Hotels in Santa Clara

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Riande Aeropuerto Hotel & Casino
Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.4 out of 10, Very Good, (1,856 reviews)
  • cleanliness
    Chic airport sanctuary with lush gardens and a serene poolside oasis to unwind.
The price is $125
$138 total
includes taxes & fees
Mar 15 - Mar 16
Riande Aeropuerto Hotel & Casino
Courtyard by Marriott Panama Metromall
Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
9.0 out of 10, Wonderful, (1,002 reviews)
The price is $118
$130 total
includes taxes & fees
Mar 27 - Mar 28
Courtyard by Marriott Panama Metromall
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (674 reviews)
  • cleanliness
    Luxury Panama City escape with golf course, spa, and poolside relaxation.
The price is $224
$247 total
includes taxes & fees
Apr 1 - Apr 2
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Arcadia Condo Suites
Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (235 reviews)
  • cleanliness
    Located just a short drive from Multiplaza Pacific Mall in Panama City, enjoy apartment living with a rooftop terrace.
The price is $120
$178 total
includes taxes & fees
Mar 14 - Mar 15
Arcadia Condo Suites
The Westin Panama
The Westin Panama
4.0 star property
Costa del Este
9.0 out of 10, Wonderful, (323 reviews)
  • cleanliness
    Stay near Multiplaza Pacific Mall with relaxing outdoor pool and spa treatments.
The price is $206
$226 total
includes taxes & fees
Apr 3 - Apr 4
The Westin Panama
Sheraton Grand Panama
Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,003 reviews)
  • cleanliness
    Enjoy art deco elegance and spa pampering just minutes from Panama's prime shopping.
The price is $127
$139 total
includes taxes & fees
Apr 3 - Apr 4
Sheraton Grand Panama
Aloft Panama
Aloft Panama
3.5 star property
San Francisco
8.6 out of 10, Excellent, (983 reviews)
  • cleanliness
    Energize at this urban retreat with a nightclub and poolside drinks in Panama City.
The price is $112
$123 total
includes taxes & fees
Mar 21 - Mar 22
Aloft Panama
JW Marriott Panama
JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Set foot in Panama City's luxurious oasis near Multiplaza Pacific Mall and Avenida Balboa.
The price is $237
$261 total
includes taxes & fees
Apr 11 - Apr 12
JW Marriott Panama
Ramada Plaza by Wyndham Panama Punta Pacifica
Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,148 reviews)
  • cleanliness
    Enjoy easy access to top malls and attractions from this Panama City locale.
The price is $115
$126 total
includes taxes & fees
Mar 21 - Mar 22
Ramada Plaza by Wyndham Panama Punta Pacifica
Residence Inn by Marriott Panama City
Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.2 out of 10, Wonderful, (578 reviews)
  • cleanliness
    Relax in Panama City near the airport with complimentary transit and a rooftop.
The price is $178
$195 total
includes taxes & fees
Apr 5 - Apr 6
Residence Inn by Marriott Panama City
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,120 reviews)
  • cleanliness
    Waterfront oasis in Panama City with soothing spa and panoramic city views.
The price is $108
$119 total
includes taxes & fees
Mar 22 - Mar 23
Plaza Paitilla Inn Hotel
Courtyard by Marriott Panama Multiplaza Mall
Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Enjoy prime mall access and dining within steps of Panama's bustling city center.
The price is $105
$116 total
includes taxes & fees
Apr 11 - Apr 12
Courtyard by Marriott Panama Multiplaza Mall
Las Americas Golden Tower Panama
Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,021 reviews)
  • cleanliness
    Modern hotel with a full-service spa, near vibrant Avenida Balboa and Cinta Costera.
The price is $158
$174 total
includes taxes & fees
Apr 12 - Apr 13
Las Americas Golden Tower Panama
Decapolis Hotel Panama City
Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,592 reviews)
  • cleanliness
    Luxurious stay in Panama City with a casino, outdoor pool, and poolside bar.
The price is $133
$146 total
includes taxes & fees
Mar 15 - Mar 16
Decapolis Hotel Panama City
Megapolis Hotel Panamá
Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very Good, (1,451 reviews)
  • cleanliness
    Luxurious casino hotel on Avenida Balboa with rooftop terrace and poolside bar.
The price is $169
$186 total
includes taxes & fees
Apr 6 - Apr 7
Megapolis Hotel Panamá
Nomada Container Hotel Panama City
Nomada Container Hotel Panama City
3.0 star property
Bella Vista
8.8 out of 10, Excellent, (172 reviews)
  • cleanliness
    Discover unique container lodging in Panama City, minutes from Cinta Costera.
The price is $71
$78 total
includes taxes & fees
Mar 16 - Mar 17
Nomada Container Hotel Panama City
Hospedium Princess Hotel Panama
Hospedium Princess Hotel Panama
3.5 star property
Bella Vista
7.4 out of 10, Good, (784 reviews)
The price is $55
$60 total
includes taxes & fees
Apr 12 - Apr 13
Hospedium Princess Hotel Panama
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Luxurious casino resort offering airport shuttle and international dining, just minutes from Vía Argentina.
The price is $159
$175 total
includes taxes & fees
Mar 28 - Mar 29
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (5,076 reviews)
  • cleanliness
    Upscale Panama City hotel with 3 restaurants and outdoor pool near Avenida Balboa.
The price is $157
$172 total
includes taxes & fees
Mar 30 - Mar 31
Hotel Riu Plaza Panama
Panama House Bed & Breakfast
Panama House Bed & Breakfast
2.5 star property
Bella Vista
9.0 out of 10, Wonderful, (196 reviews)
The price is $34
$38 total
includes taxes & fees
Mar 16 - Mar 17
Panama House Bed & Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Santa Clara

Learn more about Santa Clara

The region around Santa Clara is home to attractions such as Culebra Cut and Albrook Shopping Mall.

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Frequently asked questions

Can I book a refundable accommodation in Santa Clara?
If you want the flexibility to change your plans to Santa Clara, most properties offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Santa Clara be like during my trip?
With an average temperature of 78°F, Santa Clara is a great place if you want to enjoy the sunshine year all year long.
Why should I book my Santa Clara accommodation with Hotels.com?
There are plenty of reasons to book your Santa Clara travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.