
Hotels in Pamplico
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in Pamplico?




Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2523)
8.6/10
Excellent
(2523)
The price is $70
$70
$79 total
includes taxes & fees
Jan 4 - Jan 5




Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2227)
9.0/10
Wonderful
(2227)
The price is $85
$85
$95 total
includes taxes & fees
Jan 4 - Jan 5




Comfort Inn & Suites Florence Center Area
Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.2 out of 10, Wonderful, (1191)
9.2/10
Wonderful
(1191)
The price is $98
$98
$110 total
includes taxes & fees
Jan 18 - Jan 19




Hyatt Place Florence Downtown
Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1004)
9.0/10
Wonderful
(1004)
The price is $100
$100
$112 total
includes taxes & fees
Jan 12 - Jan 13




Best Western Inn
Best Western Inn
2.5 star property
Florence
7.6 out of 10, Good, (1005)
7.6/10
Good
(1005)
The price is $89
$89
$100 total
includes taxes & fees
Jan 4 - Jan 5




Spark by Hilton Florence North I-95, SC
Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.0 out of 10, Very Good, (33)
8.0/10
Very Good
(33)
The price is $97
$97
$112 total
includes taxes & fees
Jan 8 - Jan 9




Microtel Inn & Suites by Wyndham Florence
Microtel Inn & Suites by Wyndham Florence
2.0 star property
Florence
6.8 out of 10, (1000)
6.8/10
(1000)
The price is $61
$61
$68 total
includes taxes & fees
Jan 11 - Jan 12




Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1010)
8.6/10
Excellent
(1010)
The price is $114
$114
$128 total
includes taxes & fees
Jan 18 - Jan 19




Hampton Inn & Suites Florence Center
Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (830)
9.0/10
Wonderful
(830)
The price is $98
$98
$109 total
includes taxes & fees
Jan 25 - Jan 26




La Quinta Inn & Suites by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
8.0 out of 10, Very Good, (1683)
8.0/10
Very Good
(1683)
The price is $94
$94
$105 total
includes taxes & fees
Jan 12 - Jan 13




Days Inn by Wyndham Florence/I-95 North
Days Inn by Wyndham Florence/I-95 North
2.0 star property
Florence
6.8 out of 10, (1001)
6.8/10
(1001)
The price is $59
$59
$66 total
includes taxes & fees
Jan 12 - Jan 13




Fairfield Inn & Suites by Marriott Florence I-20
Fairfield Inn & Suites by Marriott Florence I-20
2.5 star property
Florence
9.0 out of 10, Wonderful, (569)
9.0/10
Wonderful
(569)
The price is $110
$110
$123 total
includes taxes & fees
Jan 12 - Jan 13




Super 8 by Wyndham Florence
Super 8 by Wyndham Florence
2.0 star property
Florence
7.0 out of 10, Good, (1002)
7.0/10
Good
(1002)
The price is $58
$58
$65 total
includes taxes & fees
Jan 8 - Jan 9




Quality Inn & Suites Florence Civic Center
Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
7.8 out of 10, Good, (1255)
7.8/10
Good
(1255)
The price is $79
$79
$88 total
includes taxes & fees
Feb 2 - Feb 3




Comfort Suites Florence I-95
Comfort Suites Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1002)
8.4/10
Very Good
(1002)
The price is $103
$103
$119 total
includes taxes & fees
Jan 4 - Jan 5




Tru by Hilton Florence I-95
Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1003)
8.4/10
Very Good
(1003)
The price is $93
$93
$108 total
includes taxes & fees
Jan 8 - Jan 9




Residence Inn Marriott Florence
Residence Inn Marriott Florence
3.0 star property
Florence
8.8 out of 10, Excellent, (490)
8.8/10
Excellent
(490)
The price is $99
$99
$111 total
includes taxes & fees
Jan 6 - Jan 7




Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.2 out of 10, Wonderful, (1003)
9.2/10
Wonderful
(1003)
The price is $110
$110
$123 total
includes taxes & fees
Jan 11 - Jan 12




The Inn at the Crossroads
The Inn at the Crossroads
2.0 star property
Lake City
9.4 out of 10, Exceptional, (837)
9.4/10
Exceptional
(837)
The price is $143
$143
$160 total
includes taxes & fees
Jan 16 - Jan 17




Hampton Inn & Suites Florence-North-I-95
Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (830)
9.0/10
Wonderful
(830)
The price is $114
$114
$127 total
includes taxes & fees
Jan 9 - Jan 10
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Budget hotels in Pamplico and vicinity




7.0 out of 10, Good, (1002)
7.0/10
Good
(1002)
The price is $58
$58
$65 total
includes taxes & fees
Jan 8 - Jan 9




7.0 out of 10, Good, (322)
7.0/10
Good
(322)
The price is $55
$55
$61 total
includes taxes & fees
Jan 15 - Jan 16




8.6 out of 10, Excellent, (2523)
8.6/10
Excellent
(2523)
The price is $70
$70
$79 total
includes taxes & fees
Jan 4 - Jan 5




