Hotels in Santa Cruz

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Next weekend
Nov 6 - Nov 8
In two weeks
Nov 13 - Nov 15

Where to stay in Santa Cruz?

A bedroom with two beds, a wardrobe, and a door.

1. Hotel Pedregal

Hotel Pedregal
2.0 star property
Colinas del Yaqui
8.2 out of 10, Very good, (64 reviews)
Sophisticated hotel in Nogales, just 5 minutes from the US Consulate. Explore nearby Nogales Mall and Galería Plaza Norte. Enjoy free WiFi throughout your stay, plus convenient amenities like a conference center and daily housekeeping.
The price is $77
$91 total
includes taxes & fees
Nov 2 - Nov 3
Hotel Pedregal
A modern lobby with a reception desk, seating area, and large windows offering a view of the outside.

2. City Express by Marriott Nogales

City Express by Marriott Nogales
3.0 star property
Nueva Nogales
8.8 out of 10, Excellent, (1,003 reviews)
Wake up to a complimentary buffet breakfast at this convenient Nogales hotel. Work out in the fitness center after exploring nearby Nogales Mall and Galería Plaza Norte. Enjoy practical perks including free WiFi and parking with service from the highly-rated staff.
The price is $77
$85 total
includes taxes & fees
Nov 26 - Nov 27
City Express by Marriott Nogales
A pathway flanked by neatly trimmed hedges and palm trees, leading to a building with a modern design and a red and blue sign.

3. Fiesta Inn Nogales

Fiesta Inn Nogales
3.5 star property
Nueva Nogales
8.2 out of 10, Very good, (1,003 reviews)
Experience refreshing swims in the outdoor pool of this convenient Nogales hotel. Enjoy meals at Cafe La Fiesta, workout in the 24-hour fitness center, or unwind at the bar. Located near Nogales Mall and Galería Plaza Norte with free WiFi and parking.
The price is $90
$107 total
includes taxes & fees
Nov 4 - Nov 5
Fiesta Inn Nogales
A restaurant interior with booths, tables, and chairs.

4. Motel San Luis de Nogales

Motel San Luis de Nogales
3.0 star property
Centro
9.4 out of 10, Exceptional, (3 reviews)
The price is $55
$66 total
includes taxes & fees
Nov 2 - Nov 3
Motel San Luis de Nogales
A modern hotel lobby with a reception desk, seating area, and large windows offering a city view.

5. Fairfield Inn & Suites by Marriott Nogales

Fairfield Inn & Suites by Marriott Nogales
3.5 star property
Nogales
8.4 out of 10, Very good, (1,000 reviews)
A well-appointed Nogales hotel offering complimentary perks including daily buffet breakfast, Wi-Fi, and self parking. Visit the on-site fitness center for a workout, and explore nearby attractions like Nogales Mall and Galería Plaza Norte.
The price is $119
$132 total
includes taxes & fees
Nov 20 - Nov 21
Fairfield Inn & Suites by Marriott Nogales
A reception area with a counter, pendant lights, a plant, and a glass wall.

6. City Express by Marriott Cananea

City Express by Marriott Cananea
3.0 star property
Cananea
9.2 out of 10, Wonderful, (411 reviews)
Wake up to complimentary continental breakfast at this contemporary Cananea hotel. Enjoy free WiFi and parking while staying near popular spots like Alboa Lounge and Cinemex. The on-site fitness center keeps your workout routine on track during business trips.
The price is $74
$83 total
includes taxes & fees
Nov 8 - Nov 9
City Express by Marriott Cananea
A cozy living room with a sofa, ottoman, and round coffee table, surrounded by potted plants and a mounted deer head.

7. Hotel Fray Marcos

Hotel Fray Marcos
3.5 star property
Centro
7.8 out of 10, Good, (486 reviews)
Comfort awaits at this Nogales hotel with international cuisine at Fray Mar restaurant and a welcoming bar. The helpful staff provides exceptional service, while free WiFi and valet parking enhance your stay near Pimeria Alta Museum.
The price is $83
$92 total
includes taxes & fees
Nov 2 - Nov 3
Hotel Fray Marcos
A multi-story building with balconies, a brick column, and a table with chairs.

8. Hotel Marques De Cima

Hotel Marques De Cima
2.5 star property
Nogales
8.6 out of 10, Excellent, (925 reviews)
This business-friendly hotel offers free WiFi and parking just minutes from Nogales Mall and Galería Plaza Norte. Enjoy attentive 24-hour service from the highly praised staff during your visit to Nogales.
The price is $96
$106 total
includes taxes & fees
Nov 2 - Nov 3
Hotel Marques De Cima
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Check out reviews of Santa Cruz hotels guests love

Fairfield Inn & Suites by Marriott Nogales

Fairfield Inn & Suites by Marriott Nogales

10/10 Excellent
"The floors need to be updated other than that, everything as well."
Manny 1-night trip
Posted 7 days ago
Fairfield Inn & Suites by Marriott Nogales

Frequently asked questions

Can I book a refundable hotel in Santa Cruz?
If you need the flexibility to change your travel plans to Santa Cruz, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Santa Cruz be like during my trip?
June and July are typically the warmest months in Santa Cruz when the average temp is 78°F. January and December are the coldest months when the average temperature is 51°F. July and August are the months with the most rain.
Why should I book my Santa Cruz accommodation with Hotels.com?
There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.