Hotels in Mayo
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Holiday Inn Express Gaffney by IHG
Holiday Inn Express Gaffney by IHG
2.5 star property
Gaffney
8.8 out of 10, Excellent, (427)
8.8/10
Excellent
(427)
The price is $83
$83
$90 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Tru by Hilton Spartanburg
Tru by Hilton Spartanburg
2.5 star property
Spartanburg
9.2 out of 10, Wonderful, (832)
9.2/10
Wonderful
(832)
The price is $110
$110
$122 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Comfort Suites At WestGate Mall
Comfort Suites At WestGate Mall
2.5 star property
Spartanburg
8.2 out of 10, Very Good, (1000)
8.2/10
Very Good
(1000)
The price is $94
$94
$104 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Best Western Plus Spartanburg
Best Western Plus Spartanburg
2.5 star property
Spartanburg
8.4 out of 10, Very Good, (1004)
8.4/10
Very Good
(1004)
The price is $87
$87
$99 total
includes taxes & fees
Jan 4 - Jan 5, 2026
AC Hotel by Marriott Spartanburg
AC Hotel by Marriott Spartanburg
3.5 star property
Spartanburg
9.2 out of 10, Wonderful, (587)
9.2/10
Wonderful
(587)
The price is $135
$135
$150 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Hilton Garden Inn Spartanburg
Hilton Garden Inn Spartanburg
3.0 star property
Spartanburg
9.4 out of 10, Exceptional, (493)
9.4/10
Exceptional
(493)
The price is $118
$118
$131 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Spartanburg Marriott
Spartanburg Marriott
3.5 star property
Spartanburg
8.6 out of 10, Excellent, (1001)
8.6/10
Excellent
(1001)
The price is $144
$144
$160 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hampton Inn Spartanburg-North I-85
Hampton Inn Spartanburg-North I-85
2.5 star property
Spartanburg
8.8 out of 10, Excellent, (1000)
8.8/10
Excellent
(1000)
The price is $78
$78
$86 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Best Western Spartanburg Northwest
Best Western Spartanburg Northwest
3.0 star property
Spartanburg
8.2 out of 10, Very Good, (824)
8.2/10
Very Good
(824)
The price is $92
$92
$102 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Residence Inn by Marriott Spartanburg Westgate
Residence Inn by Marriott Spartanburg Westgate
3.0 star property
Spartanburg
9.4 out of 10, Exceptional, (214)
9.4/10
Exceptional
(214)
The price is $139
$139
$154 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
2.5 star property
Spartanburg
8.6 out of 10, Excellent, (866)
8.6/10
Excellent
(866)
The price is $101
$101
$112 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Four Points by Sheraton Spartanburg
Four Points by Sheraton Spartanburg
3.0 star property
Spartanburg
9.4 out of 10, Exceptional, (439)
9.4/10
Exceptional
(439)
The price is $119
$119
$132 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Quality Inn Forest City
Quality Inn Forest City
2.5 star property
Forest City
7.6 out of 10, Good, (298)
7.6/10
Good
(298)
The price is $62
$62
$70 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Holiday Inn Spartanburg Northwest by IHG
Holiday Inn Spartanburg Northwest by IHG
2.5 star property
Spartanburg
7.6 out of 10, Good, (832)
7.6/10
Good
(832)
The price is $85
$85
$94 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Baymont by Wyndham Forest City
Baymont by Wyndham Forest City
2.5 star property
Forest City
7.4 out of 10, Good, (706)
7.4/10
Good
(706)
The price is $60
$60
$68 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Home2 Suites by Hilton Duncan
Home2 Suites by Hilton Duncan
3.0 star property
Duncan
9.4 out of 10, Exceptional, (283)
9.4/10
Exceptional
(283)
The price is $112
$112
$124 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Comfort Inn & Suites Spartanburg North
Comfort Inn & Suites Spartanburg North
2.5 star property
Spartanburg
7.8 out of 10, Good, (972)
7.8/10
Good
(972)
The price is $86
$86
$96 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hampton Inn Gaffney
Hampton Inn Gaffney
2.5 star property
Gaffney
8.8 out of 10, Excellent, (673)
8.8/10
Excellent
(673)
The price is $98
$98
$106 total
includes taxes & fees
Jan 18 - Jan 19, 2026
University Inn
University Inn
2.5 star property
Shelby
8.6 out of 10, Excellent, (450)
8.6/10
Excellent
(450)
The price is $95
$95
$107 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hampton Inn & Suites Forest City
Hampton Inn & Suites Forest City
2.5 star property
Forest City
9.4 out of 10, Exceptional, (419)
9.4/10
Exceptional
(419)
The price is $130
$130
$147 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Mayo
Pet friendly
Family friendly
Check out reviews of Mayo hotels guests love
Four Points by Sheraton Spartanburg
10/10 Excellent
"Very nice hotel"
Tru by Hilton Spartanburg
10/10 Excellent
"It was good but simple! Might could add some type of potatoes to the menu "
ECHO Suites Extended Stay by Wyndham Spartanburg
10/10 Excellent
"Very clean rooms, bedding was comfortable and pet friendly was a plus and needed. "
Comfort Inn & Suites Spartanburg North
10/10 Excellent
"Great location and nice place to stay especially for the price, very reasonable!"
Holiday Inn Express Gaffney by IHG
10/10 Excellent
"X"
Hampton Inn Spartanburg-North I-85
10/10 Excellent
"The staff was courteous in the room was spotless!"
Sleep Inn Spartanburg Southwest
10/10 Excellent
"Beautiful, cheap, clean, incredibly nice…"
Extended Stay America Premier Suites - Greenville - Spartanburg - I-85
10/10 Excellent
"excellent service"
AC Hotel by Marriott Spartanburg
10/10 Excellent
"The gentleman at the front desk when I checked in made me feel very comfortable. He was so chill.
It was a great stay"
Frequently asked questions
What accommodations do travelers recommend in Mayo?
Can I book a refundable hotel in Mayo?
If you're looking for the flexibility to change your plans to Mayo, most hotels provide refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Mayo be like during my visit?
July and August are typically the warmest months in Mayo when the average temp is 77°F. January and February are the coldest months when the average temperature is 46 °F. December and April are the months with the most rain.
Why should I book my Mayo accommodation with Hotels.com?
There are lots of reasons to book your Mayo trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.