A covered bridge with a sign reading "GUTLER-DONAHUE BRIDGE Built 1870" in a forested area.

Hotels in Saint Charles

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A spacious lobby with high ceilings, large windows, and a chandelier.

A grand lobby with a piano, a chandelier, and a seating area.

A double door entrance to a hotel with a sign above reading "PROUDFOOT & BIRD".

A spacious lobby with a central round table, green seating, and large arched windows.

1. Hotel Fort Des Moines, Curio Collection by Hilton

Downtown Des Moines

$144

$161 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with a large bed, a nightstand, a wall-mounted TV, and a window with curtains.

A gym with treadmills, elliptical machines, and a water dispenser.

An indoor swimming pool with clear windows, white chairs, and a blue and white color scheme.

A Days Inn & Suites sign, a parking lot, and a building with multiple floors and windows.

2. Days Inn & Suites by Wyndham Des Moines Airport

Greater South Side

$65

$73 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel room with a large bed, a built-in desk, a vanity with a bathtub, and a large window with curtains.

A hallway with vending machines and a clean, tiled floor.

A multi-story hotel with a modern design, featuring a stone facade and multiple windows.

A restaurant with multiple tables and chairs, a kitchen area, and a stone accent wall.

3. Sonesta Essential Des Moines

Lovington

$68

$79 total

includes taxes & fees

Oct 8 - Oct 9

An indoor pool with slides and a ship-themed play area.

A spacious restaurant with wooden tables and chairs, a stone wall, and a large window overlooking the dining area.

A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.

A bar area with a central counter, multiple bar stools, and a decorative figure on top.

4. Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Urbandale

$71

$80 total

includes taxes & fees

Oct 18 - Oct 19

A spacious, modern interior with a long wooden table and bar stools, a seating area with sofas, and a kitchen area with a countertop and shelving.

A hotel room with two beds, a desk, a chair, and a large window.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables.

5. La Quinta Inn & Suites by Wyndham Johnston

Johnston

A building with a sign reading "WILDWOOD LODGE."

A cozy living room with a stone fireplace, a sofa, and a coffee table.

A spacious lobby with a reception desk, seating area, and a view of the outdoors.

An indoor swimming pool with a stone-tiled floor, red-framed windows, and a sign reading "LAKE WILDWOOD".

6. Wildwood Lodge

Clive

$104

$116 total

includes taxes & fees

Oct 11 - Oct 12

An indoor swimming pool with a 30 ft depth sign, a reception area, and a 'No Lifeguard' warning sign.

A hotel room with two beds, a desk, a television, and a dresser.

A lobby with striped orange chairs, a green ottoman, and a fireplace.

A lobby with a checkered armchair, a yellow sofa, a glass-top coffee table, and a cabinet with glass doors.

7. Drury Inn & Suites West Des Moines

West Des Moines

$100

$112 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor dining area with a table set for two, featuring a cocktail and candles.

A multi-level hotel atrium with balconies, indoor plants, and artwork on the walls.

A multi-level hotel lobby with a central pool, dining area, and a bar.

A row of tables with metallic pitchers and crystal glassware, set against a purple-lit background.

8. Embassy Suites Hotel Des Moines Downtown

Downtown Des Moines

$130

$146 total

includes taxes & fees

Oct 11 - Oct 12

An outdoor seating area with yellow chairs and a colorful sofa, a fire pit, and a wooden ceiling with hanging lights.

A hotel room with a bed, a sofa, a desk, and a television.

A modern lounge area with a sofa, ottomans, and tables, featuring a mix of red and yellow chairs.

A modern restaurant with a long wooden table and chairs, a counter with a beverage dispenser, and shelves with bowls and glasses.

9. Home2 Suites by Hilton Des Moines at Drake University

Drake

$105

$117 total

includes taxes & fees

Nov 2 - Nov 3

A luxurious living room with a stone fireplace, a large mirror, and two blue armchairs.

A hotel facade with a brick exterior, large windows, and a prominent entrance sign.

