Hotels in Santee

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Check prices for these dates

Tonight
Nov 2 - Nov 3
Tomorrow
Nov 3 - Nov 4
This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

Where to stay in Santee?

A spacious kitchen with a large island, modern pendant lights, and a ceiling fan.

1. Lewis and Clark Resort

Lewis and Clark Resort
2.5 star property
Yankton
8.8 out of 10, Excellent, (355 reviews)
Set along Lewis and Clark Lake, this resort combines outdoor adventure with comfortable accommodations. Access the marina directly, cool off in the seasonal pool, then enjoy a meal at the restaurant. Free WiFi and parking make exploring nearby recreation areas effortless.
The price is $113
$120 total
includes taxes & fees
Nov 3 - Nov 4
Lewis and Clark Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Go beyond your typical stay in Santee

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Pet friendly
Pet friendly
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Pool
Pool

Frequently Asked Questions

Can I book refundable hotels in Santee?

If you want the flexibility to change your plans to Santee, most hotels provide refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Santee be like during my visit?

The warmest months in Santee are usually July and August with an average temp of 72°F. January and February are the chilliest months when the average temp is 26°F. The rainiest months are June and May.

Why should I book my Santee accommodation with Hotels.com?

There are lots of reasons to book your Santee trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.