Hotels in La Crosse

October 2026
November 2026

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Check prices for these dates

This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Where to stay in La Crosse?

1. La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville
Gainesville
$92
$103 total
includes taxes & fees
Oct 3 - Oct 4
La Quinta by Wyndham Gainesville

2. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Alachua
$104
$117 total
includes taxes & fees
Oct 5 - Oct 6
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3. Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
Alachua
$106
$119 total
includes taxes & fees
Oct 11 - Oct 12
Hampton Inn & Suites Alachua I-75

4. Best Western Gateway Grand

Best Western Gateway Grand
Gainesville
$85
$95 total
includes taxes & fees
Oct 6 - Oct 7
Best Western Gateway Grand

5. Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
Gainesville
$105
$118 total
includes taxes & fees
Oct 4 - Oct 5
Drury Inn & Suites Gainesville

6. Quality Inn Alachua - Gainesville Area

Quality Inn Alachua - Gainesville Area
Alachua
$76
$85 total
includes taxes & fees
Oct 20 - Oct 21
Quality Inn Alachua - Gainesville Area

7. Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown
Downtown Gainesville
$98
$110 total
includes taxes & fees
Oct 6 - Oct 7
Hyatt Place Gainesville Downtown

8. Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands
Gainesville
$76
$91 total
includes taxes & fees
Oct 20 - Oct 21
Sleep Inn & Suites University/Shands

9. Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
Gainesville
$88
$99 total
includes taxes & fees
Oct 6 - Oct 7
Country Inn & Suites by Radisson, Gainesville, FL

10. Hotel Indigo Gainesville-Celebration Pointe by IHG

Hotel Indigo Gainesville-Celebration Pointe by IHG
Gainesville
$106
$120 total
includes taxes & fees
Oct 11 - Oct 12
Hotel Indigo Gainesville-Celebration Pointe by IHG

11. Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
Gainesville
$84
$97 total
includes taxes & fees
Oct 20 - Oct 21
Comfort Suites Gainesville near University

12. Holiday Inn Express & Suites Gainesville I-75 by IHG

Holiday Inn Express & Suites Gainesville I-75 by IHG
Gainesville
$114
$128 total
includes taxes & fees
Oct 28 - Oct 29
Holiday Inn Express & Suites Gainesville I-75 by IHG

13. Hampton Inn & Suites Gainesville Downtown University

Hampton Inn & Suites Gainesville Downtown University
Downtown Gainesville
$93
$105 total
includes taxes & fees
Oct 11 - Oct 12
Hampton Inn & Suites Gainesville Downtown University

14. BlueGem Motel

BlueGem Motel
High Springs
$93
$105 total
includes taxes & fees
Oct 5 - Oct 6
BlueGem Motel

15. Hilton Garden Inn Gainesville

Hilton Garden Inn Gainesville
Gainesville
$98
$110 total
includes taxes & fees
Oct 4 - Oct 5
Hilton Garden Inn Gainesville

16. TownePlace Suites by Marriott Gainesville Northwest

TownePlace Suites by Marriott Gainesville Northwest
Gainesville
$114
$128 total
includes taxes & fees
Oct 1 - Oct 2
TownePlace Suites by Marriott Gainesville Northwest

17. SpringHill Suites by Marriott Gainesville

SpringHill Suites by Marriott Gainesville
Gainesville
$85
$96 total
includes taxes & fees
Oct 4 - Oct 5
SpringHill Suites by Marriott Gainesville

18. Depot Village

Depot Village
Gainesville
$67
$143 total
includes taxes & fees
Oct 4 - Oct 5
Depot Village

19. Sweetwater Branch Inn

Sweetwater Branch Inn
Gainesville
$118
$132 total
includes taxes & fees
Oct 6 - Oct 7
Sweetwater Branch Inn

20. Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville
Gainesville
$106
$119 total
includes taxes & fees
Oct 6 - Oct 7
Hilton University of Florida Conference Center Gainesville
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Go beyond your typical stay in La Crosse

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Pet friendly
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Hot tub
Hot tub
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Family friendly
Family friendly
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Apart­ment
Apart­ment
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Cabin
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Cottage
Cottage

Check out reviews of La Crosse hotels guests love

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Alachua

10/10 Exceptional

United States
Enid
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
Alachua

10/10 Exceptional

United States
Jose
Hampton Inn & Suites Alachua I-75

La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville
Gainesville

10/10 Exceptional

United States
Alan
La Quinta by Wyndham Gainesville

Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
Gainesville

10/10 Exceptional

United States
Jennifer
Drury Inn & Suites Gainesville

Fairfield Inn & Suites by Marriott Gainesville I-75

Fairfield Inn & Suites by Marriott Gainesville I-75
Gainesville

10/10 Exceptional

United States
Marita
Fairfield Inn & Suites by Marriott Gainesville I-75

Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown
Downtown Gainesville

10/10 Exceptional

United States
Brandon
Hyatt Place Gainesville Downtown

Best Western Gateway Grand

Best Western Gateway Grand
Gainesville

10/10 Exceptional

United States
jennifer Louise
Best Western Gateway Grand

Hotel Eleo at the University of Florida

Hotel Eleo at the University of Florida
Gainesville

10/10 Exceptional

United States
SO RAH
Hotel Eleo at the University of Florida

Sweetwater Branch Inn

Sweetwater Branch Inn
Gainesville

10/10 Exceptional

United States
Carol
Sweetwater Branch Inn

Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
Gainesville

10/10 Exceptional

United States
Georgette
Country Inn & Suites by Radisson, Gainesville, FL

Hotel Indigo Gainesville-Celebration Pointe by IHG

Hotel Indigo Gainesville-Celebration Pointe by IHG
Gainesville

10/10 Exceptional

United States
Katrina
Hotel Indigo Gainesville-Celebration Pointe by IHG

Home2 Suites by Hilton Gainesville Medical Center

Home2 Suites by Hilton Gainesville Medical Center
Gainesville

10/10 Exceptional

United States
hgamm
Home2 Suites by Hilton Gainesville Medical Center

TownePlace Suites by Marriott Gainesville Northwest

TownePlace Suites by Marriott Gainesville Northwest
Gainesville

10/10 Exceptional

United States
Lyla
TownePlace Suites by Marriott Gainesville Northwest

Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands
Gainesville

10/10 Exceptional

United States
Lisa
Sleep Inn & Suites University/Shands

Aloft by Marriott Gainesville University Area

Aloft by Marriott Gainesville University Area
Gainesville

10/10 Exceptional

United States
Luis
Aloft by Marriott Gainesville University Area

Frequently Asked Questions

What hotels do travelers recommend in La Crosse?

Can I book a refundable accommodation in La Crosse?

If you need the flexibility to change your travel plans to La Crosse, most accommodations offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in La Crosse be like during my vacation?

The warmest months in La Crosse are usually July and August with an average temp of 80°F. January and February are the chilliest months when the average temp is 59°F. The rainiest months are August and June.

Why should I book my La Crosse hotel through Hotels.com?

There are plenty of reasons to book your La Crosse travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.