A spacious hotel lobby with high ceilings, ornate chandeliers, and a bar area.

10. Des Lux Hotel

Downtown Des Moines

$169

$189 total

includes taxes & fees

Oct 4 - Oct 5

An indoor swimming pool with tiled flooring, a wooden ceiling, and a seating area with chairs and umbrellas.

A multi-story brick building with a covered entrance, flagpoles, and a landscaped area with trees.

A spacious living area with a staircase, a fireplace, a wooden desk, and a dining area.

A reception area with a wooden counter, overhead pendant lights, framed pictures on the wall, and a refrigerator stocked with beverages.

11. Country Inn & Suites by Radisson, Des Moines West, IA

Clive

$81

$91 total

includes taxes & fees

Nov 1 - Nov 2

An indoor swimming pool with a waterfall feature, surrounded by Adirondack chairs and a wooden deck.

A hotel room with a large bed, a fireplace, a TV, and a jacuzzi.

A wooden interior with a reception desk, a mounted moose head, and a staircase.

A building with a sign reading "The Cottages" and a covered outdoor seating area.

12. Stoney Creek Hotel Des Moines - Johnston

Johnston

$109

$122 total

includes taxes & fees

Oct 4 - Oct 5

A spacious lobby with a high ceiling, a central seating area with a blue sofa and chairs, a dining area, and a staircase leading to an upper level.

A hotel dining area with multiple tables and chairs, a kitchen area with a microwave and refrigerator, and a colorful carpet.

A multi-story hotel with a prominent entrance, a large glass facade, and a parking lot.

A spacious lobby with a curved blue sofa, a round coffee table, and a seating area with chairs. There is a staircase with a railing leading to an upper level.

13. Fairfield Inn and Suites by Marriott Des Moines West

West Des Moines

$97

$108 total

includes taxes & fees

Oct 18 - Oct 19

A spacious indoor area with multiple levels, featuring a central open space with tables and chairs, surrounded by balconies and a large, colorful ceiling structure.

A gym with treadmills, elliptical machines, and free weights.

A modern hotel entrance with a glass facade, outdoor seating, and a staircase leading to the entrance.

A spacious lobby with large windows, a potted plant, and a seating area.

14. Holiday Inn Des Moines-Airport/Conf Center by IHG

Greater South Side

$114

$128 total

includes taxes & fees

Oct 26 - Oct 27

A living room with a sofa, a patterned armchair, a coffee table, and a dining area with chairs and a table.

An indoor swimming pool with blue lounge chairs, a red brick border, and a ceiling with recessed lighting.

A breakfast area with a chalkboard sign, coffee machines, and a fruit bowl.

An outdoor patio area with picnic tables and benches, large windows, and a building with a brick facade in the background.

15. AmericInn by Wyndham Johnston Des Moines

Johnston

$60

$67 total

includes taxes & fees

Oct 8 - Oct 9

An outdoor dining area with tables and chairs, a large umbrella, and a TV screen.

A modern restaurant with a large, abstract wall art piece, multiple seating areas, and a staircase leading to an upper level.

A modern hotel with a prominent 'Hilton' sign, large windows, and a covered outdoor area with seating.

A modern hotel room with a large city view, a sofa, a dining area, and a small table with a decorative item.

16. Hilton Des Moines Downtown

Downtown Des Moines

$136

$157 total

includes taxes & fees

Oct 11 - Oct 12

An outdoor patio with modern seating and a built-in fireplace.

A modern restaurant with a long counter, multiple seating areas, and a kitchen visible in the background.

An indoor swimming pool with clear glass walls, a lifeguard chair, and a pool ladder.

A La Quinta hotel entrance with a modern design, numbered 1390, and a landscaped entrance area.

17. La Quinta Inn & Suites by Wyndham Des Moines West Clive

Clive

$78

$88 total

includes taxes & fees

Nov 1 - Nov 2

A bar area with multiple screens displaying sports and news, a cash register, and bar stools.

