Top 10 Hotels in Mercer, MO in 2026 (from $65)

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Where to stay in Mercer?

A living room with a stone wall, a fireplace, a flat-screen TV, and two patterned armchairs.

A bar area with a stone wall, a flat-screen TV, and a variety of bottles and glasses.

A hotel room with a bed, a desk, a television, a sofa, and a large window with curtains.

A hotel dining area with multiple tables and chairs, a television mounted on the wall, and a fireplace in the background.

1. Cobblestone Inn & Suites - Lamoni

Lamoni

$140

$157 total

includes taxes & fees

Oct 21 - Oct 22

A hallway with wooden flooring, a Christmas tree, and various furniture including a desk, chairs, and lamps.

A dining area with a large table set for a meal, surrounded by chairs.

A spacious living room with a large red rug, wooden furniture, and a chandelier.

A residential garden with a metal gate, various flowering plants, and a lawn.

2. Inn of the Six-Toed Cat

Allerton

$66

$69 total

includes taxes & fees

Oct 21 - Oct 22

A reception area with a stone counter, a clock, and a desk with a computer.

A modern kitchen with granite countertops, built-in cabinets, a coffee machine, a juice dispenser, and a microwave.

A two-story building with a covered patio area, a brick facade, and a large window.

A hotel room with a bed, bedside lamps, a phone, a window with curtains, and a wall-mounted air conditioner.

3. Travelodge by Wyndham Lamoni

Lamoni

$98

$110 total

includes taxes & fees

Nov 11 - Nov 12

A coffee station with a coffee maker, cups, and a mug. There are baskets with coffee packets and a coffee pot on the counter.

A cozy room with a leather armchair, a small wooden table with a lamp, and a view of the outdoors through a window with red curtains.

A room with wooden walls and ceiling, a large window with a view of a red building, and a ceiling fan.

A covered outdoor patio with a grill, seating, and a view of the surrounding greenery.

4. Little River Inn Motel & Guest House

Leon

$89

$98 total

includes taxes & fees

Oct 21 - Oct 22

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Go beyond your typical stay in Mercer

Check out reviews of Mercer hotels guests love

Cobblestone Inn & Suites - Lamoni

Lamoni

10/10 Exceptional

Anonymous traveler

Inn of the Six-Toed Cat

Allerton

10/10 Exceptional

Dexter

Travelodge by Wyndham Lamoni

Lamoni

10/10 Exceptional

John

Frequently Asked Questions

What hotels do travelers recommend in Mercer?

Guests like The Lodge in Powersville w/ Game Room & Fire Pit and Rustic Powersville Cabin: Secluded Countryside!.

Can I book a refundable accommodation in Mercer?

If you're looking for the flexibility to change your travel plans to Mercer, most hotels offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Mercer be like during my visit?

July and August are typically the warmest months in Mercer when the average temp is 72°F. January and February are the coldest months when the average temperature is 30°F. May and June are the months with the most rain.

Why should I book my Mercer hotel through Hotels.com?

There are lots of reasons to book your Mercer trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.