7.4 out of 10, Good, (686)
7.4/10
Good
(686)
The price is $68
$68
$76 total
includes taxes & fees
Feb 2 - Feb 3




9.2 out of 10, Wonderful, (122)
9.2/10
Wonderful
(122)
The price is $77
$77
$86 total
includes taxes & fees
Jan 6 - Jan 7




8.2 out of 10, Very Good, (942)
8.2/10
Very Good
(942)
The price is $98
$98
$107 total
includes taxes & fees
Jan 8 - Jan 9




Quality Inn & Suites Florence Civic Center
Quality Inn & Suites Florence Civic Center2.5 star property
Florence
7.8 out of 10, Good, (1255)
7.8/10
Good
(1255)
The price is $79
$79
$88 total
includes taxes & fees
Feb 2 - Feb 3




9.0 out of 10, Wonderful, (2227)
9.0/10
Wonderful
(2227)
The price is $85
$85
$95 total
includes taxes & fees
Jan 4 - Jan 5




7.6 out of 10, Good, (1005)
7.6/10
Good
(1005)
The price is $89
$89
$100 total
includes taxes & fees
Jan 4 - Jan 5




8.4 out of 10, Very Good, (1003)
8.4/10
Very Good
(1003)
The price is $93
$93
$108 total
includes taxes & fees
Jan 8 - Jan 9




La Quinta Inn & Suites by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florence3.0 star property
Florence
8.0 out of 10, Very Good, (1683)
8.0/10
Very Good
(1683)
The price is $94
$94
$105 total
includes taxes & fees
Jan 12 - Jan 13




7.8 out of 10, Good, (703)
7.8/10
Good
(703)
The price is $97
$97
$109 total
includes taxes & fees
Jan 18 - Jan 19




9.0 out of 10, Wonderful, (830)
9.0/10
Wonderful
(830)
The price is $98
$98
$109 total
includes taxes & fees
Jan 25 - Jan 26




8.4 out of 10, Very Good, (660)
8.4/10
Very Good
(660)
The price is $98
$98
$113 total
includes taxes & fees
Jan 11 - Jan 12




Spark by Hilton Florence North I-95, SC
Spark by Hilton Florence North I-95, SC2.5 star property
Florence
8.0 out of 10, Very Good, (33)
8.0/10
Very Good
(33)
The price is $97
$97
$112 total
includes taxes & fees
Jan 8 - Jan 9




Comfort Inn & Suites Florence Center Area
Comfort Inn & Suites Florence Center Area2.5 star property
Florence
9.2 out of 10, Wonderful, (1191)
9.2/10
Wonderful
(1191)
The price is $98
$98
$110 total
includes taxes & fees
Jan 18 - Jan 19




8.8 out of 10, Excellent, (490)
8.8/10
Excellent
(490)
The price is $99
$99
$111 total
includes taxes & fees
Jan 6 - Jan 7




8.6 out of 10, Excellent, (259)
8.6/10
Excellent
(259)
The price is $99
$99
$111 total
includes taxes & fees
Jan 11 - Jan 12




7.8 out of 10, Good, (378)
7.8/10
Good
(378)
The price is $99
$99
$108 total
includes taxes & fees
Jan 8 - Jan 9




9.0 out of 10, Wonderful, (1004)
9.0/10
Wonderful
(1004)
The price is $100
$100
$112 total
includes taxes & fees
Jan 12 - Jan 13
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Pamplico
Family friendly
Pet friendly
Check out reviews of Pamplico hotels guests love

Hampton Inn & Suites Florence Center
10/10 Excellent
"Staff is AMAZING there! From check in to housekeeping and the best complimentary breakfast we have had ANYWHERE. DEFINITELY our new place to stay halfway to Florida for the winter!!! Keep up the good work!"

Comfort Inn & Suites Florence Center Area
10/10 Excellent
"Fast check in, comfortable bed, quiet setting and a wonderful breakfast."

Hyatt Place Florence Downtown
10/10 Excellent
"N/A"

Days Inn by Wyndham Florence/I-95 North
10/10 Excellent
"It was clean. I only needed to sleep to be able to drive the rest of the way home. Mission accomplished!"

Quality Inn & Suites Florence Civic Center
10/10 Excellent
"Newly renovated. Very nice. King bed was "

Howard Johnson by Wyndham Florence
10/10 Excellent
"Clean rooms, good breakfast "

Days Inn by Wyndham Florence Near Civic Center
10/10 Excellent
"Receptionist was very professional and polite. And took her time to answer every question. "

Aloft Florence
10/10 Excellent
"Everything was great!"

Residence Inn Marriott Florence
10/10 Excellent
"Nothing in particular. It was just a good stay."
Frequently asked questions
Can I book refundable accommodations in Pamplico?
If you want the flexibility to change your plans to Pamplico, most hotels provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Pamplico be like during my vacation?
July and August are typically the warmest months in Pamplico when the average temp is 78°F. January and February are the coldest months when the average temperature is 50°F. August and July are the months with the most rain.
Why should I book my Pamplico hotel through Hotels.com?
There are lots of reasons to book your Pamplico trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.