A lobby with a stone wall, a fireplace, a TV, red sofas, and two lamps.

A white pergola with a view of a lake and trees.

A hotel with a pool area, outdoor seating, and a building with multiple floors and windows.

18. Lakeside Hotel Casino, a Travelodge by Wyndham

Osceola

$72

$95 total

includes taxes & fees

Oct 4 - Oct 5

A sunroom with a glass ceiling, wicker furniture, and potted plants.

A hotel room with a bed, a blue armchair, a desk, and a nightstand.

An indoor swimming pool with clear glass walls, white lounge chairs, and a tiled floor.

A spacious lobby with a high ceiling, a seating area with sofas and ottomans, a reception desk, and a staircase to an upper level.

19. Baymont by Wyndham Des Moines Airport

Southwestern Hills

$83

$93 total

includes taxes & fees

Oct 25 - Oct 26

A spacious hotel lobby with a blue sofa, a grey armchair, and a flat-screen TV mounted on a textured wall.

A hotel reception area with a coffee station featuring multiple coffee machines, a beverage dispenser, and a buffet setup with bowls and napkins.

A hotel lobby with a blue sofa, a beige armchair, a flat-screen TV mounted on a textured wall, a fireplace, and a dining area in the background.

A Comfort Inn hotel with a modern facade, multiple floors, and a parking lot with cars.

20. Comfort Inn & Suites Event Center

Downtown Des Moines

$93

$104 total

includes taxes & fees

Oct 25 - Oct 26

View all properties

Go beyond your typical stay in Saint Charles

Top landmarks in Saint Charles

Imes Bridge

7.8/10 (17 reviews)

If you're planning a bit of sightseeing during your trip, head to Imes Bridge— just one of the landmarks located 0.5 mi (0.9 km) from central Saint Charles.

See properties

Learn more about Saint Charles

The region around Saint Charles is home to attractions such as Imes Bridge and John Wayne Birthplace Museum.

See all hotels in Saint Charles

Check out reviews of Saint Charles hotels guests love

A hotel entrance with a stone facade, a sign above the entrance, and a covered walkway.

A hotel room with a large bed, a desk with a chair, a lamp, and a window with curtains.

A buffet setup with a bowl of oranges and a container of fruit.

A hotel lobby with a reception desk, a brown sofa, a small armchair, a coffee table, and a fireplace.

Cobblestone Inn & Suites - Winterset, IA

Winterset

10/10 Exceptional

Anonymous traveler

A covered outdoor area with a wooden ceiling and brick pillars, overlooking a parking lot with cars and a distant landscape.

A bathroom with a toilet, a shower with a curtain, and a towel rack with towels.

A hotel room with two beds, a desk with a computer, a TV, and a window with curtains.

Covered Bridge Inn

Winterset

10/10 Exceptional

We didn't arrive till nearly 1am but they came right up to the desk when we rang the bell. Very friendly. The room was clean and larger than many Hamptons I've been in. The beds were comfortable, there was a coffee pot, shampoo and blow dryer, desk, side chair, and even a free breakfast which I don't always expect to see in a Super 8. It just felt very comfortable. We were there to go to the State Fair and the drive from Winterset to Des Moines was through pretty countryside.

An outdoor patio with brick walls, ceiling fans, string lights, and outdoor seating.

A hotel entrance with a sign reading "hotel pommier."

A modern kitchen with grey cabinets, a granite countertop, and various appliances including a microwave, oven, and toaster.

A modern hotel lobby with a seating area, a reception desk, and a visible exit sign.

Hotel Pommier Indianola

Indianola

10/10 Exceptional

Anonymous traveler

Baymont by Wyndham Des Moines Airport

Southwestern Hills

10/10 Exceptional

Andrew

A reception desk with a wooden backdrop, a framed map, and a 'home' sign.

A row of single-story buildings with green roofs and white trim, each with a porch and potted plants.

A hotel room with a bed, a desk with a computer, a ceiling fan, and two wall-mounted lights.

