Hotels in Byron

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America's Stay Inn Stewartville
America's Stay Inn Stewartville
2.5 star property
Stewartville
8.0 out of 10, Very Good, (441 reviews)
Wake up to a complimentary continental breakfast at this Stewartville hotel before heading to Mayo Clinic, just a short drive away. Clean rooms provide a comfortable retreat after visits to nearby Maple Valley Golf & Country Club.
The price is $70
$75 total
includes taxes & fees
May 14 - May 15
America's Stay Inn Stewartville
Americas Best Value Inn Zumbrota
Americas Best Value Inn Zumbrota
2.0 star property
Zumbrota
7.2 out of 10, Good, (527 reviews)
This quiet motel offers complimentary continental breakfast, WiFi, and parking near Covered Bridge Park. Outdoor enthusiasts will appreciate the nearby snowmobiling opportunities, while attentive staff ensure a comfortable, tranquil retreat.
The price is $60
$64 total
includes taxes & fees
May 14 - May 15
Americas Best Value Inn Zumbrota
Baymont by Wyndham Kasson Rochester Area
Baymont by Wyndham Kasson Rochester Area
2.5 star property
Kasson
6.6 out of 10, (392 reviews)
Discover peaceful comfort at this family-friendly retreat with an indoor pool for morning swims and a hot tub for evening relaxation. Free breakfast, WiFi, and parking enhance your stay near Zumbro Valley Golf Course and Sunset Trail Park.
The price is $60
$65 total
includes taxes & fees
Jun 1 - Jun 2
Baymont by Wyndham Kasson Rochester Area
Hampton Inn Rochester-South
Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1,000 reviews)
Unwind in this tranquil retreat just 5 minutes from Mayo Clinic. After enjoying the free breakfast, take a refreshing dip in the indoor pool or relax in the hot tub. The helpful staff, free WiFi, and convenient parking enhance your stay near Apache Mall.
The price is $90
$104 total
includes taxes & fees
Jun 5 - Jun 6
Hampton Inn Rochester-South
Comfort Inn & Suites Rochester South Mayo Clinic
Comfort Inn & Suites Rochester South Mayo Clinic
2.0 star property
Rochester
8.8 out of 10, Excellent, (1,006 reviews)
Conveniently located just 0.9 mi from the airport, with a free shuttle service during limited hours. Unwind in the indoor pool and hot tub after exploring nearby Mayo Clinic. Guests love the helpful staff, clean rooms, and free amenities including breakfast, WiFi, and parking.
The price is $66
$76 total
includes taxes & fees
May 31 - Jun 1
Comfort Inn & Suites Rochester South Mayo Clinic
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
2.0 star property
Rochester
8.0 out of 10, Very Good, (1,000 reviews)
Peaceful accommodations just a 10-minute drive from Mayo Clinic with free WiFi, parking, and daily on-the-go breakfast. The fitness center offers workout options while nearby restaurants and attractions provide convenient exploration opportunities.
The price is $70
$80 total
includes taxes & fees
May 17 - May 18
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Birch Hill Suite Rochester – Med City
Birch Hill Suite Rochester – Med City
2.5 star property
Rochester
7.0 out of 10, Good, (37 reviews)
This modern Rochester hotel offers free WiFi and parking, plus a fitness center for health-conscious guests. Located within 10 minutes of Mayo Clinic and Saint Marys Campus, it's also near Marcus Cinema and Olmsted County Fairgrounds.
The price is $64
$74 total
includes taxes & fees
May 14 - May 15
Birch Hill Suite Rochester – Med City
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.4 out of 10, Good, (1,061 reviews)
Situated just a 10-minute drive from Mayo Clinic, this hotel offers a complimentary buffet breakfast each morning. Guests appreciate the spotless rooms, free WiFi, and parking. The fitness center and proximity to local attractions add extra value.
The price is $70
$80 total
includes taxes & fees
May 17 - May 18
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
3.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (704 reviews)
Conveniently located just 5 minutes from Mayo Clinic, this hotel offers free breakfast and area shuttle service. Relax in the indoor pool after a busy day, or maintain your workout at the fitness center. In-room comforts include refrigerators and microwaves.
The price is $103
$118 total
includes taxes & fees
May 22 - May 23
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Quality Inn near Medical Center
Quality Inn near Medical Center
2.5 star property
Rochester
7.8 out of 10, Good, (881 reviews)
Just 10 minutes from Mayo Clinic, this Rochester hotel offers comfort with an indoor pool, fitness center, and complimentary breakfast. Business travelers appreciate the free parking and helpful staff, while nearby attractions provide leisure options.
The price is $63
$72 total
includes taxes & fees
Jun 1 - Jun 2
Quality Inn near Medical Center
Motel 6 Rochester, MN
Motel 6 Rochester, MN
2.0 star property
Rochester
5.8 out of 10, (427 reviews)
This Rochester motel provides free WiFi and parking, plus 24-hour front desk service for late arrivals. Located near Mayo Clinic Hospital and Assisi Heights, it's a practical base for medical appointments or exploring nearby Kutzky Park Tennis Center.
