
includes taxes & fees
Dec 30 - Dec 31
8.4 out of 10, Very Good, (95)
8.4/10
Very Good
(95)
The price is $44
$44
$53 total
includes taxes & fees
Dec 30 - Dec 31
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Santa Cruz
Apart hotel
Apartment
Pet friendly
Family friendly
Check out reviews of Santa Cruz hotels guests love
Exe Alameda Reforma
10/10 Excellent
"Clean room friendly staff but breakfast was not included 😕 "
InterContinental Presidente Mexico City by IHG
10/10 Excellent
"Excellent location and restaurants"
Casa Olea
10/10 Excellent
"El lugar es muy limpio y amplio"
ULIV Parque Lincoln
10/10 Excellent
"Todos fueron muy amables. El check in súper fácil. El servicio de masajes que ofrecen fue muy bueno!! La ubicación excelente!"
UTOPIC Polanco by ULIV
10/10 Excellent
"Great location. Accommodating and helpful staff. Would come again!"
Hyatt Regency Mexico City
10/10 Excellent
"Great stay"
Holiday Inn Express Mexico Basilica by IHG
10/10 Excellent
"Great stay "
UTOPIC Campos Elíseos by ULIV
10/10 Excellent
"Our room was beautiful and we had a very nice stay. I would recommend this wonderful boutique hotel located conveniently in the Polanco. "
Collection O Hotel Lavanda Anzures
10/10 Excellent
"Buen servicio y atención "
Frequently asked questions
What accommodations do travelers like in Santa Cruz?
La Morada Tepotzotlan Boutique & Spa is an accommodation that is popular with guests.
Can I book refundable hotels in Santa Cruz?
If you want the flexibility to change your travel plans to Santa Cruz, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Santa Cruz be like during my vacation?
April and May are typically the warmest months in Santa Cruz when the average temp is 64°F. January and December are the coldest months when the average temperature is 57°F. August and July are the months with the most rain.
Why should I book my Santa Cruz accommodation with Hotels.com?
There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.