A bathroom with a sink, mirror, and toilet. There is a microwave on the left and a towel rack above the sink.

Evergreen Inn

Osceola

10/10 Exceptional

Sharon

An outdoor patio with a fire pit, wooden pergola, and seating area.

A hotel with a covered entrance, multiple floors, and a sign reading 'COUNTRY INN & SUITES BY PADIBOSON.'

A modern living room with a fireplace, two sofas, a coffee table, and a bookshelf.

A hotel room with two beds, a desk with a chair, a television, and a large window with curtains.

Country Inn & Suites by Radisson, Indianola, IA

Indianola

10/10 Exceptional

Shane

Drury Inn & Suites West Des Moines

West Des Moines

10/10 Exceptional

Judith

Lakeside Hotel Casino, a Travelodge by Wyndham

Osceola

10/10 Exceptional

Jean

A hotel lobby with a reception desk, seating area, and a wall with a floral mural.

A hotel room with a large bed, two bedside tables with lamps, a chair, a desk, and a large window with curtains.

A spacious lobby with multiple seating areas, including sofas and tables, and a visible kitchen area in the background.

A building entrance with a stone facade, large glass doors, and potted plants.

Sleep Inn & Suites West Des Moines near Jordan Creek

West Des Moines

10/10 Exceptional

James

A Holiday Inn Express & Suites building with a modern design, featuring a stone facade and a covered entrance.

A swimming pool with clear blue water, surrounded by lounge chairs and a wooden cabinet.

A modern breakfast area with a self-serve station, a large apple-shaped sign, and a kitchen display.

A lobby with a brown sofa, grey armchairs, a small round table, and a vending machine.

Holiday Inn Express & Suites West Des Moines - Jordan Creek by IHG

West Des Moines

10/10 Exceptional

Julie

An indoor swimming pool with tiled floors, clear water, and a blue chair by the pool.

A reception area with a granite counter, a 'Quality' sign, a phone, and a door.

A hotel room with two beds, a desk, and a chair.

A vending machine with a Coca-Cola Ice Cold section and a beverage dispenser.

Quality Inn Indianola

Indianola

10/10 Exceptional

Barb

A modern lobby with a sofa, chairs, a lamp, and a wall with a floral pattern.

A hotel room with a bed, a desk, a chair, and a nightstand with lamps.

A reception desk with a 'Welcome' mat, a sign for 'Sleep Inn & Suites', and a door to the right.

A modern restaurant with a variety of seating options including tables, chairs, and sofas.

Sleep Inn Waukee-West Des Moines

Waukee

10/10 Exceptional

Janet

A corner room with two blue chairs, a small table, and a window with curtains.

A hotel room with two beds, a television, and a small table.

A bathroom with a bathtub, toilet, and sink.

A reception area with a wooden desk, a statue, a potted plant, and a wall clock.

Blue Haven Motel

Osceola

10/10 Exceptional

Jodi

A modern hotel lobby with a round coffee table, sofas, and a TV mounted on the wall.

An indoor swimming pool with clear water, surrounded by lounge chairs and a tiled floor.

A hotel with a stone facade, a covered entrance, and an American flag.

A buffet setup with various food items, including fruits and cereals, and a soup station.

Homewood Suites by Hilton Des Moines Airport

Des Moines

10/10 Exceptional

Theodore

Wildwood Lodge

Clive

10/10 Exceptional

Tim

Days Inn & Suites by Wyndham Des Moines Airport

Greater South Side

10/10 Exceptional

Benjamin

Frequently Asked Questions

Can I book a refundable hotel in Saint Charles?

If you're looking for the flexibility to change your plans to Saint Charles, most hotels provide refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Saint Charles be like during my trip?

The warmest months in Saint Charles are usually July and August with an average temp of 72°F. January and February are the chilliest months when the average temp is 29°F. The rainiest months are May and June.

Why should I book my Saint Charles hotel through Hotels.com?

There are plenty of reasons to book your Saint Charles travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.