The price is $55
$63 total
includes taxes & fees
May 15 - May 16
Motel 6 Rochester, MN
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.0 out of 10, Very Good, (1,321 reviews)
Steps from Mayo Clinic, this tranquil hotel offers an indoor pool and on-site dining at Crooked Pint Ale House. Rooms include microwaves and refrigerators while the quiet environment ensures restful recovery. Free breakfast and parking add convenience.
The price is $76
$88 total
includes taxes & fees
May 31 - Jun 1
AmericInn by Wyndham Rochester Near Mayo Clinic
Americas Best Value Inn & Suites Spring Valley
Americas Best Value Inn & Suites Spring Valley
2.0 star property
Spring Valley
8.2 out of 10, Very Good, (444 reviews)
Stretch out in Spring Valley at this well-maintained motel offering free continental breakfast, WiFi, and parking. Work out in the fitness center before exploring nearby Masonic Park or Four Daughters Vineyard & Winery. Just 26 minutes from Rochester International Airport.
The price is $81
$89 total
includes taxes & fees
May 24 - May 25
Americas Best Value Inn & Suites Spring Valley
Hampton Inn & Suites Rochester-North
Hampton Inn & Suites Rochester-North
2.5 star property
Rochester
9.2 out of 10, Wonderful, (1,004 reviews)
Just a short drive from Mayo Clinic, this welcoming hotel offers a refreshing indoor pool and soothing hot tub. Guests love the complimentary breakfast, free WiFi, and convenient parking. The helpful staff and 24-hour fitness center ensure a comfortable stay near Northern Hills Golf Course.
The price is $110
$126 total
includes taxes & fees
May 24 - May 25
Hampton Inn & Suites Rochester-North
Comfort Inn & Suites West - Medical Center
Comfort Inn & Suites West - Medical Center
3.0 star property
Rochester
9.0 out of 10, Wonderful, (602 reviews)
Conveniently located just 10 minutes from Mayo Clinic, this Rochester hotel offers comfort with an indoor pool and relaxing hot tub. Free parking and a fitness center enhance your stay while medical facilities remain easily accessible.
The price is $100
$115 total
includes taxes & fees
Jun 7 - Jun 8
Comfort Inn & Suites West - Medical Center
Sleep Inn & Suites West-Near Medical Center
Sleep Inn & Suites West-Near Medical Center
2.5 star property
Rochester
9.0 out of 10, Wonderful, (637 reviews)
Just minutes from world-renowned Mayo Clinic, this hotel offers an indoor pool for year-round relaxation. Guests love the helpful staff and spotless rooms. Enjoy free breakfast, WiFi, parking, and easy access to Badger Ridge Park.
The price is $82
$94 total
includes taxes & fees
Jun 7 - Jun 8
Sleep Inn & Suites West-Near Medical Center
Red Carpet Inn Rochester
Red Carpet Inn Rochester
2.0 star property
Rochester
7.6 out of 10, Good, (539 reviews)
The price is $60
$69 total
includes taxes & fees
May 14 - May 15
Red Carpet Inn Rochester
Spark by Hilton Rochester South
Spark by Hilton Rochester South
3.0 star property
Rochester
9.4 out of 10, Exceptional, (467 reviews)
Within 10 minutes of Mayo Clinic, this welcoming Rochester hotel offers free breakfast, WiFi, and parking. Swim in the indoor pool, stay fit at the on-site gym, and experience friendly service that guests consistently praise.
The price is $77
$89 total
includes taxes & fees
Jun 7 - Jun 8
Spark by Hilton Rochester South
MainStay Suites Rochester South Mayo Clinic
MainStay Suites Rochester South Mayo Clinic
2.5 star property
Rochester
7.0 out of 10, Good, (109 reviews)
This extended-stay hotel offers free WiFi and parking only 10 minutes from Mayo Clinic. Spacious suites provide a home base while you're near major medical facilities, with Marcus Rochester Cinema and Olmsted County Fairgrounds close by.
The price is $59
$68 total
includes taxes & fees
May 19 - May 20
MainStay Suites Rochester South Mayo Clinic
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
Rochester
8.2 out of 10, Very Good, (913 reviews)
Minutes from Mayo Clinic and St. Mary's Campus, this hotel offers free breakfast, parking, and WiFi. Enjoy a swim in the indoor pool, unwind in the hot tub, or grab American cuisine at Wildwood Sports Bar. Nearby restaurants, shops, and attractions await.
The price is $94
$108 total
includes taxes & fees
May 17 - May 18
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

What hotels do travelers recommend in Byron?
Can I book refundable accommodations in Byron?
If you're looking for the flexibility to change your plans to Byron, most properties provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Byron be like during my vacation?
July and August are typically the warmest months in Byron when the average temp is 67°F. January and February are the coldest months when the average temperature is 21°F. June and May are the months with the most rain.
Why should I book my Byron hotel with Hotels.com?
There are lots of reasons to book your Byron trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.